Increased levels of soluble CD226 in sera accompanied by decreased membrane CD226 expression on peripheral blood mononuclear cells from cancer patients

BMC Immunology

Volumn 10, Issue , 2009, Pages

  Xu, Zhuwei ^a   Zhang, Tao ^b   Zhuang, Ran ^a   Zhang, Yun ^a   Jia, Wei ^a   Song, Chaojun ^a   Yang, Kun ^a   Yang, Angang ^a   Jin, Boquan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD226 ANTIGEN; FC RECEPTOR; PROTEINASE; T LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG; HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; BLOOD SAMPLING; CANCER IMMUNOTHERAPY; CANCER PATIENT; CELL CULTURE; CELL ISOLATION; CELL MEMBRANE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; NATURAL KILLER CELL; PATIENT MONITORING; PERIPHERAL BLOOD MONONUCLEAR CELL; PREDICTION; SUPERNATANT; TUMOR CELL; TUMOR ESCAPE; CELL STRAIN K 562; CYTOTOXICITY; DRUG EFFECT; GENETIC ENGINEERING; GENETICS; IMMUNOLOGICAL PROCEDURES; IMMUNOLOGY; IMMUNOTHERAPY; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; NEOPLASM; PATHOLOGY;

ADULT; AGED; ANTIBODIES, MONOCLONAL; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CYTOTOXICITY, IMMUNOLOGIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC ENGINEERING; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOLOGIC TESTS; IMMUNOTHERAPY; K562 CELLS; LEUKOCYTES, MONONUCLEAR; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NEOPLASMS; RECOMBINANT FUSION PROTEINS; TUMOR ESCAPE;

EID: 67649868151     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-10-34     Document Type: Article

References (35)

1. Burns GF Triglia T Werkmeister JA Begley CG Boyd AW TLiSA1, a human T lineage-specific activation antigen involved in the differentiation of cytotoxic T lymphocytes and anomalous killer cells from their precursors J Exp Med 1985, 161:1063-78 2187589 2580933 10.1084/jem.161.5.1063
2. Scott JL Dunn SM Jin B Hillam AJ Walton S Berndt MC Murray AW Krissansen GW Burns GF Characterization of a novel membrane glycoprotein involved in platelet activation J Biol Chem 1989, 264:13475-82 2760031
3. Shibuya A Campbell D Hannum C Yssel H Franz-Bacon K McClanahan T Kitamura T Nicholl J Sutherland GR Lanier LL et al DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes Immunity 1996, 4:573-81 10.1016/S1074-7613(00)70060-4 8673704
4. Sherrington PD Scott JL Jin B Simmons D Dorahy DJ Lloyd J Brien JH Aebersold RH Adamson J Zuzel M et al TLiSA1 (PTA1) activation antigen implicated in T cell differentiation and platelet activation is a member of the immunoglobulin superfamily exhibiting distinctive regulation of expression J Biol Chem 1997, 272:21735-44 10.1074/jbc.272.35.21735 9268302
5. Tian F Li D Xia H Liu X Jia W Sun C Sun K Jin B Isolation of cDNAs encoding gibbon and monkey platelet and T cell activation antigen 1 (PTA1) DNA Seq 1999, 10:155-61 10.3109/10425179909033941 10647817
6. Bottino C Castriconi R Pende D Rivera P Nanni M Carnemolla B Cantoni C Grassi J Marcenaro S Reymond N et al Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule J Exp Med 2003, 198:557-67 2194180 12913096 10.1084/ jem.20030788
7. Tahara-Hanaoka S Shibuya K Onoda Y Zhang H Yamazaki S Miyamoto A Honda S Lanier LL Shibuya A Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112) Int Immunol 2004, 16:533-8 10.1093/intimm/dxh059 15039383
8. Pende D Spaggiari GM Marcenaro S Martini S Rivera P Capobianco A Falco M Lanino E Pierri I Zambello R et al Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: Evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112) Blood 2005, 105:2066-73 10.1182/blood-2004-09-3548 15536144
9. Castriconi R Dondero A Corrias MV Lanino E Pende D Moretta L Bottino C Moretta A Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: Critical role of DNAX accessory molecule-1-poliovirus receptor interaction Cancer Res 2004, 64:9180-4 10.1158/0008-5472.CAN-04-2682 15604290
10. Pende D Bottino C Castriconi R Cantoni C Marcenaro S Rivera P Spaggiari GM Dondero A Carnemolla B Reymond N e al PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis Mol Immunol 2005, 42:463-9 10.1016/ j.molimm.2004.07.028 15607800
11. El-Sherbiny YM Meade JL Holmes TD McGonagle D Mackie SL Morgan AW Cook G Feyler S Richards SJ Davies FE et al The requirement for DNAM-1, NKG2D, and NKp46 in the natural killer cell-mediated killing of myeloma cells Cancer Res 2007, 67:8444-9 10.1158/0008-5472.CAN-06-4230 17875681
12. Bottino C Castriconi R Moretta L Moretta A Cellular ligands of activating NK receptors Trends Immunol 2005, 26:221-6 10.1016/ j.it.2005.02.007 15797513
13. Bryceson YT March ME Ljunggren HG Long EO Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion Blood 2006, 107:159-66 1895346 16150947 10.1182/ blood-2005-04-1351
14. Fuchs A Colonna M The role of NK cell recognition of nectin and nectin-like proteins in tumor immunosurveillance Semin Cancer Biol 2006, 16:359-66 10.1016/j.semcancer.2006.07.002 16904340
15. Sloan KE Eustace BK Stewart JK Zehetmeier C Torella C Simeone M Roy JE Unger C Louis DN Ilag LL et al CD155/PVR plays a key role in cell motility during tumor cell invasion and migration BMC Cancer 2004, 4:73 524493 15471548 10.1186/1471-2407-4-73
16. Morimoto K Satoh-Yamaguchi K Hamaguchi A Inoue Y Takeuchi M Okada M Ikeda W Takai Y Imai T Interaction of cancer cells with platelets mediated by Necl-5/poliovirus receptor enhances cancer cell metastasis to the lungs Oncogene 2008, 27:264-73 10.1038/sj.onc.1210645 17637752
17. Baury B Masson D McDermott BM Jr Jarry A Blottiere HM Blanchardie P Laboisse CL Lustenberger P Racaniello VR Denis MG Identification of secreted CD155 isoforms Biochem Biophys Res Commun 2003, 309:175-82 10.1016/S0006-291X(03)01560-2 12943679
18. Jia W Liu XS Zhu Y Li Q Han WN Zhang Y Zhang JS Yang K Zhang XH Jin BQ Preparation and characterization of mabs against different epitopes of CD226 (PTA1) Hybridoma 2000, 19:489-94 10.1089/027245700750053986 11152401
19. Masson D Jarry A Baury B Blanchardie P Laboisse C Lustenberger P Denis MG Overexpression of the CD155 gene in human colorectal carcinoma Gut 2001, 49:236-40 1728395 11454801 10.1136/gut.49.2.236
20. Ravens I Seth S Forster R Bernhardt G Characterization and identification of Tage4 as the murine orthologue of human poliovirus receptor/CD155 Biochem Biophys Res Commun 2003, 312:1364-71 10.1016/ j.bbrc.2003.11.067 14652024
21. Ochiai H Moore SA Archer GE Okamura T Chewning TA Marks JR Sampson JH Gromeier M Treatment of intracerebral neoplasia and neoplastic meningitis with regional delivery of oncolytic recombinant poliovirus Clin Cancer Res 2004, 10:4831-8 10.1158/1078-0432.CCR-03-0694 15269159
22. Bai F Guo X Yang L Wang J Shi Y Zhang F Zhai H Lu Y Xie H Wu K et al Establishment and characterization of a high metastatic potential in the peritoneum for human gastric cancer by orthotopic tumor cell implantation Dig Dis Sci 2007, 52:1571-8 10.1007/s10620-006-9570-x 17404872
23. Stolpe van de A Saag van der PT Intercellular adhesion molecule-1 J Mol Med 1996, 74:13-33 10.1007/BF00202069 8834767
24. Knox PG Milner AE Green NK Eliopoulos AG Young LS Inhibition of metalloproteinase cleavage enhances the cytotoxicity of Fas ligand J Immunol 2003, 170:677-85 12517928
25. Albitar M Do KA Johnson MM Giles FJ Jilani I O'Brien S Cortes J Thomas D Rassenti LZ Kipps TJ et al Free circulating soluble CD52 as a tumor marker in chronic lymphocytic leukemia and its implication in therapy with anti-CD52 antibodies Cancer 2004, 101:999-1008 10.1002/cncr.20477 15329909
26. Hakulinen J Junnikkala S Sorsa T Meri S Complement inhibitor membrane cofactor protein (MCP; CD46) is constitutively shed from cancer cell membranes in vesicles and converted by a metalloproteinase to a functionally active soluble form Eur J Immunol 2004, 34:2620-9 10.1002/ eji.200424969 15307194
27. Hallermalm K De Geer A Kiessling R Levitsky V Levitskaya J Autocrine secretion of Fas ligand shields tumor cells from Fas-mediated killing by cytotoxic lymphocytes Cancer Res 2004, 64:6775-82 10.1158/ 0008-5472.CAN-04-0508 15374996
28. Waldhauer I Steinle A Proteolytic release of soluble UL16-binding protein 2 from tumor cells Cancer Res 2006, 66:2520-6 10.1158/ 0008-5472.CAN-05-2520 16510567
29. Marten A von Lilienfeld-Toal M Buchler MW Schmidt J Soluble MIC is elevated in the serum of patients with pancreatic carcinoma diminishing gammadelta T cell cytotoxicity Int J Cancer 2006, 119:2359-65 10.1002/ ijc.22186 16929491
30. Cao W Xi X Hao Z Li W Kong Y Cui L Ma C Ba D He W RAET1E2, a soluble isoform of the UL16-binding protein RAET1E produced by tumor cells, inhibits NKG2D-mediated NK cytotoxicity J Biol Chem 2007, 282:18922-8 10.1074/jbc.M702504200 17470428
31. Harrison D Phillips JH Lanier LL Involvement of a metalloprotease in spontaneous and phorbol ester-induced release of natural killer cell-associated Fc gamma RIII (CD16-II) J Immunol 1991, 147:3459-65 1834741
32. Gutwein P Oleszewski M Mechtersheimer S Agmon-Levin N Krauss K Altevogt P Role of Src kinases in the ADAM-mediated release of L1 adhesion molecule from human tumor cells J Biol Chem 2000, 275:15490-7 10.1074/ jbc.275.20.15490 10809781
33. Tsakadze NL Sithu SD Sen U English WR Murphy G D'Souza SE Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) mediates the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1) J Biol Chem 2006, 281:3157-64 10.1074/jbc.M510797200 16332693
34. Moldovan I Galon J Maridonneau-Parini I Roman Roman S Mathiot C Fridman WH Sautes-Fridman C Regulation of production of soluble Fc gamma receptors type III in normal and pathological conditions Immunol Lett 1999, 68:125-34 10.1016/S0165-2478(99)00041-3 10397167
35. DeClerck YA Imren S Montgomery AM Mueller BM Reisfeld RA Laug WE Proteases and protease inhibitors in tumor progression Adv Exp Med Biol 1997, 425:89-97 9433492