Bone Modifiers and the Quest to Slow Progression of Aortic Stenosis

American Journal of Cardiology

Volumn 104, Issue 1, 2009, Pages 125-127

  Goldstein, Robert E ^a  

^a Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; VITAMIN D;

AORTA STENOSIS; AORTA VALVE CALCIFICATION; AORTA VALVE DISEASE; ARTERY CALCIFICATION; CONTROLLED STUDY; DISEASE CONTROL; DISEASE COURSE; DISEASE SEVERITY; DRUG MECHANISM; ECHOCARDIOGRAPHY; EDITORIAL; FOLLOW UP; HUMAN; NONHUMAN; OSTEOPOROSIS; PRIORITY JOURNAL; RETROSPECTIVE STUDY; VITAMIN SUPPLEMENTATION;

AGED; ANIMALS; AORTIC VALVE STENOSIS; BONE DENSITY CONSERVATION AGENTS; DIPHOSPHONATES; DISEASE PROGRESSION; HUMANS; MIDDLE AGED; OSTEOPOROSIS;

EID: 67649321427     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2009.02.054     Document Type: Editorial

References (13)

1. Roberts C.M. At 93, confronted with the decision of a lifetime; facing the end on his terms. The Washington Post (2004) A.01 August 29
2. Rosengart T.K., Feldman T., Borger M.A., Vassiliades Jr. T.A., Gillinov A.M., Hoercher K.J., Vahanian A., Bonow R.O., and O'Neill W. Percutaneous and minimally invasive valve procedures: a scientific statement from the American Heart Association. Circulation 117 (2008) 1750-1767
3. Messika-Zeitoun D., Bielak L.F., Peyser P.A., Sheedy P.F., Turner S.T., Nkomo V.T., Breen J.F., Maalouf J., Scott C., and Tajik A.J. Aortic valve calcification. Determinants and progression in the population. Arterioscler Thromb Vasc Biol 27 (2007) 642-648
4. Otto C.M. Calcific aortic stenosis-time to look more closely at the valve. N Engl J Med 359 (2008) 1395-1398
5. O'Brien K.D. Pathogenesis of calcific aortic valve disease. A disease process comes of age (and a good deal more). Arterioscler Thromb Vasc Biol 26 (2006) 1721-1728
6. Rossebø A.B., Pedersen T.R., Boman K., Brudi P., Chambers J.B., Egstrup K., Gerdts E., Gohlke-Bärwolf C., Holme I., Kesäniemi Y.A., Malbecq W., Nienaber C.A., Ray S., Skjaerpe T., Wachtell K., Willenheimer R., and SEAS Investigators. Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis. N Engl J Med 359 (2008) 1343-1356
7. Rosenhek R., Rader F., Loho N., Gabriel H., Heger M., Klaar U., Schemper M., Binder T., Maurer G., and Baumgartner H. Statins but not angiotensin-converting enzyme inhibitors delay progression of aortic stenosis. Circulation 110 (2004) 1291-1295
8. Skolnick A.H., Osranek M., Formica P., and Kronzon I. Osteoporosis treatment and progression of aortic stenosis. Am J Cardiol 103 (2009) 122-124
9. Tamura K., Suzuki Y., Matsushita M., Fujii H., Miyaura C., Aizawa S., and Kogo H. Prevention of aortic calcification by etidronate in the renal failure rat model. Eur J Pharmacol 558 (2007) 159-166
10. Drake M.T., Clarke B.L., and Khosla S. Bisphosphonates: mechanism of action and role in clinical practice. Mayo Clin Proc 83 (2008) 1032-1045
11. Mohler III E.R., Chawla M.K., Chang A.W., Vyahare N., Levy R.J., Graham L., and Gannon F.H. Identification and characterization of calcifying valve cells from human and canine aortic valves. J Heart Valve Dis 8 (1999) 254-260
12. Price P.A., Faus S.A., and Williamson M.K. Bisphosphonates alendronate and ibandronate inhibit artery calcification at doses comparable to those that inhibit bone resorption. Arterioscler Thromb Vasc Biol 21 (2001) 817-824
13. Demer L.L., and Tintut Y. Vascular calcification. Pathobiology of a multifaceted disease. Circulation 117 (2008) 2938-2948