In vivo imaging of autologous islet grafts in the liver and under the kidney capsule in non-human primates

Transplantation

Volumn 87, Issue 11, 2009, Pages 1659-1666

  Moore, Anna ^a   Medarova, Zdravka ^a   Vallabhajosyula, Prashanth ^a   Tena, Aseda ^a   Evgenov, Natalia ^a   Pantazopoulos, Pamela ^a   Tchipashvili, Vaja ^b   Weir, Gordon ^b   Sachs, David ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Feridex; Islet; Islet labeling; Islet transplant; MRI; Non human primate

Indexed keywords

CONTRAST MEDIUM; SUPERPARAMAGNETIC IRON OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GRAFT SURVIVAL; KIDNEY CAPSULE; LIVER PARENCHYMA; LIVER TRANSPLANTATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PANCREAS ISLET TRANSPLANTATION; PAPIO HAMADRYAS; PRIMATE; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CONTRAST MEDIA; INSULIN; IRON; ISLETS OF LANGERHANS TRANSPLANTATION; KIDNEY; LIVER TRANSPLANTATION; MAGNETIC RESONANCE IMAGING; OXIDES; PANCREATECTOMY; PAPIO; SUBRENAL CAPSULE ASSAY; TRANSPLANTATION, AUTOLOGOUS; TRANSPLANTATION, HETEROLOGOUS;

EID: 67649595485     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3181a5cbc0     Document Type: Article

References (31)

1. Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000; 343: 230.
2. Ryan EA, Lakey JR, Rajotte RV, et al. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes2001; 50: 710.
3. Shapiro AM, Ricordi C, Hering BJ, et al. International trial of the Edmonton protocol for islet transplantation. N Engl J Med 2006; 355: 1318.
4. Evgenov NV, Medarova Z, Dai G, et al. In vivo imaging of islet transplantation. Nat Med 2006; 12: 144.
5. Medarova Z, Evgenov NV, Dai G, et al. In vivo multimodal imaging of transplanted pancreatic islets. Nat Protoc 2006; 1: 429.
6. Evgenov NV, Medarova Z, Pratt J, et al. In vivo imaging of immune rejection in transplanted pancreatic islets. Diabetes 2006; 55: 2419.
7. Tai JH, Foster P, Rosales A, et al. Imaging islets labeled with magnetic nanoparticles at 1.5 Tesla. Diabetes 2006; 55: 2931.
8. Koulmanda M, Smith RN, Qipo A, et al. Prolonged survival of allogeneic islets in cynomolgus monkeys after short-term anti-CD154-based therapy: Nonimmunologic graft failure? Am J Transplant 2006; 6: 687.
9. Fischl B, Sereno MI, Dale AM. Cortical surface-based analysis. II. Inflation, flattening, and a surface-based coordinate system. Neuroimage1999; 9: 195.
10. Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage 1999; 9: 179.
11. Eich T, Eriksson O, Lundgren T. Visualization of early engraftment in clinical islet transplantation by positron-emission tomography. N Engl J Med 2007; 356: 2754.
12. Eich T, Eriksson O, Sundin A, et al. Positron emission tomography: A real-time tool to quantify early islet engraftment in a preclinical large animal model. Transplantation 2007; 84: 893.
13. Fowler M, Virostko J, Chen Z, et al. Assessment of pancreatic islet mass after islet transplantation using in vivo bioluminescence imaging. Transplantation 2005; 79: 768.
14. Lu Y, Dang H, Middleton B, et al. Long-term monitoring of transplanted islets using positron emission tomography. Mol Ther 2006; 14: 851.
15. Lu Y, Dang H, Middleton B, et al. Repetitive microPET imaging of implanted human islets in mice. Imaging the pancreatic beta cell. Bethesda, MD, 2003.
16. Lu Y, Dang H, Middleton B, et al. Bioluminescent monitoring of islet graft survival after transplantation. Mol Ther 2004; 9: 428.
17. Barnett BP, Arepally A, Karmarkar PV, et al. Magnetic resonanceguided, real-time targeted delivery and imaging of magnetocapsules immunoprotecting pancreatic islet cells. Nat Med 2007; 13: 986.
18. Biancone L, Crich SG, Cantaluppi V, et al. Magnetic resonance imaging of gadolinium-labeled pancreatic islets for experimental transplantation. NMR Biomed 2007; 20: 40.
19. Chen X, Zhang X, Larson CS, et al. In vivo bioluminescence imaging of transplanted islets and early detection of graft rejection. Transplantation2006; 81: 1421.
20. de Vries IJ, Lesterhuis WJ, Barentsz JO, et al. Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol 2005; 23: 1407.
21. Zhu J, Zhou L, Xing Wu F. Tracking neural stem cells in patients with brain trauma. N Engl J Med 2006; 355: 2376.
22. Medarova Z, Kumar M, Ng SW, et al. Multifunctional magnetic nanocarriers for image-tagged SiRNA delivery to intact pancreatic islets. Transplantation 2008; 86: 1170.
23. Jirak D, Kriz J, Herynek V, et al. MRI of transplanted pancreatic islets. Magn Reson Med 2004; 52: 1228.
24. Evgenov NV, Pratt J, Pantazopoulos P, et al. Effects of glucose toxicity and islet purity on in vivo magnetic resonance imaging of transplanted pancreatic islets. Transplantation 2008; 85: 1091.
25. Toso C, Vallee JP, Morel P, et al. Clinical magnetic resonance imaging of pancreatic islet grafts after iron nanoparticle labeling. Am J Transplant2008; 8: 701.
26. Hendrick R. Image contrast and noise [ed. 3]. St. Louis, Mosby 1999.
27. Cunningham PM, Law M, Schweitzer ME. High-field MRI. Orthop Clin North Am 2006; 37: 321.
28. Hu X, Norris DG. Advances in high-field magnetic resonance imaging. Annu Rev Biomed Eng 2004; 6: 157.
29. Tanenbaum LN. Clinical 3T MR imaging: Mastering the challenges. Magn Reson Imaging Clin N Am 2006; 14: 1.
30. Merkle EM, Dale BM. Abdominal MRI at 3.0 T: The basics revisited. AJR Am J Roentgenol 2006; 186: 1524.
31. Magee T, Shapiro M, Williams D. Comparison of high-field-strength versus low-field-strength MRI of the shoulder. AJR Am J Roentgenol2003; 181: 1211.