Influence of oral 2,4-dinitrotoluene exposure to the Northern Bobwhite (Colinus virginianus)

International Journal of Toxicology

Volumn 24, Issue 4, 2005, Pages 265-274

  Johnson, Mark S ^a   Michie, Mark W ^a   Bazar, Matthew A ^a   Gogal Jr , Robert M ^b  

^a U S ARMY CENTER FOR HEALTH PROMOTION AND PREVENTIVE MEDICINE   (United States)

^b VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

Author keywords

Birds; Bobwhite; DNT; Explosives; Gavage

Indexed keywords

2,4 DINITROTOLUENE; CORN OIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIRD; BODY WEIGHT; BRAIN; COLINUS; COLINUS VIRGINIANUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIARRHEA; DRUG DOSE REGIMEN; EVALUATION; FEMALE; HABITAT STRUCTURE; HISTOPATHOLOGY; ISOMERIZATION; KIDNEY; LD 50; LETHARGY; MALE; MILITARY PHENOMENA; MORBIDITY; NONHUMAN; NORTHERN BOBWHITE; OOCYTE DEVELOPMENT; OVARY; RISK ASSESSMENT; SOIL POLLUTION; WEIGHT REDUCTION;

ADMINISTRATION, ORAL; ANIMALS; BODY WEIGHT; CARCINOGENS; COLINUS; DINITROBENZENES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; FEMALE; KIDNEY; LETHAL DOSE 50; LIVER; MALE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; OVARY; REPRODUCTION; RISK ASSESSMENT; SOIL POLLUTANTS; TRIGLYCERIDES;

AVES; COLINUS VIRGINIANUS; ZEA MAYS;

EID: 23744512406     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1080/10915810591007247     Document Type: Article

References (27)

1. ASTM. 2002. Standard test method for estimating acute oral toxicity in rats. E 1163-98. Conshohocken, PA: American Society for Testing and Materials.
2. ATSDR. 1998. Toxicological profile for 2,4- and 2,6-dinitrotoluene. Atlanta, GA: Agency for Toxic Substances and Disease Registry, Public Health Service, U.S. Department of Health and Human Services.
3. Best, T. L., T. E. Garrison, and C. G. Schmitt. 1992. Ingestion of lead pellets by scaled quail (Callipepla squamata) and northern bobwhite (Colinus virginianus) in southeastern New Maxico. Texas Journal of Science 44(1):99-107.
4. Bloch, E., B. Gondos, M. Gatz, S. K. Varma, and B. Thysen. 1988. Reproductive toxicity of 2,4-dinitrotoluene in the rat. Toxicol. Appl. Pharmacol. 94:466-472.
5. 14C] toluene by freshly isolated Fischer-344 rat primary hepatocytes. Drug Metab. Dispos. 9:10-14.
6. Brennan, L. A. 1999. Northern Bobwhite (Colinus virginianus). In The birds of North America, No. 397, ed. A. Poole and F. Gill. Philadelphia, PA: The Birds of North America.
7. Brower, M. E., W. C. Roberts, W. R. Hartley, and C. Abernathy. 1994. 2,4- and 2,6-dinitrotoluene (DNT). In Drinking Water Health Advisory: Munitions II, United States Environmental Protection Agency Office of Drinking Water Advisories, ed. W. R. Hartley, W. C. Roberts, and B. J. Commons, 39-153. Ann Arbor, MI: Professional Administrative Services.
8. Dominguez, S. E., J. L. Menkel, A. Fairbrother, B. A. Williams, and R. W. Tanner. 1993. The effect of 2,4-dinitrophenol on the metabolic rate of bobwhite quail. Toxicol. Appl. Pharmacol. 123:226-233.
9. Ellis, H. V., III, J. R. Hodgson, S. W. Hwang, L. M. Halpap, D. O. Helton, B. S. Anderson, D. L. VanGoethem and C.-C. Lee. 1978. Mammalian toxicity of munitions compounds phase I: Acute oral toxicity, primary skin and eye irritation, dermal sensitization, disposition and metabolism, and Ames tests of additional compounds. ADA069333. Kansas City, MO: Midwest Research Institute. Supported by U.S. Army Medical Research and Development Command, Fort Detrick, Frederick, MD.
10. Ellis, H. V., III, C. B. Hong, C. C. Lee, J. C. Dacre, and J. P. Glennon. 1985. Subchronic and chronic toxicity studies of 2,4-dinitrotoluene. Part I. Beagle dogs. J. Am. Coll. Toxicol. 4:233-241.
11. Gionfriddo, J. P., and L. B. Best. 1996. Grit-use patterns in North American birds: The influence of diet, body size, and gender. Wilson Bull. 108:685-696.
12. Gogal, R. M., Jr., C. T. Larsen, M. R. Prater, R. B. Duncan, D. L. Ward, M. S. Johnson, and S. D. Holladay. 2002. Influence of dietary exposure to TNT derivatives on the immune system of the northern bobwhite quail (Colinus virginianus). Environ. Toxicol. Chem. 21:81-86.
13. Hong, C. B., H. V. Ellis III, C. C. Lee, H. Sprinz, J. C. Dacre, and J. P. Glennon. 1985. Subchronic and chronic toxicity studies of 2,4-dinitrotoluene. Part III. CD-1 mice. J. Am. Coll. Toxicol 4:257-269.
14. Jenkins, T. F., J. C. Pennington, T. A. Ranney, T. E. Berry, Jr, P. H. Miyares, M. E. Walsh, A. D. Hewitt, N. M. Perron, L. V. Parker, C. A. Hayes. and E. G. Wahlgren. 2001. Characterization of explosives contamination at military firing ranges. ERDC TR-01-5. Final/Technical Report. Hanover, NH: Engineer Research and Development Center, U.S. Army Corps of Engineers.
15. Johnson, M. S., M. W. Michie, M. A. Bazar, R. M. Gogal, Jr., and C. J. Salice. 2005. Responses of oral 2,4,6-trinitrotoluene (TNT) exposure to the common pigeon (Columba livia): A phylogenic and methodological comparison. Int. J. Toxicol. 24(4):219-227.
16. Lane, R. W., G. S. Simon, R. W. Dougherty, J. L. Egle Jr., and J. F. Borzelleca. 1985. Reproductive toxicity and lack of dominant lethal effects of 2,4-dinitrotoluene in the male rat. Drug Chem. Toxicol. 8:265-280.
17. Lee, C. C., J. V. Dilley, J. R. Hodgson, D. O. Helton, and W. J. Wiegand. 1975. Mammalian toxicity of munitions compounds phase I: acute oral toxicity, primary skin and eye irritation, dermal sensitization, and disposition and metabolism. Midwest Research Institute, Kansas City, MO. Prepared for Environmental Protection Research Division, U.S. Army Medical Research and Development Command, Washington, DC.
18. Lee, C. C., H. V. Ellis III, J. J. Kowalski, J. R. Hodgson, S. W. Hwang, R. D. Short, J. C. Bhandari, J. L. Sanyer, T. W. Reddig, and J. L. Minor. 1978. Mammalian toxicity of munitions compounds. Part II: Effects of multiple doses of 2,4-dinitrotoluene. ADA061715. Kansas City, MO: Midwest Research Institute. Supported by U.S. Army Medical Research and Development Command, Fort Detrick, Frederick, MD.
19. Lee, C. C., C. B. Hong, H. V. Ellis III, J. C. Dacre, and J. P. Glennon. 1985. Subchronic and chronic toxicity studies of 2,4-dinitrotoluene. Part II. CD rats. J. Am. Coll. Toxicol. 4:243-256.
20. McCann, L. J. 1961. Grit as an ecological factor. Am. Midl. Nat. 65:187-192.
21. Medinsky, M. A., and J. G. Dent. 1983. Biliary excretion and enterohepatic circulation of 2,4-dinitrotoluene metabolites in Fischer-344 rats. Toxicol. Appl. Pharmacol. 68:359-366.
22. OECD. 2001. Guideline for Testing of Chemicals-Acute Oral Toxicity-Up/Down Procedure. 425. Paris, France: Organisation for Economic Cooperation and Development.
23. Ritchie, B. W., G. J., Harrison, and L. R. Harrison. 1994. Avion medicine: Principles and application. Lake Worth, FL: Wingers Publishing.
24. Shivaprasad, H. L. 1998. An overview of anatomy, physiology, and pathology of urinary system in birds. In Association of Avion Veterinarians Proceedings, 201-205.
25. USEPA. 2002. Health Effects Test Guidelines OPPTS 870.1100. Acute Oral Toxicity. EPA 712-C-02-190. Washington DC: Office of Prevention. Pesticides, and Toxic Substances, United States Environmental Protection Agency.
26. Walsh, M. E., and T. F. Jenkins. 1992. Identification of TNT Transformation Products in Soil. 92-16. Special Report. Hanover, NH: U.S. Army Corps of Engineers, Cold Regions Research & Engineering Laboratory.
27. Wink, M., A. Hofer, M. Bilfinger, E. Englert, M. Martin, and D. Schneider. 1993. Geese and dietary alleochemicals: Food palatability and geophagy. Chemoecology 4:93-107.