Topoisomerase II α Status in Renal Medullary Carcinoma: Immuno-Expression and Gene Copy Alterations of a Potential Target of Therapy

Journal of Urology

Volumn 182, Issue 2, 2009, Pages 735-740

  Albadine, Roula ^a   Wang, Wenle ^a   Brownlee, Noel A ^a   Toubaji, Antoun ^a   Billis, Athanase ^d   Argani, Perdram ^a   Epstein, Jonathan I ^b   Garvin, A Julian ^c   Cousi, Rima ^b   Schaeffer, Edward M ^a   Pavlovich, Christian ^a   Netto, George J ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

carcinoma; DNA topoisomerase II alpha; gene deletion; kidney; kidney medulla

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; ETOPOSIDE; GEMCITABINE; KI 67 ANTIGEN; METHOTREXATE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY KI 67; PACLITAXEL; TOPOISOMERASE II ALPHA; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE;

ADOLESCENT; ADULT; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CANCER SURVIVAL; CANCER TISSUE; CELL NUCLEUS; CELL PROLIFERATION; CENTROMERE; CHILD; CHROMOSOME 17; CONTROLLED STUDY; ENZYME SPECIFICITY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE DELETION; GENE EXPRESSION PROFILING; GENE FREQUENCY; GENE LOCUS; GENE NUMBER; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY CARCINOMA; KIDNEY MEDULLA; MALE; MEDULLARY CARCINOMA; MOLECULAR PROBE; MONOSOMY; PRIORITY JOURNAL; PROTEIN PROCESSING; SCHOOL CHILD; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

ADOLESCENT; ADULT; ANTIGENS, NEOPLASM; CARCINOMA, MEDULLARY; CHILD; DNA TOPOISOMERASES, TYPE II, EUKARYOTIC; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KIDNEY NEOPLASMS; YOUNG ADULT;

EID: 67649819325     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2009.03.078     Document Type: Article

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