-
1
-
-
33644875101
-
The expression of the ubiquitin ligase subunit Cks1 in human breast cancer
-
Slotky M, Shapira M, Ben-Izhak O, et al: The expression of the ubiquitin ligase subunit Cks1 in human breast cancer. Breast Cancer Res 7: R737-R744, 2005.
-
(2005)
Breast Cancer Res
, vol.7
-
-
Slotky, M.1
Shapira, M.2
Ben-Izhak, O.3
-
2
-
-
46049116296
-
Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death
-
Lan Y, Zhang Y, Wang J, et al: Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death. Int J Cancer 123: 543-551, 2008.
-
(2008)
Int J Cancer
, vol.123
, pp. 543-551
-
-
Lan, Y.1
Zhang, Y.2
Wang, J.3
-
3
-
-
0344211819
-
High expression of Cks1 in human non-small cell lung carcinomas
-
Inui N, Kitagawa K, Miwa S, et al: High expression of Cks1 in human non-small cell lung carcinomas. Biochem Biophys Res Commun 303: 978-984, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 978-984
-
-
Inui, N.1
Kitagawa, K.2
Miwa, S.3
-
4
-
-
15744382959
-
The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma
-
Shapira M, Ben-Izhak O, Linn S, et al: The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma. Cancer 103: 1336-1346, 2005.
-
(2005)
Cancer
, vol.103
, pp. 1336-1346
-
-
Shapira, M.1
Ben-Izhak, O.2
Linn, S.3
-
5
-
-
0029024015
-
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
-
Pagano M, Tam SW, Theodoras AM, et al: Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 269: 682-685, 1995.
-
(1995)
Science
, vol.269
, pp. 682-685
-
-
Pagano, M.1
Tam, S.W.2
Theodoras, A.M.3
-
6
-
-
0033176887
-
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
-
Carrano AC, Eytan E, Hershko A and Pagano M: SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat Cell Biol 1: 193-199, 1999.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 193-199
-
-
Carrano, A.C.1
Eytan, E.2
Hershko, A.3
Pagano, M.4
-
7
-
-
0035954432
-
Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression
-
Carrano AC and Pagano M: Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression. J Cell Biol 153: 1381-1390, 2001.
-
(2001)
J Cell Biol
, vol.153
, pp. 1381-1390
-
-
Carrano, A.C.1
Pagano, M.2
-
8
-
-
0035092687
-
The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27
-
Ganoth D, Bornstein G, Ko TK, et al: The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nat Cell Biol 3: 321-324, 2001.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 321-324
-
-
Ganoth, D.1
Bornstein, G.2
Ko, T.K.3
-
9
-
-
0035265829
-
A CDK-independent function of mammalian Cks1: Targeting of SCF(Skp2) to the CDK inhibitor p27Kip1
-
Spruck C, Strohmaier H, Watson M, et al: A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1. Mol Cell 7: 639-650, 2001.
-
(2001)
Mol Cell
, vol.7
, pp. 639-650
-
-
Spruck, C.1
Strohmaier, H.2
Watson, M.3
-
10
-
-
15844384256
-
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice
-
Fero ML, Rivkin M, Tasch M, et al: A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice. Cell 85: 733-744, 1996.
-
(1996)
Cell
, vol.85
, pp. 733-744
-
-
Fero, M.L.1
Rivkin, M.2
Tasch, M.3
-
11
-
-
0032511848
-
The murine gene p27Kip1 is haplo-insufficient for tumour suppression
-
Fero ML, Randel E, Gurley KE, et al: The murine gene p27Kip1 is haplo-insufficient for tumour suppression. Nature 396: 177-180, 1998.
-
(1998)
Nature
, vol.396
, pp. 177-180
-
-
Fero, M.L.1
Randel, E.2
Gurley, K.E.3
-
12
-
-
16944363001
-
Decreased levels of the cell-cycle inhibitor p27Kip1 protein: Prognostic implications in primary breast cancer
-
Catzavelos C, Bhattacharya N, Ung YC, et al: Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer. Nat Med 3: 227-230, 1997.
-
(1997)
Nat Med
, vol.3
, pp. 227-230
-
-
Catzavelos, C.1
Bhattacharya, N.2
Ung, Y.C.3
-
13
-
-
0031048716
-
Expression of cellcycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
-
Porter PL, Malone KE, Heagerty PJ, et al: Expression of cellcycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nat Med 3: 222-225, 1997.
-
(1997)
Nat Med
, vol.3
, pp. 222-225
-
-
Porter, P.L.1
Malone, K.E.2
Heagerty, P.J.3
-
14
-
-
0030894787
-
The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas
-
Tan P, Cady B, Wanner M, et al: The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas. Cancer Res 57: 1259-1263, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 1259-1263
-
-
Tan, P.1
Cady, B.2
Wanner, M.3
-
15
-
-
0030947356
-
High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: Inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers
-
Fredersdorf S, Burns J, Milne AM, et al: High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers. Proc Natl Acad Sci USA 94: 6380-6385, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6380-6385
-
-
Fredersdorf, S.1
Burns, J.2
Milne, A.M.3
-
17
-
-
4344688268
-
Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT- transgenic mice: Correlation to human disease
-
Qiu TH, Chandramouli GV, Hunter KW, et al: Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT- transgenic mice: correlation to human disease. Cancer Res 64: 5973-5981, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 5973-5981
-
-
Qiu, T.H.1
Chandramouli, G.V.2
Hunter, K.W.3
-
19
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl MW: A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45, 2001.
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Pfaffl, M.W.1
-
20
-
-
0027954475
-
Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice
-
Guy CT, Muthuswamy SK, Cardiff RD, et al: Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice. Genes Dev 8: 23-32, 1994.
-
(1994)
Genes Dev
, vol.8
, pp. 23-32
-
-
Guy, C.T.1
Muthuswamy, S.K.2
Cardiff, R.D.3
-
21
-
-
0031948388
-
Requirement for both Shc and phosphatidylinositol 3' kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis
-
Webster MA, Hutchinson JN, Rauh MJ, et al: Requirement for both Shc and phosphatidylinositol 3' kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis. Mol Cell Biol 18: 2344-2359, 1998.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2344-2359
-
-
Webster, M.A.1
Hutchinson, J.N.2
Rauh, M.J.3
-
22
-
-
0035890383
-
Transgenic polyoma middle-T mice model premalignant mammary disease
-
Maglione JE, Moghanaki D, Young LJ, et al: Transgenic polyoma middle-T mice model premalignant mammary disease. Cancer Res 61: 8298-8305, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 8298-8305
-
-
Maglione, J.E.1
Moghanaki, D.2
Young, L.J.3
-
23
-
-
0037367204
-
Estradiol promotes growth and angiogenesis in polyoma middle T transgenic mouse mammary tumor explants
-
Dabrosin C, Palmer K, Muller WJ and Gauldie J: Estradiol promotes growth and angiogenesis in polyoma middle T transgenic mouse mammary tumor explants. Breast Cancer Res Treat 78: 1-6, 2003.
-
(2003)
Breast Cancer Res Treat
, vol.78
, pp. 1-6
-
-
Dabrosin, C.1
Palmer, K.2
Muller, W.J.3
Gauldie, J.4
-
24
-
-
0036710683
-
ErbB-2-induced mammary tumor growth: The role of cyclin D1 and p27Kip1
-
Hulit J, Lee RJ, Russell RG and Pestell RG: ErbB-2-induced mammary tumor growth: the role of cyclin D1 and p27Kip1. Biochem Pharmacol 64: 827-836, 2002.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 827-836
-
-
Hulit, J.1
Lee, R.J.2
Russell, R.G.3
Pestell, R.G.4
-
25
-
-
0037325853
-
Deregulated degradation of the cdk inhibitor p27 and malignant transformation
-
Bloom J and Pagano M: Deregulated degradation of the cdk inhibitor p27 and malignant transformation. Semin Cancer Biol 13: 41-47, 2003.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 41-47
-
-
Bloom, J.1
Pagano, M.2
-
26
-
-
37049006067
-
Cks1 regulates cdk1 expression: A novel role during mitotic entry in breast cancer cells
-
Westbrook L, Manuvakhova M, Kern FG, et al: Cks1 regulates cdk1 expression: a novel role during mitotic entry in breast cancer cells. Cancer Res 67: 11393-11401, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 11393-11401
-
-
Westbrook, L.1
Manuvakhova, M.2
Kern, F.G.3
-
27
-
-
0022573987
-
The fission yeast cell cycle control gene cdc2: Isolation of a sequence suc1 that suppresses cdc2 mutant function
-
Hayles J, Beach D, Durkacz B and Nurse P: The fission yeast cell cycle control gene cdc2: isolation of a sequence suc1 that suppresses cdc2 mutant function. Mol Gen Genet 202: 291-293, 1986.
-
(1986)
Mol Gen Genet
, vol.202
, pp. 291-293
-
-
Hayles, J.1
Beach, D.2
Durkacz, B.3
Nurse, P.4
-
28
-
-
0024553955
-
The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex
-
Hadwiger JA, Wittenberg C, Mendenhall MD and Reed SI: The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex. Mol Cell Biol 9: 2034-2041, 1989.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 2034-2041
-
-
Hadwiger, J.A.1
Wittenberg, C.2
Mendenhall, M.D.3
Reed, S.I.4
-
29
-
-
0023446949
-
p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase
-
Brizuela L, Draetta G and Beach D: p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase. EMBO J 6: 3507-3514, 1987.
-
(1987)
EMBO J
, vol.6
, pp. 3507-3514
-
-
Brizuela, L.1
Draetta, G.2
Beach, D.3
-
30
-
-
0034704870
-
Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells
-
Neve RM, Sutterluty H, Pullen N, et al: Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells. Oncogene 19: 1647-1656, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 1647-1656
-
-
Neve, R.M.1
Sutterluty, H.2
Pullen, N.3
-
31
-
-
0034092911
-
Regulation of the cdk inhibitor p27 and its deregulation in cancer
-
Slingerland J and Pagano M: Regulation of the cdk inhibitor p27 and its deregulation in cancer. J Cell Physiol 183: 10-17, 2000.
-
(2000)
J Cell Physiol
, vol.183
, pp. 10-17
-
-
Slingerland, J.1
Pagano, M.2
-
32
-
-
33845653943
-
The possible mechanism of enhanced carcinogenesis induced by genotoxic carcinogens in rasH2 mice
-
Okamura M, Unami A, Moto M, et al: The possible mechanism of enhanced carcinogenesis induced by genotoxic carcinogens in rasH2 mice. Cancer Lett 245: 321-330, 2007.
-
(2007)
Cancer Lett
, vol.245
, pp. 321-330
-
-
Okamura, M.1
Unami, A.2
Moto, M.3
-
33
-
-
0033559264
-
The p21(Cip1) and p27(Kip1) CDK inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
-
Cheng M, Olivier P, Diehl JA, et al: The p21(Cip1) and p27(Kip1) CDK inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J 18: 1571-1583, 1999.
-
(1999)
EMBO J
, vol.18
, pp. 1571-1583
-
-
Cheng, M.1
Olivier, P.2
Diehl, J.A.3
-
34
-
-
0033601171
-
The xenopus Suc1/Cks protein promotes the phosphorylation of G(2)/M regulators
-
Patra D, Wang SX, Kumagai A and Dunphy WG: The xenopus Suc1/Cks protein promotes the phosphorylation of G(2)/M regulators. J Biol Chem 274: 36839-36842, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 36839-36842
-
-
Patra, D.1
Wang, S.X.2
Kumagai, A.3
Dunphy, W.G.4
-
35
-
-
0033854055
-
Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast
-
Reynard GJ, Reynolds W, Verma R and Deshaies RJ: Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast. Mol Cell Biol 20: 5858-5864, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5858-5864
-
-
Reynard, G.J.1
Reynolds, W.2
Verma, R.3
Deshaies, R.J.4
-
36
-
-
0031835655
-
Cyclin-stimulated binding of Cks proteins to cyclin-dependent kinases
-
Egan EA and Solomon MJ: Cyclin-stimulated binding of Cks proteins to cyclin-dependent kinases. Mol Cell Biol 18: 3659-3667, 1998.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3659-3667
-
-
Egan, E.A.1
Solomon, M.J.2
-
37
-
-
0032529162
-
Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase-promoting complex at mitosis
-
Patra D and Dunphy WG: Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase-promoting complex at mitosis. Genes Dev 12: 2549-2559, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 2549-2559
-
-
Patra, D.1
Dunphy, W.G.2
-
38
-
-
0029784224
-
Xe-p9, a Xenopus Suc1/Cks homolog, has multiple essential roles in cell cycle control
-
Patra D and Dunphy WG: Xe-p9, a Xenopus Suc1/Cks homolog, has multiple essential roles in cell cycle control. Genes Dev 10: 1503-1515, 1996.
-
(1996)
Genes Dev
, vol.10
, pp. 1503-1515
-
-
Patra, D.1
Dunphy, W.G.2
-
39
-
-
0042304165
-
Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast
-
Morris MC, Kaiser P, Rudyak S, et al: Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast. Nature 424: 1009-1013, 2003.
-
(2003)
Nature
, vol.424
, pp. 1009-1013
-
-
Morris, M.C.1
Kaiser, P.2
Rudyak, S.3
-
40
-
-
0037112174
-
The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(Skp2)
-
Tedesco D, Lukas J and Reed SI: The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(Skp2). Genes Dev 16: 2946-2957, 2002.
-
(2002)
Genes Dev
, vol.16
, pp. 2946-2957
-
-
Tedesco, D.1
Lukas, J.2
Reed, S.I.3
-
41
-
-
1442284076
-
Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling
-
Wang W, Ungermannova D, Jin J, et al: Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling. Oncogene 23: 1064-1075, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 1064-1075
-
-
Wang, W.1
Ungermannova, D.2
Jin, J.3
-
42
-
-
0142135033
-
Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway
-
Foster JS, Fernando RI, Ishida N, et al: Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway. J Biol Chem 278: 41355-41366, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 41355-41366
-
-
Foster, J.S.1
Fernando, R.I.2
Ishida, N.3
-
43
-
-
0036733716
-
Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer
-
Signoretti S, Di Marcotullio L, Richardson A, et al: Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer. J Clin Invest 110: 633-641, 2002.
-
(2002)
J Clin Invest
, vol.110
, pp. 633-641
-
-
Signoretti, S.1
Di Marcotullio, L.2
Richardson, A.3
-
44
-
-
0036645678
-
A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression
-
Boehm M, Yoshimoto T, Crook MF, et al: A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression. EMBO J 21: 3390-3401, 2002.
-
(2002)
EMBO J
, vol.21
, pp. 3390-3401
-
-
Boehm, M.1
Yoshimoto, T.2
Crook, M.F.3
-
45
-
-
18644370396
-
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/ Akt-mediated phosphorylation in breast cancer
-
Viglietto G, Motti ML, Bruni P, et al: Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/ Akt-mediated phosphorylation in breast cancer. Nat Med 8: 1136-1144, 2002.
-
(2002)
Nat Med
, vol.8
, pp. 1136-1144
-
-
Viglietto, G.1
Motti, M.L.2
Bruni, P.3
-
46
-
-
0032437776
-
Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth
-
Grana X, Garriga J and Mayol X: Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth. Oncogene 17: 3365-3383, 1998.
-
(1998)
Oncogene
, vol.17
, pp. 3365-3383
-
-
Grana, X.1
Garriga, J.2
Mayol, X.3
-
47
-
-
0034623995
-
A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence
-
Carroll JS, Prall OW, Musgrove EA and Sutherland RL: A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence. J Biol Chem 275: 38221-38229, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 38221-38229
-
-
Carroll, J.S.1
Prall, O.W.2
Musgrove, E.A.3
Sutherland, R.L.4
|