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Volumn 50, Issue 33, 2009, Pages 4703-4705

A convenient synthesis of chiral amino acid derived 3,4-dihydro-2H-benzo[b][1,4]thiazines and antibiotic levofloxacin

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYL 1,4 BENZOXAZINE; AMINO ACID; AMINOALCOHOL; BENZOTHIAZINE DERIVATIVE; BENZOXAZINE DERIVATIVE; COPPER; ETHYLAMINE; LEVOFLOXACIN; THIOPHENOL DERIVATIVE; UNCLASSIFIED DRUG;

EID: 67649409027     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.05.104     Document Type: Article
Times cited : (66)

References (36)
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    • 1,4-Benzothiazines (a) as anti-inflammatory agents: (i) Lombardino, J. G.; Wiseman, E. H. Med. Res. Rev. 1982, 2, 127; (ii) Turk, C. F. J. Med. Chem. 1973, 16, 776. (b) as anti-hypertensive agents: (i) Prasad, R. N. J. Med. Chem. 1969, 12, 290; (ii) Cecchetti, V.; Fravolini, A.; Schiaffella, F.; DeRegis, M.; Orzalesi, G.; Volpato, I. Farmaco. Ed. Sci. 1983, 38, 35. (c) As anti-cancer agents: (i) Gupta, R. R.; Dev, P. K.; Sharma, M. L.; Rajoria, C. M.; Gupta, A.; Nyati, M. Anticancer Drugs 1993, 4, 589; (ii) Todorov, D. K.; Ilarionova, M. V.; Gupta, R. R.; Molnar, J.; Motohashi, N. Heterocycl. Commun. 1995, 1, 153. (d) as anti-fungal agent: (i) Schiaffella, F.; Macchiarulo, A.; Milanese, L.; Vecchiarell, A.; Fringuell. R. Bioorg. Med. Chem. 2006, 14, 5196; (ii) Fringuelli, R .; Schiaffella, F.; Bistoni, F.; Pitzurra, L.; Vecchiarelli, A. Bioorg. Med. Chem. 1998, 6, 103. (e) as anti-tumour agent: (i) Coughlin, S. A.; Danz, D. W.; Robinson, R. G.; Klingbeil, K. M.; Wentland, M. P.;
    • ATP-Channel Openers (i) Cecchetti, V.; Calderone, V.; Tabarrini, O.; Sabatini, S.; Filipponi, E.; Testai, L.; Spogli, R.; Martinotti, E.; Fravolini, A. J. Med. Chem. 2003, 46, 3670. (g) as anti-HIV agent: (i) Grandolini. G;, Perioli.L;, Ambarogi. V. Eur. J. Med. Chem. 1999, 34, 701; h) as CETP inhibitors: (i) Kuo, G.; Wang, A.; Rano, T.; Prouty, C.; Demarest, K. T.; Pelton, P. US patent, 2007, WO/134149.
  • 12
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    • Six membered Ring Systems
    • Comprehensive Organic Chemistry. Barton D., Ollis W.D., and Sammes P.G. (Eds), Pergamon Press, Oxford
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    • (1979) Heterocyclic Compounds , vol.4 , pp. 1092
    • Lanoquist, J.K.1
  • 14
    • 27244441344 scopus 로고
    • Gupta R.R. (Ed), Elsevier, Amsterdam, Neth
    • In: Gupta R.R. (Ed). Phenothiazines and 1,4-Benzothiazines: Chemical and Biomedical Aspects. Bioactive Molecules Vol. 4 (1988), Elsevier, Amsterdam, Neth
    • (1988) Bioactive Molecules , vol.4
  • 15
    • 84903913272 scopus 로고    scopus 로고
    • 1,4-Thiazines, 1,4-Benzothiazines, Phenothiazines and Related Compounds
    • Elsevier, Amsterdam, Neth (Part G (partial)/Part H)
    • Sainsbury M. 1,4-Thiazines, 1,4-Benzothiazines, Phenothiazines and Related Compounds. Rodd's Chemistry of Carbon Compounds. 2nd ed. Vol. 4 (1998), Elsevier, Amsterdam, Neth 575-608 (Part G (partial)/Part H)
    • (1998) Rodd's Chemistry of Carbon Compounds. 2nd ed. , vol.4 , pp. 575-608
    • Sainsbury, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.