Neurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern Bobwhite (Colinus virginianus)

Toxicological Sciences

Volumn 110, Issue 1, 2009, Pages 168-180

  Gust, Kurt A ^a   Pirooznia, Mehdi ^b   Quinn, Michael J ^c   Johnson, Mark S ^c   Escalon, Lynn ^d   Indest, Karl J ^a   Guan, Xin ^d   Clarke, Joan ^a   Deng, Youping ^d   Gong, Ping ^d   Perkins, Edward J ^a  

^a U S ARMY ENGINEER RESEARCH AND DEVELOPMENT CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c US Army Center for Health Promotion and Preventive Medicine   (United States)

^d US ARMY ENGINEER RESEARCH AND DEVELOPMENT CENTER   (United States)

Author keywords

Genomics; Mechanisms of action; Munitions constituents; Seizures

Indexed keywords

CHLORPHENOTANE; COMPLEMENTARY DNA; CYCLONITE; TRINITROTOLUENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLINUS; COLINUS VIRGINIANUS; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; GENE EXPRESSION PROFILING; HYBRIDIZATION; LETHARGY; MALE; MOLECULAR MECHANICS; NERVE EXCITABILITY; NEUROTOXICOLOGY; NONHUMAN; REPOLARIZATION; SEIZURE; SIGNAL TRANSDUCTION; TOXICOGENETICS; WEIGHT REDUCTION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLINUS; COMPUTATIONAL BIOLOGY; DDT; DINITROBENZENES; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPLOSIVE AGENTS; FEMALE; GENE EXPRESSION PROFILING; IN SITU HYBRIDIZATION; INSECTICIDES; MALE; NEUROTOXINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TOXICOGENETICS; TRIAZINES;

AVES; COLINUS VIRGINIANUS;

EID: 67649211289     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp091     Document Type: Article

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