Upregulation of MMP-13 via Runx2 in the stromal cell of Giant Cell Tumor of Bone

Bone

Volumn 45, Issue 2, 2009, Pages 377-386

  Mak, Isabella W Y ^a,b   Cowan, Robert W ^a   Popovic, Snezana ^c   Colterjohn, Nigel ^a,b   Singh, Gurmit ^a,b   Ghert, Michelle ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b JURAVINSKI CANCER CENTRE   (Canada)

^c HAMILTON HEALTH SCIENCES   (Canada)

Author keywords

Cytokines; Giant Cell Tumor (GCT); Matrix metalloprotease MMP 13; Runx2 transcription factor; Signaling pathways

Indexed keywords

COLLAGENASE 3; INTERLEUKIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RUNX2; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL STIMULATION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; ORTHOPEDIC SURGERY; OSTEOCLASTOMA; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STROMA CELL;

CORE BINDING FACTOR ALPHA 1 SUBUNIT; CULTURE MEDIA, CONDITIONED; ENZYME INDUCTION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GIANT CELL TUMOR OF BONE; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 2; PROTEIN KINASE INHIBITORS; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STROMAL CELLS; UP-REGULATION;

EID: 67649641789     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.04.253     Document Type: Article

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