Role of stem and progenitor cells in postmyocardial infarction patients

Minerva Cardioangiologica

Volumn 57, Issue 2, 2009, Pages 219-231

  Liu, X ^a   Dauwe, D ^a   Patel, A ^a   Janssens, S ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Myocardial infarction; Myocytes, cardiac; Stem cells

Indexed keywords

ACUTE HEART INFARCTION; ADULT STEM CELL; CLINICAL TRIAL; EMBRYONIC STEM CELL; FOLLOW UP; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; NONHUMAN; PLURIPOTENT STEM CELL; REVIEW;

EID: 67649661961     PISSN: 00264725     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (62)

1. Sutton MG, Sharpe N. Left ventricular remodeling after myocardial infarction: pathophysiology and therapy. Circulation 2000;101:2981-2988 (Pubitemid 30415891)
2. Stone GW, Grines CL, Cox DA, Garcia E, Tcheng JE, Griffin JJ et al. Comparison of angioplasty with stenting, with or without abciximab, in acute myocardial infarction. N Engl J Med 2002;346:957-966 (Pubitemid 34983245)
3. Pfeffer MA, McMurray JJ, Velazquez EJ, Rouleau JL, Kober L, Maggioni AP et al. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 2003;349:1893-1906 (Pubitemid 37409706)
4. Ezekowitz JA, Kaul P, Bakal JA, Armstrong PW, Welsh RC, McAlister FA. Declining in-hospital mortality and increasing heart failure incidence in elderly patients with first myocardial infarction. J Am Coll Cardiol 2009;53:13-20.
5. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001;410:701-705 (Pubitemid 32290358)
6. Matsuura K, Nagai T, Nishigaki N, Oyama T, Nishi J, Wada H et al. Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes. J Biol Chem 2004;279:11384-11391 (Pubitemid 38401637)
7. Fazel S, Cimini M, Chen L, Li S, Angoulvant D, Fedak P et al. Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. J Clin Invest 2006;116:1865-1877 (Pubitemid 44033311)
8. Deb A, Wang S, Skelding KA, Miller D, Simper D, Caplice NM. Bone marrow-derived cardiomyocytes are present in adult human heart: A study of gender-mismatched bone marrow transplantation patients. Circulation 2003;107:1247-1249 (Pubitemid 36314405)
9. Doss MX, Koehler CI, Gissel C, Hescheler J, Sachinidis A. Embryonic stem cells: a promising tool for cell replacement therapy. J Cell Mol Med 2004;8:465-473 (Pubitemid 44145479)
10. Hodgson DM, Behfar A, Zingman LV, Kane GC, Perez-Terzic C, Alekseev AE et al. Stable benefit of embryonic stem cell therapy in myocardial infarction. Am J Physiol Heart Circ Physiol 2004;287:H471-9. (Pubitemid 38955274)
11. Fujikawa T, Oh SH, Pi L, Hatch HM, Shupe T, Petersen BE. Teratoma formation leads to failure of treatment for type I diabetes using embryonic stem cell-derived insulin-producing cells. Am J Pathol 2005;166:1781-1791 (Pubitemid 40734401)
12. Swijnenburg RJ, Tanaka M, Vogel H, Baker J, Kofidis T, Gunawan F et al. Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium. Circulation 2005;112(9 Suppl):I166-172. (Pubitemid 41266669)
13. Caspi O, Huber I, Kehat I, Habib M, Arbel G, Gepstein A et al. Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts. J Am Coll Cardiol 2007;50:1884-1893 (Pubitemid 350007960)
14. Kumar D, Kamp TJ, LeWinter MM. Embryonic stem cells: differentiation into cardiomyocytes and potential for heart repair and regeneration. Coron Artery Dis 2005;16:111-116 (Pubitemid 40393186)
15. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-676 (Pubitemid 44233629)
16. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-872 (Pubitemid 350138099)
17. Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007;318:1917-1920
18. Passier R, van Laake LW, Mummery CL. Stem-cell-based therapy and lessons from the heart. Nature 2008;453:322-329 (Pubitemid 351693138)
19. Janssens S. Human embryonic stem cells for cardiac repair: the focus is on refined selection and cardiopoietic programming. Heart 2007;93:1173-1174 (Pubitemid 47492895)
20. Wollert KC. Cell therapy for acute myocardial infarction. Curr Opin Pharmacol 2008;8:202-210
21. Reffelmann T, Kloner RA. Cellular cardiomyoplasty - cardiomyocytes, skeletal myoblasts, or stem cells for regenerating myocardium and treatment of heart failure? Cardiovasc Res 2003;58:358-368 (Pubitemid 36570394)
22. Fransioli J, Bailey B, Gude NA, Cottage CT, Muraski JA, Emmanuel G et al. Evolution of the c-kit-positive cell response to pathological challenge in the myocardium. Stem Cells 2008;26:1315-1324
23. Messina E, De Angelis L, Frati G, Morrone S, Chimenti S, Fiordaliso F et al. Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res 2004;95:911-921 (Pubitemid 39435006)
24. Torella D, Ellison GM, Karakikes I, Nadal-Ginard B. Growth-factor- mediated cardiac stem cell activation in myocardial regeneration. Nat Clin Pract Cardiovasc Med 2007;4(Suppl 1):S46-51. (Pubitemid 46164270)
25. Sipido KR, Janssens SP. How old is your heart? Circ Res 2007;101:323-325
26. Haider H, Ashraf M. Bone marrow stem cell transplantation for cardiac repair. Am J Physiol Heart Circ Physiol 2005;288:H2557-67.
27. Balsam LB, Wagers AJ, Christensen JL, Kofidis T, Weissman IL, Robbins RC. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature 2004;428:668-673 (Pubitemid 38524811)
28. Murry CE, Soonpaa MH, Reinecke H, Nakajima H, Nakajima HO, Rubart M et al. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature 2004;428:664-668 (Pubitemid 38524810)
29. Silva GV, Litovsky S, Assad JA, Sousa AL, Martin BJ, Vela D et al. Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model. Circulation 2005;111:150-156 (Pubitemid 40139725)
30. Murry CE, Reinecke H, Pabon LM. Regeneration gaps: observations on stem cells and cardiac repair. J Am Coll Cardiol 2006;47:1777-1785
31. Goodell MA, Jackson KA, Majka SM, Mi T, Wang H, Pocius J et al. Stem cell plasticity in muscle and bone marrow. Ann N Y Acad Sci 2001;938:208-18; discussion 218-220 (Pubitemid 32620034)
32. Laflamme MA, Murry CE. Regenerating the heart. Nat Biotechnol 2005;23:845-856 (Pubitemid 43093128)
33. Chen SL, Fang WW, Ye F, Liu YH, Qian J, Shan SJ et al. Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction. Am J Cardiol 2004;94:92-95 (Pubitemid 38813459)
34. Assmus B, Schachinger V, Teupe C, Britten M, Lehmann R, Dobert N et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation 2002;106:3009-3017 (Pubitemid 35440281)
35. Schachinger V, Assmus B, Britten MB, Honold J, Lehmann R, Teupe C et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: final one-year results of the TOPCARE-AMI Trial. J Am Coll Cardiol 2004;44:1690-1699 (Pubitemid 39369805)
36. Wollert KC, Meyer GP, Lotz J, Ringes-Lichtenberg S, Lippolt P, Breidenbach C et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet. 2004;364:141-148 (Pubitemid 38891685)
37. Janssens S, Dubois C, Bogaert J, Theunissen K, Deroose C, Desmet W et al. Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial. Lancet 2006;367:113-121 (Pubitemid 43077127)
38. Lunde K, Solheim S, Aakhus S, Arnesen H, Abdelnoor M, Egeland T et al. Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. N Engl J Med 2006;355:1199-1209 (Pubitemid 44427444)
39. Schachinger V, Erbs S, Elsasser A, Haberbosch W, Hambrecht R, Holschermann H et al. Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med 2006;355:1210-1221 (Pubitemid 44427445)
40. Meyer GP, Wollert KC, Lotz J, Steffens J, Lippolt P, Fichtner S et al. Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial. Circulation 2006;113:1287-1294 (Pubitemid 43739450)
41. Herbots L, D'Hooge J, Eroglu E, Thijs D, Ganame J, Claus P et al. Improved regional function after autologous tone marrow-derived stem cell transfer in patients with acute myocardial infarction: a randomized, double-blind strain rate imaging study. Eur Heart J 2008 2008 [Epub ahead of print].
42. Janssens S, Bogaert J, Dubois C, Van Cleemput J, Theunissen K, Kalantzis M et al. Long-term safety and efficacy of autologous bone marrow-derived stem cell transfer after acute myocardial infarction. Circulation 2006;114:II-515.
43. Penn MS. Stem-cell therapy after acute myocardial infarction: the focus should be on those at risk. Lancet 2006;367:87-88 (Pubitemid 43077108)
44. Rosenzweig A. Cardiac cell therapy mixed results from mixed cells. N Engl J Med 2006;355:1274-1277 (Pubitemid 44427452)
45. Seeger FH, Tonn T, Krzossok N, Zeiher AM, Dimmeler S. Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction. Eur Heart J 2007;28:766-772 (Pubitemid 46439231)
46. Assmus B, Fischer-Rasokat U, Honold J, Seeger FH, Fichtlscherer S, Tonn T et al. Transcoronary transplantation of functionally competent BMCs is associated with a decrease in natriuretic peptide serum levels and improved survival of patients with chronic postinfarction heart failure: results of the TOPCARE-CHD Registry. Circ Res 2007;100:1234-1241 (Pubitemid 46684137)
47. Schaefer A, Meyer GP, Fuchs M, Klein G, Kaplan M, Wollert KC et al. Impact of intracoronary bone marrow cell transfer on diastolic function in patients after acute myocardial infarction: results from the BOOST trial. Eur Heart J 2006;27:929-935
48. Dill T SV, Rolf A, Möllmann S, Thiele H, Tillmanns H, Assmus B et al. Intracoronary administration of bone marrow-derived progenitor cells improves left ventricular function in patients at risk for adverse remodeling after acute ST-segment elevation myocardial infarction: Results of the Reinfusion of Enriched Progenitor cells And Infarct Remodeling in Acute Myocardial Infarction study (REPAIR-AMI) cardiac Magnetic Resonance Imaging substudy. Am Heart J 2009 [Epub ahead of printing].
49. Abdel-Latif A, Bolli R, Tleyjeh IM, Montori VM, Perin EC, Hornung CA et al. Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis. Arch Intern Med 2007;167:989-997 (Pubitemid 46835786)
50. Martin-Rendon E, Brunskill SJ, Hyde CJ, Stanworth SJ, Mathur A, Watt SM. Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review. Eur Heart J 2008;29:1807-1818
51. Lipinski MJ, Biondi-Zoccai GG, Abbate A, Khianey R, Sheiban I, Bartunek J et al. Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of controlled clinical trials. J Am Coll Cardiol 2007;50:1761-1767 (Pubitemid 47600592)
52. Bartunek J, Dimmeler S, Drexler H, Fernandez-Aviles F, Galinanes M, Janssens S et al. The consensus of the task force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart. Eur Heart J 2006;27:1338-1340 (Pubitemid 43998109)
53. Huikuri HV, Kervinen K, Niemela M, Ylitalo K, Saily M, Koistinen P et al. Effects of intracoronary injection of mononuclear bone marrow cells on left ventricular function, arrhythmia risk profile, and restenosis after thrombolytic therapy of acute myocardial infarction. Eur Heart J 2008;29:2723-2732
54. Piek JJ. Intracoronary infusion of mononuclear cells after primary percutaneous coronary intervention: The HEBE trial. Circulation AHA Scientific Sessions 2008.
55. Tendera M, Wojakowski W, Ruzyllo W, Chojnowska L, Kepka C, Tracz W et al. Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre Myocardial Regeneration by Intracoronary Infusion of Selected Population of Stem Cells in Acute Myocardial Infarction (REGENT) Trial. Eur Heart J 2009 [Epub ahead of printing].
56. Gyongyosi M, Lang I, Dettke M, Beran G, Graf S, Sochor H et al. Combined delivery approach of bone marrow mononuclear stem cells early and late after myocardial infarction: the MYSTAR prospective, randomized study. Nat Clin Pract Cardiovasc Med 2009;6:70-81.
57. Hirsch A, Nijveldt R, van der Vleuten PA, Tio RA, van der Giessen WJ, Marques KM et al. Intracoronary infusion of autologous mononuclear bone marrow cells in patients with acute myocardial infarction treated with primary PCI: Pilot study of the multicenter HEBE trial. Catheter Cardiovasc Interv 2008;71:273-281
58. van der Laan A, Hirsch A, Nijveldt R, van der Vleuten PA, van der Giessen WJ, Doevendans PA et al. Bone marrow cell therapy after acute myocardial infarction: the HEBE trial in perspective, first results. Neth Heart J 2008;16:436-439
59. Erbs S, Linke A, Schachinger V, Assmus B, Thiele H, Diederich KW et al. Restoration of microvascular function in the infarct-related artery by intracoronary transplantation of bone marrow progenitor cells in patients with acute myocardial infarction: the Doppler Substudy of the Reinfusion of Enriched Progenitor Cells and Infarct Remodeling in Acute Myocardial Infarction (REPAIR-AMI) trial. Circulation 2007;116:366-374 (Pubitemid 47196542)
60. Sasaki K, Heeschen C, Aicher A, Ziebart T, Honold J, Urbich C et al. Ex vivo pretreatment of bone marrow mononuclear cells with endothelial NO synthase enhancer AVE9488 enhances their functional activity for cell therapy. Proc Natl Acad Sci U S A 2006;103:14537-14541 (Pubitemid 44484785)
61. Hofmann M, Wollert KC, Meyer GP, Menke A, Arseniev L, Hertenstein B et al. Monitoring of bone marrow cell homing into the infarcted human myocardium. Circulation 2005;111:2198-2202 (Pubitemid 40632435)
62. Dimmeler S, Burchfield J, Zeiher AM. Cell-based therapy of myocardial infarction. Arterioscler Thromb Vasc Biol 2008;28:208-216