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Volumn 27, Issue 33, 2009, Pages 4475-4482

Harnessing the unique local immunostimulatory properties of modified vaccinia Ankara (MVA) virus to generate superior tumor-specific immune responses and antitumor activity in a diversified prime and boost vaccine regimen

Author keywords

Carcinoembryonic antigen (CEA); Costimulation; Modified vaccinia Ankara (MVA); Vaccinia

Indexed keywords

B7 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CYTOKINE; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; VIRUS VECTOR;

EID: 67649340803     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.05.017     Document Type: Article
Times cited : (29)

References (49)
  • 1
    • 46849096064 scopus 로고    scopus 로고
    • Cancer vaccines: on the threshold of success
    • Emens L.A. Cancer vaccines: on the threshold of success. Expert Opin Emerg Drugs 13 June (2) (2008) 295-308
    • (2008) Expert Opin Emerg Drugs , vol.13 , Issue.June 2 , pp. 295-308
    • Emens, L.A.1
  • 2
    • 66749137687 scopus 로고    scopus 로고
    • Vaccination strategies and vaccine formulations for epidemic and pandemic influenza control
    • Kreijtz J.H., Osterhaus A.D., and Rimmelzwaan G.F. Vaccination strategies and vaccine formulations for epidemic and pandemic influenza control. Hum Vaccin 5 March (3) (2009)
    • (2009) Hum Vaccin , vol.5 , Issue.March 3
    • Kreijtz, J.H.1    Osterhaus, A.D.2    Rimmelzwaan, G.F.3
  • 3
    • 20444444975 scopus 로고    scopus 로고
    • Prime-boost immunisation strategies for tuberculosis
    • McShane H., and Hill A. Prime-boost immunisation strategies for tuberculosis. Microbes Infect 7 May (5-6) (2005) 962-967
    • (2005) Microbes Infect , vol.7 , Issue.May 5-6 , pp. 962-967
    • McShane, H.1    Hill, A.2
  • 4
    • 58149375456 scopus 로고    scopus 로고
    • Elite control of HIV infection: implications for vaccine design
    • Baker B.M., Block B.L., Rothchild A.C., and Walker B.D. Elite control of HIV infection: implications for vaccine design. Expert Opin Biol Ther 9 January (1) (2009) 55-69
    • (2009) Expert Opin Biol Ther , vol.9 , Issue.January 1 , pp. 55-69
    • Baker, B.M.1    Block, B.L.2    Rothchild, A.C.3    Walker, B.D.4
  • 5
    • 45949093410 scopus 로고    scopus 로고
    • Malaria vaccines: a toy for travelers or a tool for eradication?
    • Genton B. Malaria vaccines: a toy for travelers or a tool for eradication?. Expert Rev Vaccines 7 July (5) (2008) 597-611
    • (2008) Expert Rev Vaccines , vol.7 , Issue.July 5 , pp. 597-611
    • Genton, B.1
  • 6
    • 37349109250 scopus 로고    scopus 로고
    • Plasmid DNA- and messenger RNA-based anti-cancer vaccination
    • Weide B., Garbe C., Rammensee H.G., and Pascolo S. Plasmid DNA- and messenger RNA-based anti-cancer vaccination. Immunol Lett 115 January (1) (2008) 33-42
    • (2008) Immunol Lett , vol.115 , Issue.January 1 , pp. 33-42
    • Weide, B.1    Garbe, C.2    Rammensee, H.G.3    Pascolo, S.4
  • 7
    • 58149376077 scopus 로고    scopus 로고
    • Construction and characterization of an attenuated Listeria monocytogenes strain for clinical use in cancer immunotherapy
    • Wallecha A., Maciag P.C., Rivera S., Paterson Y., and Shahabi V. Construction and characterization of an attenuated Listeria monocytogenes strain for clinical use in cancer immunotherapy. Clin Vaccine Immunol 16 January (1) (2009) 96-103
    • (2009) Clin Vaccine Immunol , vol.16 , Issue.January 1 , pp. 96-103
    • Wallecha, A.1    Maciag, P.C.2    Rivera, S.3    Paterson, Y.4    Shahabi, V.5
  • 8
    • 45849104841 scopus 로고    scopus 로고
    • The poxvirus vectors MVA and NYVAC as gene delivery systems for vaccination against infectious diseases and cancer
    • Gomez C.E., Najera J.L., Krupa M., and Esteban M. The poxvirus vectors MVA and NYVAC as gene delivery systems for vaccination against infectious diseases and cancer. Curr Gene Ther 8 April (2) (2008) 97-120
    • (2008) Curr Gene Ther , vol.8 , Issue.April 2 , pp. 97-120
    • Gomez, C.E.1    Najera, J.L.2    Krupa, M.3    Esteban, M.4
  • 9
    • 48249091314 scopus 로고    scopus 로고
    • Vaccination with a recombinant Saccharomyces cerevisiae expressing a tumor antigen breaks immune tolerance and elicits therapeutic antitumor responses
    • Wansley E.K., Chakraborty M., Hance K.W., Bernstein M.B., Boehm A.L., Guo Z., et al. Vaccination with a recombinant Saccharomyces cerevisiae expressing a tumor antigen breaks immune tolerance and elicits therapeutic antitumor responses. Clin Cancer Res 14 July (13) (2008) 4316-4325
    • (2008) Clin Cancer Res , vol.14 , Issue.July 13 , pp. 4316-4325
    • Wansley, E.K.1    Chakraborty, M.2    Hance, K.W.3    Bernstein, M.B.4    Boehm, A.L.5    Guo, Z.6
  • 10
    • 34447136106 scopus 로고    scopus 로고
    • Cancer vaccines: moving beyond current paradigms
    • Schlom J., Arlen P.M., and Gulley J.L. Cancer vaccines: moving beyond current paradigms. Clin Cancer Res 13 July (13) (2007) 3776-3782
    • (2007) Clin Cancer Res , vol.13 , Issue.July 13 , pp. 3776-3782
    • Schlom, J.1    Arlen, P.M.2    Gulley, J.L.3
  • 11
    • 0344412934 scopus 로고    scopus 로고
    • Modified vaccinia virus Ankara recombinants are as potent as vaccinia recombinants in diversified prime and boost vaccine regimens to elicit therapeutic antitumor responses
    • Hodge J.W., Poole D.J., Aarts W.M., Gomez Yafal A., Gritz L., and Schlom J. Modified vaccinia virus Ankara recombinants are as potent as vaccinia recombinants in diversified prime and boost vaccine regimens to elicit therapeutic antitumor responses. Cancer Res 63 November (22) (2003) 7942-7949
    • (2003) Cancer Res , vol.63 , Issue.November 22 , pp. 7942-7949
    • Hodge, J.W.1    Poole, D.J.2    Aarts, W.M.3    Gomez Yafal, A.4    Gritz, L.5    Schlom, J.6
  • 12
    • 48549088424 scopus 로고    scopus 로고
    • Vaccination of prostate cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax), a phase 2 trial
    • Amato R.J., Drury N., Naylor S., Jac J., Saxena S., Cao A., et al. Vaccination of prostate cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax), a phase 2 trial. J Immunother 31 July-August (6) (2008) 577-585
    • (2008) J Immunother , vol.31 , Issue.July-August 6 , pp. 577-585
    • Amato, R.J.1    Drury, N.2    Naylor, S.3    Jac, J.4    Saxena, S.5    Cao, A.6
  • 13
    • 58149354757 scopus 로고    scopus 로고
    • Vaccination of renal cell cancer patients with modified vaccinia Ankara delivering tumor antigen 5T4 (TroVax) administered with interleukin 2: a phase II trial
    • Amato R.J., Shingler W., Naylor S., Jac J., Willis J., Saxena S., et al. Vaccination of renal cell cancer patients with modified vaccinia Ankara delivering tumor antigen 5T4 (TroVax) administered with interleukin 2: a phase II trial. Clin Cancer Res 14 November (22) (2008) 7504-7510
    • (2008) Clin Cancer Res , vol.14 , Issue.November 22 , pp. 7504-7510
    • Amato, R.J.1    Shingler, W.2    Naylor, S.3    Jac, J.4    Willis, J.5    Saxena, S.6
  • 14
    • 50349090322 scopus 로고    scopus 로고
    • A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV non-small cell lung cancer
    • Ramlau R., Quoix E., Rolski J., Pless M., Lena H., Levy E., et al. A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV non-small cell lung cancer. J Thorac Oncol 3 July (7) (2008) 735-744
    • (2008) J Thorac Oncol , vol.3 , Issue.July 7 , pp. 735-744
    • Ramlau, R.1    Quoix, E.2    Rolski, J.3    Pless, M.4    Lena, H.5    Levy, E.6
  • 16
    • 0034857126 scopus 로고    scopus 로고
    • Induction of simian immunodeficiency virus (SIV)-specific CTL in rhesus macaques by vaccination with modified vaccinia virus Ankara expressing SIV transgenes: influence of pre-existing anti-vector immunity
    • Sharpe S., Polyanskaya N., Dennis M., Sutter G., Hanke T., Erfle V., et al. Induction of simian immunodeficiency virus (SIV)-specific CTL in rhesus macaques by vaccination with modified vaccinia virus Ankara expressing SIV transgenes: influence of pre-existing anti-vector immunity. J Gen Virol 82 September (Pt 9) (2001) 2215-2223
    • (2001) J Gen Virol , vol.82 , Issue.September PART 9 , pp. 2215-2223
    • Sharpe, S.1    Polyanskaya, N.2    Dennis, M.3    Sutter, G.4    Hanke, T.5    Erfle, V.6
  • 17
    • 60349131089 scopus 로고    scopus 로고
    • Immunogenicity of recombinant modified vaccinia Ankara following a single or multi-dose vaccine regimen in rhesus monkeys
    • Grandpre L.E., Duke-Cohan J.S., Ewald B.A., Devoy C., Barouch D.H., Letvin N.L., et al. Immunogenicity of recombinant modified vaccinia Ankara following a single or multi-dose vaccine regimen in rhesus monkeys. Vaccine 27 March (10) (2009) 1549-1556
    • (2009) Vaccine , vol.27 , Issue.March 10 , pp. 1549-1556
    • Grandpre, L.E.1    Duke-Cohan, J.S.2    Ewald, B.A.3    Devoy, C.4    Barouch, D.H.5    Letvin, N.L.6
  • 18
    • 0030988548 scopus 로고    scopus 로고
    • Diversified prime and boost protocols using recombinant vaccinia virus and recombinant non-replicating avian pox virus to enhance T-cell immunity and antitumor responses
    • Hodge J.W., McLaughlin J.P., Kantor J.A., and Schlom J. Diversified prime and boost protocols using recombinant vaccinia virus and recombinant non-replicating avian pox virus to enhance T-cell immunity and antitumor responses. Vaccine 15 April-May (6-7) (1997) 759-768
    • (1997) Vaccine , vol.15 , Issue.April-May 6-7 , pp. 759-768
    • Hodge, J.W.1    McLaughlin, J.P.2    Kantor, J.A.3    Schlom, J.4
  • 19
    • 0034551730 scopus 로고    scopus 로고
    • Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses
    • Marshall J.L., Hoyer R.J., Toomey M.A., Faraguna K., Chang P., Richmond E., et al. Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses. J Clin Oncol 18 December (23) (2000) 3964-3973
    • (2000) J Clin Oncol , vol.18 , Issue.December 23 , pp. 3964-3973
    • Marshall, J.L.1    Hoyer, R.J.2    Toomey, M.A.3    Faraguna, K.4    Chang, P.5    Richmond, E.6
  • 20
    • 0030663697 scopus 로고    scopus 로고
    • Enhancing efficacy of recombinant anticancer vaccines with prime/boost regimens that use two different vectors
    • Irvine K.R., Chamberlain R.S., Shulman E.P., Surman D.R., Rosenberg S.A., and Restifo N.P. Enhancing efficacy of recombinant anticancer vaccines with prime/boost regimens that use two different vectors. J Natl Cancer Inst 89 November (21) (1997) 1595-1601
    • (1997) J Natl Cancer Inst , vol.89 , Issue.November 21 , pp. 1595-1601
    • Irvine, K.R.1    Chamberlain, R.S.2    Shulman, E.P.3    Surman, D.R.4    Rosenberg, S.A.5    Restifo, N.P.6
  • 21
    • 2942726162 scopus 로고    scopus 로고
    • Modified-vaccinia-virus-Ankara (MVA) priming and fowlpox-virus booster elicit a stronger CD8+ T-cell response in mice against an HIV-1 epitope than does a DNA/poxvirus prime-booster approach
    • Vazquez-Blomquist D., Quintana D., and Duarte C.A. Modified-vaccinia-virus-Ankara (MVA) priming and fowlpox-virus booster elicit a stronger CD8+ T-cell response in mice against an HIV-1 epitope than does a DNA/poxvirus prime-booster approach. Biotechnol Appl Biochem 39 June (Pt 3) (2004) 313-318
    • (2004) Biotechnol Appl Biochem , vol.39 , Issue.June PART 3 , pp. 313-318
    • Vazquez-Blomquist, D.1    Quintana, D.2    Duarte, C.A.3
  • 22
    • 42949155679 scopus 로고    scopus 로고
    • Dendritic cells are preferentially targeted among hematolymphocytes by modified vaccinia virus Ankara and play a key role in the induction of virus-specific T cell responses in vivo
    • Liu L., Chavan R., and Feinberg M.B. Dendritic cells are preferentially targeted among hematolymphocytes by modified vaccinia virus Ankara and play a key role in the induction of virus-specific T cell responses in vivo. BMC Immunol 9 (2008) 15
    • (2008) BMC Immunol , vol.9 , pp. 15
    • Liu, L.1    Chavan, R.2    Feinberg, M.B.3
  • 23
    • 35448974187 scopus 로고    scopus 로고
    • Cross-priming of cytotoxic T cells dictates antigen requisites for modified vaccinia virus Ankara vector vaccines
    • Gasteiger G., Kastenmuller W., Ljapoci R., Sutter G., and Drexler I. Cross-priming of cytotoxic T cells dictates antigen requisites for modified vaccinia virus Ankara vector vaccines. J Virol 81 November (21) (2007) 11925-11936
    • (2007) J Virol , vol.81 , Issue.November 21 , pp. 11925-11936
    • Gasteiger, G.1    Kastenmuller, W.2    Ljapoci, R.3    Sutter, G.4    Drexler, I.5
  • 24
    • 43049088102 scopus 로고    scopus 로고
    • Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection
    • Samuelsson C., Hausmann J., Lauterbach H., Schmidt M., Akira S., Wagner H., et al. Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection. J Clin Invest 118 May (5) (2008) 1776-1784
    • (2008) J Clin Invest , vol.118 , Issue.May 5 , pp. 1776-1784
    • Samuelsson, C.1    Hausmann, J.2    Lauterbach, H.3    Schmidt, M.4    Akira, S.5    Wagner, H.6
  • 25
    • 36048967665 scopus 로고    scopus 로고
    • Modified vaccinia virus Ankara induces Toll-like receptor-independent type I interferon responses
    • Waibler Z., Anzaghe M., Ludwig H., Akira S., Weiss S., Sutter G., et al. Modified vaccinia virus Ankara induces Toll-like receptor-independent type I interferon responses. J Virol 81 November (22) (2007) 12102-12110
    • (2007) J Virol , vol.81 , Issue.November 22 , pp. 12102-12110
    • Waibler, Z.1    Anzaghe, M.2    Ludwig, H.3    Akira, S.4    Weiss, S.5    Sutter, G.6
  • 26
    • 0034596362 scopus 로고    scopus 로고
    • Enhanced activation of T cells by dendritic cells engineered to hyperexpress a triad of costimulatory molecules
    • Hodge J.W., Rad A.N., Grosenbach D.W., Sabzevari H., Yafal A.G., Gritz L., et al. Enhanced activation of T cells by dendritic cells engineered to hyperexpress a triad of costimulatory molecules. J Natl Cancer Inst 92 August (15) (2000) 1228-1239
    • (2000) J Natl Cancer Inst , vol.92 , Issue.August 15 , pp. 1228-1239
    • Hodge, J.W.1    Rad, A.N.2    Grosenbach, D.W.3    Sabzevari, H.4    Yafal, A.G.5    Gritz, L.6
  • 27
    • 0035132541 scopus 로고    scopus 로고
    • Granulocyte/macrophage-colony stimulating factor produced by recombinant avian poxviruses enriches the regional lymph nodes with antigen-presenting cells and acts as an immunoadjuvant
    • Kass E., Panicali D.L., Mazzara G., Schlom J., and Greiner J.W. Granulocyte/macrophage-colony stimulating factor produced by recombinant avian poxviruses enriches the regional lymph nodes with antigen-presenting cells and acts as an immunoadjuvant. Cancer Res 61 January (1) (2001) 206-214
    • (2001) Cancer Res , vol.61 , Issue.January 1 , pp. 206-214
    • Kass, E.1    Panicali, D.L.2    Mazzara, G.3    Schlom, J.4    Greiner, J.W.5
  • 28
    • 24744441000 scopus 로고    scopus 로고
    • Vaccines with enhanced costimulation maintain high avidity memory CTL
    • Yang S., Hodge J.W., Grosenbach D.W., and Schlom J. Vaccines with enhanced costimulation maintain high avidity memory CTL. J Immunol 175 September (6) (2005) 3715-3723
    • (2005) J Immunol , vol.175 , Issue.September 6 , pp. 3715-3723
    • Yang, S.1    Hodge, J.W.2    Grosenbach, D.W.3    Schlom, J.4
  • 29
    • 0028124259 scopus 로고
    • Mice transgenic for the human carcinoembryonic antigen gene maintain its spatiotemporal expression pattern
    • Eades-Perner A.M., van der Putten H., Hirth A., Thompson J., Neumaier M., von Kleist S., et al. Mice transgenic for the human carcinoembryonic antigen gene maintain its spatiotemporal expression pattern. Cancer Res 54 August (15) (1994) 4169-4176
    • (1994) Cancer Res , vol.54 , Issue.August 15 , pp. 4169-4176
    • Eades-Perner, A.M.1    van der Putten, H.2    Hirth, A.3    Thompson, J.4    Neumaier, M.5    von Kleist, S.6
  • 30
    • 0025766226 scopus 로고
    • Transduction and expression of the human carcinoembryonic antigen gene in a murine colon carcinoma cell line
    • Robbins P.F., Kantor J.A., Salgaller M., Hand P.H., Fernsten P.D., and Schlom J. Transduction and expression of the human carcinoembryonic antigen gene in a murine colon carcinoma cell line. Cancer Res 51 July (14) (1991) 3657-3662
    • (1991) Cancer Res , vol.51 , Issue.July 14 , pp. 3657-3662
    • Robbins, P.F.1    Kantor, J.A.2    Salgaller, M.3    Hand, P.H.4    Fernsten, P.D.5    Schlom, J.6
  • 31
    • 0036732043 scopus 로고    scopus 로고
    • Identification of an interferon-gamma-inducible carcinoembryonic antigen (CEA) CD8 (+) T-cell epitope, which mediates tumor killing in CEA transgenic mice
    • Schmitz J., Reali E., Hodge J.W., Patel A., Davis G., Schlom J., et al. Identification of an interferon-gamma-inducible carcinoembryonic antigen (CEA) CD8 (+) T-cell epitope, which mediates tumor killing in CEA transgenic mice. Cancer Res 62 September (17) (2002) 5058-5064
    • (2002) Cancer Res , vol.62 , Issue.September 17 , pp. 5058-5064
    • Schmitz, J.1    Reali, E.2    Hodge, J.W.3    Patel, A.4    Davis, G.5    Schlom, J.6
  • 32
    • 0026586396 scopus 로고
    • RMA/S cells present endogenously synthesized cytosolic proteins to class I-restricted cytotoxic T lymphocytes
    • Esquivel F., Yewdell J., and Bennink J. RMA/S cells present endogenously synthesized cytosolic proteins to class I-restricted cytotoxic T lymphocytes. J Exp Med 175 January (1) (1992) 163-168
    • (1992) J Exp Med , vol.175 , Issue.January 1 , pp. 163-168
    • Esquivel, F.1    Yewdell, J.2    Bennink, J.3
  • 33
    • 62749084521 scopus 로고    scopus 로고
    • Modified vaccinia virus Ankara (MVA) triggers chemotaxis of monocytes and early respiratory immigration of leukocytes by induction of CCL2 expression
    • Lehmann M.H., Kastenmuller W., Kandemir J.D., Brandt F., Suezer Y., and Sutter G. Modified vaccinia virus Ankara (MVA) triggers chemotaxis of monocytes and early respiratory immigration of leukocytes by induction of CCL2 expression. J Virol 83 March (6) (2009) 2540-2552
    • (2009) J Virol , vol.83 , Issue.March 6 , pp. 2540-2552
    • Lehmann, M.H.1    Kastenmuller, W.2    Kandemir, J.D.3    Brandt, F.4    Suezer, Y.5    Sutter, G.6
  • 34
    • 4043142172 scopus 로고    scopus 로고
    • Modified vaccinia virus Ankara induces moderate activation of human dendritic cells
    • Drillien R., Spehner D., and Hanau D. Modified vaccinia virus Ankara induces moderate activation of human dendritic cells. J Gen Virol 85 August (Pt 8) (2004) 2167-2175
    • (2004) J Gen Virol , vol.85 , Issue.August PART 8 , pp. 2167-2175
    • Drillien, R.1    Spehner, D.2    Hanau, D.3
  • 35
    • 0033195223 scopus 로고    scopus 로고
    • Paramunity-inducing effects of vaccinia strain MVA
    • Vilsmeier B. Paramunity-inducing effects of vaccinia strain MVA. Berl Munch Tierarztl Wochenschr 112 September (9) (1999) 329-333
    • (1999) Berl Munch Tierarztl Wochenschr , vol.112 , Issue.September 9 , pp. 329-333
    • Vilsmeier, B.1
  • 36
    • 0029176287 scopus 로고
    • Novel vaccinia vector derived from the host range restricted and highly attenuated MVA strain of vaccinia virus
    • Sutter G., and Moss B. Novel vaccinia vector derived from the host range restricted and highly attenuated MVA strain of vaccinia virus. Dev Biol Stand 84 (1995) 195-200
    • (1995) Dev Biol Stand , vol.84 , pp. 195-200
    • Sutter, G.1    Moss, B.2
  • 38
    • 33846093410 scopus 로고    scopus 로고
    • Safety, immunogenicity and efficacy of modified vaccinia Ankara (MVA) against Dryvax challenge in vaccinia-naive and vaccinia-immune individuals
    • Parrino J., McCurdy L.H., Larkin B.D., Gordon I.J., Rucker S.E., Enama M.E., et al. Safety, immunogenicity and efficacy of modified vaccinia Ankara (MVA) against Dryvax challenge in vaccinia-naive and vaccinia-immune individuals. Vaccine 25 February (8) (2007) 1513-1525
    • (2007) Vaccine , vol.25 , Issue.February 8 , pp. 1513-1525
    • Parrino, J.1    McCurdy, L.H.2    Larkin, B.D.3    Gordon, I.J.4    Rucker, S.E.5    Enama, M.E.6
  • 39
    • 32844466244 scopus 로고    scopus 로고
    • Safety and immunogenicity of IMVAMUNE, a promising candidate as a third generation smallpox vaccine
    • Vollmar J., Arndtz N., Eckl K.M., Thomsen T., Petzold B., Mateo L., et al. Safety and immunogenicity of IMVAMUNE, a promising candidate as a third generation smallpox vaccine. Vaccine 24 March (12) (2006) 2065-2070
    • (2006) Vaccine , vol.24 , Issue.March 12 , pp. 2065-2070
    • Vollmar, J.1    Arndtz, N.2    Eckl, K.M.3    Thomsen, T.4    Petzold, B.5    Mateo, L.6
  • 40
    • 0032715788 scopus 로고    scopus 로고
    • Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion
    • Engelmayer J., Larsson M., Subklewe M., Chahroudi A., Cox W.I., Steinman R.M., et al. Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion. J Immunol 163 December (12) (1999) 6762-6768
    • (1999) J Immunol , vol.163 , Issue.December 12 , pp. 6762-6768
    • Engelmayer, J.1    Larsson, M.2    Subklewe, M.3    Chahroudi, A.4    Cox, W.I.5    Steinman, R.M.6
  • 41
    • 33748642155 scopus 로고    scopus 로고
    • Differences and similarities in viral life cycle progression and host cell physiology after infection of human dendritic cells with modified vaccinia virus Ankara and vaccinia virus
    • Chahroudi A., Garber D.A., Reeves P., Liu L., Kalman D., and Feinberg M.B. Differences and similarities in viral life cycle progression and host cell physiology after infection of human dendritic cells with modified vaccinia virus Ankara and vaccinia virus. J Virol 80 September (17) (2006) 8469-8481
    • (2006) J Virol , vol.80 , Issue.September 17 , pp. 8469-8481
    • Chahroudi, A.1    Garber, D.A.2    Reeves, P.3    Liu, L.4    Kalman, D.5    Feinberg, M.B.6
  • 42
    • 0031899907 scopus 로고    scopus 로고
    • Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine
    • Blanchard T.J., Alcami A., Andrea P., and Smith G.L. Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine. J Gen Virol 79 May (Pt 5) (1998) 1159-1167
    • (1998) J Gen Virol , vol.79 , Issue.May PART 5 , pp. 1159-1167
    • Blanchard, T.J.1    Alcami, A.2    Andrea, P.3    Smith, G.L.4
  • 43
    • 61749097912 scopus 로고    scopus 로고
    • Interferon-alpha differentially affects homeostasis of human plasmacytoid and myeloid dendritic cells
    • Cicinnati V.R., Kang J., Hou J., Lindemann M., Koop K., Tuting T., et al. Interferon-alpha differentially affects homeostasis of human plasmacytoid and myeloid dendritic cells. J Interferon Cytokine Res 29 March (3) (2009) 146-160
    • (2009) J Interferon Cytokine Res , vol.29 , Issue.March 3 , pp. 146-160
    • Cicinnati, V.R.1    Kang, J.2    Hou, J.3    Lindemann, M.4    Koop, K.5    Tuting, T.6
  • 44
    • 33846026736 scopus 로고    scopus 로고
    • Dendritic cells in transplantation and immune-based therapies
    • Young J.W., Merad M., and Hart D.N. Dendritic cells in transplantation and immune-based therapies. Biol Blood Marrow Transplant 13 January (1 Suppl. 1) (2007) 23-32
    • (2007) Biol Blood Marrow Transplant , vol.13 , Issue.January 1 SUPPL. 1 , pp. 23-32
    • Young, J.W.1    Merad, M.2    Hart, D.N.3
  • 45
    • 67651183588 scopus 로고    scopus 로고
    • MVA-MUC1-IL2 vaccine immunotherapy (TG4010) improves PSA doubling time in patients with prostate cancer with biochemical failure
    • (Epub ahead of print)
    • Dreicer R., Stadler W.M., Ahmann F.R., Whiteside T., Bizouarne N., Acres B., et al. MVA-MUC1-IL2 vaccine immunotherapy (TG4010) improves PSA doubling time in patients with prostate cancer with biochemical failure. Invest New Drugs October (2008) (Epub ahead of print)
    • (2008) Invest New Drugs , Issue.October
    • Dreicer, R.1    Stadler, W.M.2    Ahmann, F.R.3    Whiteside, T.4    Bizouarne, N.5    Acres, B.6
  • 46
    • 34547652648 scopus 로고    scopus 로고
    • Vaccination of colorectal cancer patients with modified vaccinia Ankara encoding the tumor antigen 5T4 (TroVax) given alongside chemotherapy induces potent immune responses
    • Harrop R., Drury N., Shingler W., Chikoti P., Redchenko I., Carroll M.W., et al. Vaccination of colorectal cancer patients with modified vaccinia Ankara encoding the tumor antigen 5T4 (TroVax) given alongside chemotherapy induces potent immune responses. Clin Cancer Res 13 August (15 Pt 1) (2007) 4487-4494
    • (2007) Clin Cancer Res , vol.13 , Issue.August 15 PART 1 , pp. 4487-4494
    • Harrop, R.1    Drury, N.2    Shingler, W.3    Chikoti, P.4    Redchenko, I.5    Carroll, M.W.6
  • 47
    • 67649302947 scopus 로고    scopus 로고
    • Oxford Biomedica Announces Data Safety Monitoring Board Recommendation for TROVAX Phase III TRIST Study; 2008. Available from:, cited February 2009
    • Oxford Biomedica Announces Data Safety Monitoring Board Recommendation for TROVAX Phase III TRIST Study; 2008. Available from: http://www.oxfordbiomedica.co.uk/news/2008-ob-21.asp [cited February 2009].
  • 48
    • 0037989845 scopus 로고    scopus 로고
    • Vaccine therapy of established tumors in the absence of autoimmunity
    • Hodge J.W., Grosenbach D.W., Aarts W.M., Poole D.J., and Schlom J. Vaccine therapy of established tumors in the absence of autoimmunity. Clin Cancer Res 9 May (5) (2003) 1837-1849
    • (2003) Clin Cancer Res , vol.9 , Issue.May 5 , pp. 1837-1849
    • Hodge, J.W.1    Grosenbach, D.W.2    Aarts, W.M.3    Poole, D.J.4    Schlom, J.5


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