Local delivery of synthetic prostacycline agonist augments collateral growth and improves cardiac function in a swine chronic cardiac ischemia model

Life Sciences

Volumn 85, Issue 5-6, 2009, Pages 255-261

  Iwata, Hiroshi ^a   Nakamura, Kazuto ^a,b   Sumi, Makoto ^a,c   Ninomiya, Mikio ^a   Sakai, Yoshiki ^d   Hirata, Yoichiro ^a,e   Akaike, Masahi ^e   Igarashi, Takashi ^a   Takamoto, Shinichi ^a   Nagai, Ryozo ^a   Sata, Masataka ^a,e  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF YAMANASHI   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d ONO PHARMACEUTICAL CO   (Japan)

^e UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Ischemic heart disease; Prostacyclin; Therapeutic angiogenesis

Indexed keywords

7,8 DIHYDRO 5 [2 [[ALPHA (3 PYRIDYL)BENZYLIDENE]AMINOOXY]ETHYL] 1 NAPHTHYLOXYACETIC ACID; POLYGLACTIN; SCATTER FACTOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAPILLARY DENSITY; COLLATERAL CIRCULATION; CONTROLLED STUDY; DRUG EFFICACY; ENDOTHELIUM CELL; FIBROBLAST; HEART INDEX; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE FIBROSIS; HEART MUSCLE ISCHEMIA; HEART OUTPUT; HEART VENTRICLE REMODELING; HEART VENTRICLE WALL MOTION; HUMAN; HUMAN CELL; LIMB ISCHEMIA; MALE; NONHUMAN; RAT; SINGLE DRUG DOSE; SLOW RELEASE FORMULATION; SWINE;

ANIMALS; CELLS, CULTURED; COLLATERAL CIRCULATION; DELAYED-ACTION PREPARATIONS; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; FIBROBLASTS; HEPATOCYTE GROWTH FACTOR; HINDLIMB; LASER-DOPPLER FLOWMETRY; MALE; MICROCIRCULATION; MYOCARDIAL ISCHEMIA; NEOVASCULARIZATION, PATHOLOGIC; PROSTAGLANDINS I; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; SWINE;

RATTUS; SUIDAE;

EID: 67649814627     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2009.06.002     Document Type: Article

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