Lower antibody response in chickens homozygous for the Mx resistant allele to avian influenza

Asian-Australasian Journal of Animal Sciences

Volumn 22, Issue 4, 2009, Pages 465-470

  Qu, L J ^a   Li, X Y ^a   Xu, G Y ^a   Ning, Z H ^a   Yang, N ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Antibody response; Avian influenza; Chick; Disease resistance; Mx gene

Indexed keywords

AVES; AVIAN INFLUENZA VIRUS; GALLUS GALLUS; ORTHOMYXOVIRIDAE;

EID: 67649343161     PISSN: 10112367     EISSN: None     Source Type: Journal    
DOI: 10.5713/ajas.2009.80338     Document Type: Article

References (37)

1. An, B. K., B. L. Cho, S. J. You, H. D. Paik, H. I. Chang, S. W. Kim, C. W. Yun and C. W. Kang. 2008. Growth performance and antibody response of broiler chicks fed yeast derived P- glucan and single-strain probiotics. Asian-Aust. J. Anim. Sci. 21:1027-1032.
2. Arnheiter, H. and O. Haller. 1983. Mx gene control of interferon action: different kinetics of the antiviral state against influenza virus and vesicular stomatitis virus. J. Virol. 47:626-630.
3. Bazzigher, L., A. Schwarz and P. Staeheli. 1993. No enhanced influenza virus resistance of murine and avian cells expressing cloned duck Mx protein. Virol. 195:100-112.
4. Berlin, S., L. Qu, X. Li, N. Yang and H. Ellegren. 2008. Positive diversifying selection in avian Mx genes. Immunogenetics 60:689-697.
5. Bernasconi, D., U. Schultz and P. Staeheli. 1995. The interferoninduced Mx protein of chickens lacks antiviral activity. J. Interferon Cytokine Res. 15:47-53.
6. Beuken, E., G Grauls, C. A. Bruggeman and C. Vink. 1999. The rat cytomegalovirus R32 gene encodes a virion-associated protein that elicits a strong humoral immune response in infected rats. J. Gen. Virol. 80 (Pt 10) :2719-2728.
7. Biozzi, G, D. Mouton, O. A. Sant'Anna, H. C. Passos, M. Gennari, M. H. Reis, V. C. Ferreira, A. M. Heumann, Y. Bouthillier, O. M. Ibanez, C. Stiffel and M. Siqueira. 1979. Genetics of immunoresponsiveness to natural antigens in the mouse. Curr. Top Microbiol. Immunol. 85:31-98.
8. Bucin, D., T. Lindholm and N. H. Persson. 1992. HLA-A region in highly sensitized patients: another immune response gene region. Exp. Clin. Immunogenet. 9:154-160.
9. Dalgaard, T. S., S. Hojsgaard, K. Skjodt and H. R. Juul-Madsen. 2003. Differences in chicken major histocompatibility complex (MHC) class Ialpha gene expression between Marek's diseaseresistant and -susceptible MHC haplotypes. Scand. J. Immunol. 57:135-143.
10. Flex, A., E. Gaetani, R. Pola, R. Santoliquido, F. Aloi, P. Papaleo, A. Dal Lago, E. Pola, M. Serricchio, P. Tondi and P. Pola. 2002. The -174 G/C polymorphism of the interleukin-6 gene promoter is associated with peripheral artery occlusive disease. Eur. J. Vase. Endovasc. Surg. 24:264-268.
11. Flohr, F., S. Schneider-Schaulies, O. Haller and G Kochs. 1999. The central interactive region of human MxA GTPase is involved in GTPase activation and interaction with viral target structures. FEBS Lett. 463:24-28.
12. Haller, O., M. Frese and G Kochs. 1998. Mx proteins: mediators of innate resistance to RNA viruses. Rev. Sci. Tech. 17:220- 230.
13. Hou, Z. C, G Y Xu and Z. Su. 2007. Purifying selection and positive selection on the myxovirus resistance gene in mammals and chickens. Gene. 396:188-195.
14. Jansa, S. A., B. L. Lundrigan and P. K. Tucker. 2003. Tests for positive selection on immune and reproductive genes in closely related species of the murine genus mus. J. Mol. Evol. 56:294-307.
15. Ko, J. H., A. Takada, T. Mitsuhashi, T. Agui and T. Watanabe. 2004. Native antiviral specificity of chicken Mx protein depends on amino acid variation at position 631. Anim. Genet. 35:119-122.
16. Ko, J. H., H. K. Jin, A. Asano, A. Takada, A. Ninomiya, H. Kida, H. Hokiyama, M. Ohara, M. Tsuzuki, M. Nishibori, M. Mizutani and T. Watanabe. 2002. Polymorphisms and the differential antiviral activity of the chicken Mx gene. Genome Res. 12:595-601.
17. Lee, S. H. and S. M. 2002. Vidal. Functional diversity of Mx proteins: variations on a theme of host resistance to infection. Genome Res. 12:527-530.
18. Leitner, G, Z. Uni, A. Cahaner, M. Gutman and E. D. Heller. 1992. Replicated divergent selection of broiler chickens for high or low early antibody response to Escherichia coli vaccination. Poult. Sci. 71:27-37.
19. Li, X. Y, L. J. Qu, J. F. Yao, L. J. Qu, J. F. Yao and N. Yang. 2006. Skewed allele frequencies of an Mx gene mutation with potential resistance to avian influenza virus in different chicken populations. Poult. Sci. 85:1327-1329.
20. McMichael, A. and J. Bell. 1991. HLA B27: a disease-associated immune response gene. Res. Immunol. 142:475-482.
21. O'Connell, M. J. and J. O. Mclnerney. 2005. Gamma chain receptor interleukins: evidence for positive selection driving the evolution of cell-to-cell communicators in the mammalian immune system. J. Mol. Evol. 61:608-619.
22. Pavlovic, J. and P. Staeheli. 1991. The antiviral potentials of Mx proteins. J. Interferon Res. 11:215-219.
23. Pevzner, I. Y, H. A. Stone and A. W. Nordskog. 1981b. Immune response and disease resistance in chickens. I. Selection for high and low titer to Salmonella pullorum antigen. Poult. Sci. 60:920-926.
24. Pevzner, I. Y, I. Kujdych and A. W. Nordskog. 1981a. Immune response and disease resistance in chickens. II. Marek's disease and immune response to GAT. Poult. Sci. 60:927-932.
25. Plant, K. P. and R. L. Thune. 2004. Cloning and characterisation of a channel catfish (Ictalurus punctatus) Mx gene. Fish Shellfish Immunol. 16:391-405.
26. Quere, P., C. Rivas, K. Ester, K., Novak and W. L. Ragland. 2005. Abundance of IFN-alpha and IFN-gamma mRNA in blood of resistant and susceptible chickens infected with Marek's disease virus (MDV) or vaccinated with turkey herpesvirus; and MDV inhibition of subsequent induction of IFN gene transcription. Arch. Virol. 150:507-519.
27. Rothman, J. H., C. K. Raymond, T. Gilbert, P. J. O'Hara and T. H. Stevens. 1990. A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting. Cell 61:1063-1074.
28. Rund, D., I. Azar and O. Shperling. 1999. A mutation in the promoter of the multidrug resistance gene (MDR1) in human hematological malignancies may contribute to the pathogenesis of resistant disease. Adv. Exp. Med. Biol. 457:71-75.
29. SAS-Institute., Version 8.2. Cary. 2001.
30. Siegel, P. B. and W. B. Gross. 1980. Production and persistence of antibodies in chicken to sheep erythrocytes, 1. Directional selection. Poult. Sci. 59:1-5.
31. Staeheli, P. 1990. Interferon-induced proteins and the antiviral state. Adv. Virus Res. 38:147-200.
32. Staeheli, P., Y. X. Yu, R. Grob and O. Haller. 1989. A doublestranded RNA-inducible fish gene homologous to the murine influenza virus resistance gene Mx. Mol. Cell Biol. 9:3117- 3121.
33. Steadham, E. M., S. J. Lamont, I. Kujdych and A. W. Nordskog. 1987. Association of Marek's disease with Ea-B and immune response genes in subline and F2 populations of the Iowa State SI Leghorn line. Poult. Sci. 66:571-575.
34. Vallender, E. J. and B. T. Lahn. 2004. Positive selection on the human genome. Hum. Mol. Genet. 13 Spec. No 2:R245-254.
35. van der Zijpp, A. J., K. Frankena and J. Boneschanscher. 1983. Genetic analysis of primary and secondary immune responses in the chicken. Poult. Sci. 62:565-572.
36. Wang, E. T., G Kodama, P. Baldi and R. K. Moyzis. 2006. Global landscape of recent inferred Darwinian selection for Homo sapiens. Proc. Natl. Acad. Sci. 103:135-140.
37. Weigend, S., N. Mielenz and S. J. Lamont. 1997. Application of a nonlinear regression function to evaluate the kinetics of antibody response to vaccines in chicken lines divergently selected for multitrait immune response. Poult. Sci. 76:1248- 1255.