Hepatocyte transplantation improves phenotype and extends survival in a murine model of intermediate maple syrup urine disease

Molecular Therapy

Volumn 17, Issue 7, 2009, Pages 1266-1273

  Skvorak, Kristen J ^a   Paul, Harbhajan S ^b   Dorko, Kenneth ^c   Marongiu, Fabio ^c   Ellis, Ewa ^c   Chace, Donald ^d   Ferguson, Carolyn ^c   Gibson, K Michael ^a,c   Homanics, Gregg E ^c   Strom, Stephen C ^c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b Biomcd Research and Technologies Inc   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d Departent of Pediatrix Analytical   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOISOVALERATE DEHYDROGENASE (LIPOAMIDE); ALANINE; BRANCHED CHAIN AMINO ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL THERAPY; CONTROLLED STUDY; ENGRAFTMENT; ENZYME ACTIVITY; GENE SEQUENCE; GENE TARGETING; HEPATOCYTE TRANSPLANTATION; LIVER CELL; LIVER TRANSPLANTATION; MAPLE SYRUP URINE DISEASE; METABOLIC REGULATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; WEANING;

3-METHYL-2-OXOBUTANOATE DEHYDROGENASE (LIPOAMIDE); ANIMALS; BODY WEIGHT; DISEASE MODELS, ANIMAL; HEPATOCYTES; LIVER; MAPLE SYRUP URINE DISEASE; MICE; PHENOTYPE; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SURVIVAL ANALYSIS; TISSUE THERAPY;

ACER; MURINAE; MUS;

EID: 67649861071     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2009.99     Document Type: Article

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