Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: Evidence for a hydroxyl-radical-like mechanism

Free Radical Biology and Medicine

Volumn 42, Issue 8, 2007, Pages 1278-1289

  Kennett, Eleanor C ^a   Davies, Michael J ^a,b  

^a HEART RESEARCH INSTITUTE   (Australia)

^b University of Sydney   (Australia)

Author keywords

EPR; Extracellular matrix; Free radicals; Glycosaminoglycans; Hyaluronan; Hydroxyl radical; Peroxynitrite

Indexed keywords

CHONDROITIN; DERMATAN; DISACCHARIDE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HEPARIN; HYALURONIC ACID; HYDROXYL RADICAL; MONOSACCHARIDE; PEROXYNITRITE; PEROXYNITROUS ACID;

ARTICLE; CELL DAMAGE; EXTRACELLULAR MATRIX; FRAGMENTATION REACTION; GENERATOR; INFLAMMATION; OXIDATION; PH; PRIORITY JOURNAL; PROTEIN DEGRADATION; SPIN TRAPPING;

CHONDROITIN; ELECTRON SPIN RESONANCE SPECTROSCOPY; EXTRACELLULAR MATRIX; GLYCOSAMINOGLYCANS; HEPARIN; HYALURONIC ACID; HYDROXYL RADICAL; KINETICS; PEROXYNITROUS ACID; SOLUTIONS;

EID: 33947246924     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2007.01.030     Document Type: Article

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