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Volumn 17, Issue 3, 2009, Pages 255-263

Sensitivity of older patients to antipsychotic motor side effects: A PET study examining potential mechanisms

Author keywords

Aging; Antipsychotic; Dopamine; Extrapyramidal side effects; Schizophrenia

Indexed keywords

DOPAMINE 2 RECEPTOR; LORAZEPAM; METHADONE; PALIPERIDONE; PAROXETINE; RACLOPRIDE C 11; RISPERIDONE; SERTRALINE;

EID: 67649283706     PISSN: 10647481     EISSN: 15457214     Source Type: Journal    
DOI: 10.1097/JGP.0b013e318198776d     Document Type: Article
Times cited : (61)

References (40)
  • 1
    • 50349095100 scopus 로고    scopus 로고
    • Effects of age and age of onset on prescribed antipsychotic dose in schizophrenia spectrum disorders: A survey of 1,418 patients in Japan
    • Uchida H, Suzuki T, Mamo DC, et al: Effects of age and age of onset on prescribed antipsychotic dose in schizophrenia spectrum disorders: a survey of 1,418 patients in Japan. Am J Geriatr Psychiatry 2008; 16:584-593
    • (2008) Am J Geriatr Psychiatry , vol.16 , pp. 584-593
    • Uchida, H.1    Suzuki, T.2    Mamo, D.C.3
  • 2
    • 34548068081 scopus 로고    scopus 로고
    • Increased prevalence of falls among elderly individuals with mental health and substance abuse conditions
    • Finkelstein E, Prabhu M, Chen H: Increased prevalence of falls among elderly individuals with mental health and substance abuse conditions. Am J Geriatr Psychiatry 2007; 15:611-619
    • (2007) Am J Geriatr Psychiatry , vol.15 , pp. 611-619
    • Finkelstein, E.1    Prabhu, M.2    Chen, H.3
  • 3
    • 0001057795 scopus 로고
    • A survey of drug-induced extrapyramidal reactions
    • Ayd FJ Jr: A survey of drug-induced extrapyramidal reactions. JAMA 1961; 25:102-108
    • (1961) JAMA , vol.25 , pp. 102-108
    • Ayd Jr, F.J.1
  • 4
    • 26844538114 scopus 로고    scopus 로고
    • Risk of death with atypical antipsychotic drug treatment for dementia: Meta-analysis of randomized placebo-controlled trials
    • Schneider LS, Dagerman KS, Insel P: Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials. JAMA 2005; 294:1934-1943
    • (2005) JAMA , vol.294 , pp. 1934-1943
    • Schneider, L.S.1    Dagerman, K.S.2    Insel, P.3
  • 5
    • 38449111254 scopus 로고    scopus 로고
    • Antipsychotic medication dispensing and risk of death in veterans and war widows 65 years and older
    • Hollis J, Grayson D, Forrester L, et al: Antipsychotic medication dispensing and risk of death in veterans and war widows 65 years and older. Am J Geriatr Psychiatry 2007; 15:932-941
    • (2007) Am J Geriatr Psychiatry , vol.15 , pp. 932-941
    • Hollis, J.1    Grayson, D.2    Forrester, L.3
  • 8
    • 0034025771 scopus 로고    scopus 로고
    • Relationship between dopamine D(2) occupancy, clinical response, and side effects: A double-blind PET study of first-episode schizophrenia
    • Kapur S, Zipursky R, Jones C, et al: Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia. Am J Psychiatry 2000; 157:514-520
    • (2000) Am J Psychiatry , vol.157 , pp. 514-520
    • Kapur, S.1    Zipursky, R.2    Jones, C.3
  • 9
    • 36949008116 scopus 로고    scopus 로고
    • 2 receptor occupancy of olanzapine pamoate depot using positron emission tomography: An open-label study in patients with schizophrenia
    • 2 receptor occupancy of olanzapine pamoate depot using positron emission tomography: an open-label study in patients with schizophrenia. Neuropsychopharmacology 2008; 33:298-304
    • (2008) Neuropsychopharmacology , vol.33 , pp. 298-304
    • Mamo, D.1    Kapur, S.2    Keshavan, M.3
  • 10
    • 2442457725 scopus 로고    scopus 로고
    • 2 and serotonin 5-HT2 receptor occupancy in patients with schizophrenia treated with therapeutic doses of ziprasidone
    • 2 and serotonin 5-HT2 receptor occupancy in patients with schizophrenia treated with therapeutic doses of ziprasidone. Am J Psychiatry 2004; 161:818-825
    • (2004) Am J Psychiatry , vol.161 , pp. 818-825
    • Mamo, D.1    Kapur, S.2    Shammi, C.M.3
  • 11
    • 0024328253 scopus 로고
    • Changing patterns of neuroleptic dosage over a decade
    • Reardon GT, Rifkin A, Schwartz A, et al: Changing patterns of neuroleptic dosage over a decade. Am J Psychiatry 1989; 146:726-729
    • (1989) Am J Psychiatry , vol.146 , pp. 726-729
    • Reardon, G.T.1    Rifkin, A.2    Schwartz, A.3
  • 12
    • 0030889597 scopus 로고    scopus 로고
    • 2-like dopamine receptors: Theory, validation, and changes during normal aging
    • 2-like dopamine receptors: theory, validation, and changes during normal aging. J Cereb Blood Flow Metab 1997; 17:316-330
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 316-330
    • Wong, D.F.1    Young, D.2    Wilson, P.D.3
  • 14
    • 67649279451 scopus 로고    scopus 로고
    • Why do the elderly need lower doses of antipsychotics? - evidence and mechanisms
    • in press
    • Uchida H, Mamo DC, Mulsant BH, et al: Why do the elderly need lower doses of antipsychotics? - evidence and mechanisms. J Clin Psychiatry, in press
    • J Clin Psychiatry
    • Uchida, H.1    Mamo, D.C.2    Mulsant, B.H.3
  • 15
    • 34247626125 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of atypical antipsychotics : A critical review of the relationship between plasma concentrations and clinical response
    • Mauri MC, Volonteri LS, Colasanti A, et al: Clinical pharmacokinetics of atypical antipsychotics : a critical review of the relationship between plasma concentrations and clinical response. Clin Pharmacokinet 2007; 46:359-388
    • (2007) Clin Pharmacokinet , vol.46 , pp. 359-388
    • Mauri, M.C.1    Volonteri, L.S.2    Colasanti, A.3
  • 16
    • 33744936006 scopus 로고    scopus 로고
    • Effect of age on functional P-glycoprotein in the blood-brain barrier measured by use of (R)-[(11)C]verapamil and positron emission tomography
    • Toornvliet R, van Berckel BN, Luurtsema G, et al: Effect of age on functional P-glycoprotein in the blood-brain barrier measured by use of (R)-[(11)C]verapamil and positron emission tomography. Clin Pharmacol Ther 2006; 79:540-548
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 540-548
    • Toornvliet, R.1    van Berckel, B.N.2    Luurtsema, G.3
  • 17
    • 0004235298 scopus 로고
    • American Psychiatric Association:, 4th ed. Washington, DC, American Psychiatric Association
    • American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Washington, DC, American Psychiatric Association, 1994
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 19
    • 0023606101 scopus 로고
    • The positive and negative syndrome scale (PANSS) for schizophrenia
    • Kay SR, Fiszbein A, Opler LA: The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987; 13:261-276
    • (1987) Schizophr Bull , vol.13 , pp. 261-276
    • Kay, S.R.1    Fiszbein, A.2    Opler, L.A.3
  • 21
    • 0024358369 scopus 로고
    • A rating scale for drug-induced akathisia
    • Barnes TR: A rating scale for drug-induced akathisia. Br J Psychiatry 1989; 154:672-676
    • (1989) Br J Psychiatry , vol.154 , pp. 672-676
    • Barnes, T.R.1
  • 22
    • 67649245752 scopus 로고    scopus 로고
    • Guy W: ECDEU Assessment Manual for Psychopharmacology: Publication ADM 76-338. Washington, DC, US Department of Health, Education, and Welfare, 1976
    • Guy W: ECDEU Assessment Manual for Psychopharmacology: Publication ADM 76-338. Washington, DC, US Department of Health, Education, and Welfare, 1976
  • 23
    • 0030468875 scopus 로고    scopus 로고
    • Simplified reference tissue model for PET receptor studies
    • Lammertsma AA, Hume SP: Simplified reference tissue model for PET receptor studies. NeuroImage 1996; 4:153-158
    • (1996) NeuroImage , vol.4 , pp. 153-158
    • Lammertsma, A.A.1    Hume, S.P.2
  • 24
    • 34547846251 scopus 로고    scopus 로고
    • Consensus nomenclature for in vivo imaging of reversibly binding radioligands
    • Innis RB, Cunningham VJ, Delforge J, et al: Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J Cereb Blood Flow Metab 2007; 27:1533-1539
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 1533-1539
    • Innis, R.B.1    Cunningham, V.J.2    Delforge, J.3
  • 27
    • 0026718710 scopus 로고
    • 2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects
    • 2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects. Arch Gen Psychiatry 1992; 49:538-544
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 538-544
    • Farde, L.1    Nordstrom, A.L.2    Wiesel, F.A.3
  • 28
    • 0032982714 scopus 로고    scopus 로고
    • 2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia
    • 2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia. Am J Psychiatry 1999; 156:286-293
    • (1999) Am J Psychiatry , vol.156 , pp. 286-293
    • Kapur, S.1    Zipursky, R.B.2    Remington, G.3
  • 29
    • 0037205138 scopus 로고    scopus 로고
    • In vitro P-glycoprotein affinity for atypical and conventional antipsychotics
    • Boulton DW, DeVane CL, Liston HL, et al: In vitro P-glycoprotein affinity for atypical and conventional antipsychotics. Life Sci 2002; 71:163-169
    • (2002) Life Sci , vol.71 , pp. 163-169
    • Boulton, D.W.1    DeVane, C.L.2    Liston, H.L.3
  • 30
    • 0018847716 scopus 로고
    • Neuroleptic/dopamine receptors: Elevation and reversal
    • List S, Seeman P: Neuroleptic/dopamine receptors: elevation and reversal. Adv Biochem Psychopharmacol 1980; 24:95-101
    • (1980) Adv Biochem Psychopharmacol , vol.24 , pp. 95-101
    • List, S.1    Seeman, P.2
  • 31
    • 0023556233 scopus 로고
    • Human brain dopamine receptors in children and aging adults
    • Seeman P, Bzowej NH, Guan HC, et al: Human brain dopamine receptors in children and aging adults. Synapse 1987; 1:399-404
    • (1987) Synapse , vol.1 , pp. 399-404
    • Seeman, P.1    Bzowej, N.H.2    Guan, H.C.3
  • 32
    • 84903173461 scopus 로고    scopus 로고
    • Effect of nortriptyline and paroxetine on extrapyramidal signs and symptoms: A prospective double-blind study in depressed elderly patients
    • Mamo DC, Sweet RA, Mulsant BH, et al: Effect of nortriptyline and paroxetine on extrapyramidal signs and symptoms: a prospective double-blind study in depressed elderly patients. Am J Geriatr Psychiatry 2000; 8:226-231
    • (2000) Am J Geriatr Psychiatry , vol.8 , pp. 226-231
    • Mamo, D.C.1    Sweet, R.A.2    Mulsant, B.H.3
  • 33
    • 0018171707 scopus 로고
    • Neuroleptic-induced supersensitivity psychosis
    • Chouinard G, Jones BD, Annable L: Neuroleptic-induced supersensitivity psychosis. Am J Psychiatry 1978; 135:1409-1410
    • (1978) Am J Psychiatry , vol.135 , pp. 1409-1410
    • Chouinard, G.1    Jones, B.D.2    Annable, L.3
  • 34
    • 55949099579 scopus 로고    scopus 로고
    • Longitudinal MRI study in schizophrenia patients and their healthy siblings
    • Brans RG, van Haren NE, van Baal GC, et al: Longitudinal MRI study in schizophrenia patients and their healthy siblings. Br J Psychiatry 2008; 193:422-423
    • (2008) Br J Psychiatry , vol.193 , pp. 422-423
    • Brans, R.G.1    van Haren, N.E.2    van Baal, G.C.3
  • 35
    • 0023526285 scopus 로고
    • 2 dopamine receptors in schizophrenia, Alzheimer's, Parkinson's, and Huntington's diseases
    • 2 dopamine receptors in schizophrenia, Alzheimer's, Parkinson's, and Huntington's diseases. Neuropsychopharmacology 1987; 1:5-15
    • (1987) Neuropsychopharmacology , vol.1 , pp. 5-15
    • Seeman, P.1    Bzowej, N.H.2    Guan, H.C.3
  • 36
    • 0033626576 scopus 로고    scopus 로고
    • 2 receptor binding after long-term treatment with antipsychotics in humans: A clinical PET study
    • 2 receptor binding after long-term treatment with antipsychotics in humans: a clinical PET study. Psychopharmacology (Berl) 2000; 152:174-180
    • (2000) Psychopharmacology (Berl) , vol.152 , pp. 174-180
    • Silvestri, S.1    Seeman, M.V.2    Negrete, J.C.3
  • 37
    • 0026611591 scopus 로고
    • 2 receptor modulation in rat striatum and nucleus accumbens after subchronic and chronic haloperidol treatment
    • 2 receptor modulation in rat striatum and nucleus accumbens after subchronic and chronic haloperidol treatment. Brain Res 1992; 575:47-56
    • (1992) Brain Res , vol.575 , pp. 47-56
    • Laruelle, M.1    Jaskiw, G.E.2    Lipska, B.K.3
  • 38
    • 0031595586 scopus 로고    scopus 로고
    • 2 receptor occupancy of olanzapine in schizophrenia: A PET investigation
    • 2 receptor occupancy of olanzapine in schizophrenia: a PET investigation. Am J Psychiatry 1998; 155:921-928
    • (1998) Am J Psychiatry , vol.155 , pp. 921-928
    • Kapur, S.1    Zipursky, R.B.2    Remington, G.3
  • 39
    • 0025287084 scopus 로고
    • Correction of PET data for partial volume effects in human cerebral cortex by MR imaging
    • Meltzer CC, Leal JP, Mayberg HS, et al: Correction of PET data for partial volume effects in human cerebral cortex by MR imaging. J Comput Assist Tomogr 1990; 14:561-570
    • (1990) J Comput Assist Tomogr , vol.14 , pp. 561-570
    • Meltzer, C.C.1    Leal, J.P.2    Mayberg, H.S.3
  • 40
    • 34248571925 scopus 로고    scopus 로고
    • Assessment of 11C-PE2I binding to the neuronal dopamine transporter in humans with the high-spatial-resolution PET scanner HRRT
    • Leroy C, Comtat C, Trebossen R, et al: Assessment of 11C-PE2I binding to the neuronal dopamine transporter in humans with the high-spatial-resolution PET scanner HRRT. J Nucl Med 2007; 48:538-546
    • (2007) J Nucl Med , vol.48 , pp. 538-546
    • Leroy, C.1    Comtat, C.2    Trebossen, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.