메뉴 건너뛰기




Volumn 18, Issue 10, 2008, Pages 1107-1110

Therapeutic neuronal stem cells: Patents at the forefront

Author keywords

Cellular therapy; Central nervous system; Clinical trial; Neural stem cells; Neurodegenerative diseases; Neurogenesis; Regeneration

Indexed keywords

BETA GALACTOSIDASE; COLLAGENASE; CYSTATIN C; FIBROBLAST GROWTH FACTOR 2; GREEN FLUORESCENT PROTEIN; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 56349133647     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.18.10.1107     Document Type: Editorial
Times cited : (7)

References (37)
  • 1
    • 0030894092 scopus 로고    scopus 로고
    • Stem cells in the central nervous system
    • McKay R. Stem cells in the central nervous system. Science 1997;276:66-71
    • (1997) Science , vol.276 , pp. 66-71
    • McKay, R.1
  • 3
    • 33847629581 scopus 로고    scopus 로고
    • Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension
    • Curtis MA, Kam M, Nannmark U, et al. Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension. Science 2007;315:1243-9
    • (2007) Science , vol.315 , pp. 1243-1249
    • Curtis, M.A.1    Kam, M.2    Nannmark, U.3
  • 4
    • 33845971534 scopus 로고    scopus 로고
    • Neural progenitor and stem cells in the adult central nervous system
    • Taupin P. Neural progenitor and stem cells in the adult central nervous system. Ann Acad Med Singapore 2006;35:814-7
    • (2006) Ann Acad Med Singapore , vol.35 , pp. 814-817
    • Taupin, P.1
  • 5
    • 56349132567 scopus 로고    scopus 로고
    • Weiss S, Reynolds B. Novel growth factor-responsive progenitor cells which can be proliferated in vitro. WO/1993/001275; 1993
    • Weiss S, Reynolds B. Novel growth factor-responsive progenitor cells which can be proliferated in vitro. WO/1993/001275; 1993
  • 6
    • 56349086355 scopus 로고    scopus 로고
    • Weiss S, Reynolds BA, Van Der Kooy D, et al. In situ modification and manipulation of stem cells of the central nervous system. WO/1995/ 013364; 1995
    • Weiss S, Reynolds BA, Van Der Kooy D, et al. In situ modification and manipulation of stem cells of the central nervous system. WO/1995/ 013364; 1995
  • 7
    • 56349165510 scopus 로고    scopus 로고
    • Weiss S, Reynolds B. In vitro induction of dopaminergic cells. WO/1996/ 015224; 1996
    • Weiss S, Reynolds B. In vitro induction of dopaminergic cells. WO/1996/ 015224; 1996
  • 8
    • 56349154792 scopus 로고    scopus 로고
    • Weiss S, Reynolds B. Regulation of neural stem cell proliferation. WO/ 1996/015226; 1996
    • Weiss S, Reynolds B. Regulation of neural stem cell proliferation. WO/ 1996/015226; 1996
  • 9
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds BA, Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992;255:1707-10
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 10
    • 0026526516 scopus 로고
    • A multiporent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes
    • Reynolds BA, Tetzlaff W, Weiss S. A multiporent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. J Neurosci 1992;12:4565-74
    • (1992) J Neurosci , vol.12 , pp. 4565-4574
    • Reynolds, B.A.1    Tetzlaff, W.2    Weiss, S.3
  • 11
    • 0035799605 scopus 로고    scopus 로고
    • Cell culture. Progenitor cells from human brain after death
    • Palmer TD, Schwartz PH, Taupin P, et al. Cell culture. Progenitor cells from human brain after death. Nature 2001;411:42-3
    • (2001) Nature , vol.411 , pp. 42-43
    • Palmer, T.D.1    Schwartz, P.H.2    Taupin, P.3
  • 12
    • 56349112677 scopus 로고    scopus 로고
    • Palmer TD, Gage FH, Schwartz PH, Taupin PJ. Postmortem stem cells. WO/ 2002/036749; 2002
    • Palmer TD, Gage FH, Schwartz PH, Taupin PJ. Postmortem stem cells. WO/ 2002/036749; 2002
  • 13
    • 56349092757 scopus 로고    scopus 로고
    • Uchida N. Use of collagenase in the preparation of neural stem cell cultures. WO/2000/050572; 2000
    • Uchida N. Use of collagenase in the preparation of neural stem cell cultures. WO/2000/050572; 2000
  • 14
    • 56349098039 scopus 로고    scopus 로고
    • Gage FH, Taupin PJ, Ray. Co-factors for trophic factors, and methods of use thereof. JWO/2000/033791; 2000
    • Gage FH, Taupin PJ, Ray. Co-factors for trophic factors, and methods of use thereof. JWO/2000/033791; 2000
  • 15
    • 0033635021 scopus 로고    scopus 로고
    • FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor
    • Taupin P, Ray J, Fischer WH, et al. FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor. Neuron 2000;28:385-97
    • (2000) Neuron , vol.28 , pp. 385-397
    • Taupin, P.1    Ray, J.2    Fischer, W.H.3
  • 16
    • 0033593654 scopus 로고    scopus 로고
    • Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo
    • Bjornson CR, Rietze RL, Reynolds BA, et al. Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science 1999;283:534-7
    • (1999) Science , vol.283 , pp. 534-537
    • Bjornson, C.R.1    Rietze, R.L.2    Reynolds, B.A.3
  • 17
    • 0034531907 scopus 로고    scopus 로고
    • From marrow to brain: Expression of neuronal phenotypes in adult mice
    • Brazelton TR, Rossi FM, Keshet GI, et al. From marrow to brain: expression of neuronal phenotypes in adult mice. Science 2000;290:1775-9
    • (2000) Science , vol.290 , pp. 1775-1779
    • Brazelton, T.R.1    Rossi, F.M.2    Keshet, G.I.3
  • 18
    • 0034532106 scopus 로고    scopus 로고
    • Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow
    • Mezey E, Chandross KJ, Harta G, et al. Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science 2000;290:1779-82
    • (2000) Science , vol.290 , pp. 1779-1782
    • Mezey, E.1    Chandross, K.J.2    Harta, G.3
  • 19
    • 0034848122 scopus 로고    scopus 로고
    • Isolation of multipotent adult stem cells from the dermis of mammalian skin
    • Toma JG, Akhavan M, Fernandes KJ, et al. Isolation of multipotent adult stem cells from the dermis of mammalian skin. Nat Cell Biol 2001;3:778-84
    • (2001) Nat Cell Biol , vol.3 , pp. 778-784
    • Toma, J.G.1    Akhavan, M.2    Fernandes, K.J.3
  • 20
    • 0036129434 scopus 로고    scopus 로고
    • Are somatic stem cells pluripotent or lineage-restricted?
    • D'Amour KA, Gage FH. Are somatic stem cells pluripotent or lineage-restricted? Nat Med 2002;8:213-4
    • (2002) Nat Med , vol.8 , pp. 213-214
    • D'Amour, K.A.1    Gage, F.H.2
  • 21
    • 56349129065 scopus 로고    scopus 로고
    • Bjornson CR, Rietze RT, Reynolds BA, Vescovi AL. Generation of hematopoietic cells from multipotent neural stem cells. WO/1999/016863; 1999
    • Bjornson CR, Rietze RT, Reynolds BA, Vescovi AL. Generation of hematopoietic cells from multipotent neural stem cells. WO/1999/016863; 1999
  • 22
    • 56349115238 scopus 로고    scopus 로고
    • Lagasse F. Weissman EL. Pluripotential stem cells. WO/2001/071016; 2001
    • Lagasse F. Weissman EL. Pluripotential stem cells. WO/2001/071016; 2001
  • 23
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-76
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 24
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007;318:1917-20
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 25
    • 0029610078 scopus 로고
    • Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain
    • Gage FH, Coates PW, Palmer TD, et al. Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc Natl Acad Sci USA 1995;92:11879-83
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11879-11883
    • Gage, F.H.1    Coates, P.W.2    Palmer, T.D.3
  • 26
    • 56349106329 scopus 로고    scopus 로고
    • Weiss S, Reynolds B, Hammang JP, Baetge EE. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny. US-05,750,376; 1998
    • Weiss S, Reynolds B, Hammang JP, Baetge EE. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny. US-05,750,376; 1998
  • 27
    • 9344260848 scopus 로고    scopus 로고
    • Intracerebral transplantation of adult mouse neural progenitor cells into the Niemann-Pick-A mouse leads to a marked decrease in lysosomal storage pathology
    • Shihabuddin LS, Numan S, Huff MR, et al. Intracerebral transplantation of adult mouse neural progenitor cells into the Niemann-Pick-A mouse leads to a marked decrease in lysosomal storage pathology. J Neurosci 2004;24:10642-51
    • (2004) J Neurosci , vol.24 , pp. 10642-10651
    • Shihabuddin, L.S.1    Numan, S.2    Huff, M.R.3
  • 28
    • 56349167432 scopus 로고    scopus 로고
    • Uchida N, Jacobs Y, Tamaki S. Methods for the treatment of lysosomal storage disorders. WO/2006/074387; 2006
    • Uchida N, Jacobs Y, Tamaki S. Methods for the treatment of lysosomal storage disorders. WO/2006/074387; 2006
  • 29
    • 33645701362 scopus 로고    scopus 로고
    • HuCNS-SC (StemCells)
    • Taupin P. HuCNS-SC (StemCells). Curr Opin Mol Ther 2006;8:156-63
    • (2006) Curr Opin Mol Ther , vol.8 , pp. 156-163
    • Taupin, P.1
  • 30
    • 56349160935 scopus 로고    scopus 로고
    • StemCells, Inc. website. Available from
    • StemCells, Inc. website. Available from: http://www.stemcellsinc.com
  • 31
    • 56349136701 scopus 로고    scopus 로고
    • Available from
    • NeuroGeneration website. Available from: http://www.neurogeneration.com
    • NeuroGeneration website
  • 32
    • 0036522968 scopus 로고    scopus 로고
    • Adult rodent neurogenic regions: The ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors
    • Seaberg RM, van der Kooy D. Adult rodent neurogenic regions: the ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors. J Neurosci 2002;22:1784-93
    • (2002) J Neurosci , vol.22 , pp. 1784-1793
    • Seaberg, R.M.1    van der Kooy, D.2
  • 33
    • 33644823573 scopus 로고    scopus 로고
    • Differential properties of adult rat and mouse brain-derived neural stem/progenitor cells
    • Ray J, Gage FH. Differential properties of adult rat and mouse brain-derived neural stem/progenitor cells. Mol Cell Neurosci 2006;31:560-73
    • (2006) Mol Cell Neurosci , vol.31 , pp. 560-573
    • Ray, J.1    Gage, F.H.2
  • 34
    • 18244382560 scopus 로고    scopus 로고
    • Neural stem cells and neurospheres-re-evaluating the relationship
    • Reynolds BA, Rietze RL. Neural stem cells and neurospheres-re-evaluating the relationship. Nat Methods 2005;2:333-6
    • (2005) Nat Methods , vol.2 , pp. 333-336
    • Reynolds, B.A.1    Rietze, R.L.2
  • 35
    • 56349140477 scopus 로고    scopus 로고
    • Buck DW, Uchida N, Weissman I. Enriched central nervous system cell populations. WO/2000/047762; 2000
    • Buck DW, Uchida N, Weissman I. Enriched central nervous system cell populations. WO/2000/047762; 2000
  • 36
    • 56349096669 scopus 로고    scopus 로고
    • Uchida N, Capela A. Enriched central nervous system stem cells and progenitor cell populations, and methods for identifying, isolating and enriching for such populations. WO/2004/020597; 2004
    • Uchida N, Capela A. Enriched central nervous system stem cells and progenitor cell populations, and methods for identifying, isolating and enriching for such populations. WO/2004/020597; 2004
  • 37
    • 56349150723 scopus 로고    scopus 로고
    • Uchida N. Capela A. Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations. US-7,381,561; 2008
    • Uchida N. Capela A. Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations. US-7,381,561; 2008


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.