Subacute toxicity of oral 2,6-dinitrotoluene and 1,3,5-trinitro-1,3,5-triazine (RDX) exposure to the northern bobwhite (Colinus virginianus)

Environmental Toxicology and Chemistry

Volumn 26, Issue 7, 2007, Pages 1481-1487

  Johnson, Mark S ^a   Quinn, Michael J ^a   Bazar, Matthew A ^a   Gust, Kurt A ^b   Escalon, B Lynn ^b   Perkins, Edward J ^c  

^a U S ARMY CENTER FOR HEALTH PROMOTION AND PREVENTIVE MEDICINE   (United States)

^b SpecPro   (United States)

^c US ARMY ENGINEER RESEARCH AND DEVELOPMENT CENTER   (United States)

Author keywords

Birds; Bobwhite; Dinitrotoluene; Energetics; Explosives

Indexed keywords

BOBWHITE; DINITROTOLUENE; ENERGETICS; RDX;

BIRDS; BRAIN; DEHYDRATION; EXPLOSIVES; SOILS;

TOLUENE;

2,6 DINITROTOLUENE; CORN OIL; CYCLONITE;

AROMATIC HYDROCARBON; BODY MASS; BRAIN; CONCENTRATION (COMPOSITION); ENERGETICS; EXPLOSIVE; GAMEBIRD; NERVOUS SYSTEM; POLLUTION EFFECT; POLLUTION EXPOSURE; TOXICITY;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIRD; BODY MASS; BRAIN; CLONIC SEIZURE; COLINUS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEATH; DEHYDRATION; EXPOSURE; FEEDING; FEMALE; FOOD INTAKE; GASTROINTESTINAL SYMPTOM; MALE; NONHUMAN; PRIORITY JOURNAL; TONIC SEIZURE; WEIGHT REDUCTION;

ADMINISTRATION, ORAL; ANIMALS; CHROMATOGRAPHY, GAS; COLINUS; DINITROBENZENES; RISK ASSESSMENT; TRIAZINES;

AVES; COLINUS VIRGINIANUS; ZEA MAYS;

EID: 34447542587     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/06-525.1     Document Type: Article

References (22)

1. U.S. General Accounting Office (GAO). 2004. DoD Operational Ranges: More reliable cleanup cost estimates and a proactive approach to identifying contamination are needed. GAO-04-601. Washington, DC.
2. Agency for Toxic Substances Disease Registry (ATSDR). 1998. Toxicological profile for 2,4- and 2,6-dinitrotoluene. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA.
3. Brower ME, Roberts WC, Hartley WR, Abernathy C. 1994. 2,4-and 2,6-dinitrotoluene (DNT). In Hartley WR, Roberts WC, Commons BJ, eds, Drinking Water Health Advisory: Munitions II, United States Environmental Protection Agency Office of Drinking Water Advisories. Professional Administrative Services, Ann Arbor, MI, USA, pp 39-153.
4. Pennington JC, Jenkins TF, Ampleman G, Thiboutot S, Brannon J, Clausen J, Hewitt AD, Brochu S, Dube R Lewis J, Ranney T, Faucher D, Gagnon A, Stark JA, Brousseau R Price CB, Lambert D, Marois A, Bouchard M, Walsh ME, Yost SL, Perron NM, Martel R, Jean S, Taylor S, Hayes CA, Ballard J-M, Walsh MR, Mirecki JE, Downe S, Collins NH, Porter B, Kara R. 2004. Distribution and fate of energetics on DoD test and training ranges. ERDC TR-04-4. U.S. Army Corps of Engineers, Engineer Research and Development Center, Vicksburg, MS.
5. Jenkins TF, Pennington JC, Ranney TA, Berry TE Jr, Miyares PH, Walsh ME, Hewitt AD, Perron NM, Parker LV, Hayes CA, Wahlgren EG. 2001. Characterization of explosives contamination at military firing ranges. ERDC TR-01-5. Final/Technical Report. Engineer Research and Development Center, U.S. Army Corps of Engineers, Hanover, NH.
6. Walsh ME, Jenkins TF. 1992. Identification of TNT transformation products in soil. 92-16. Special Report. U.S. Army Corps of Engineers, Cold Regions Research and Engineering Laboratory. Hanover, NH.
7. McCann LJ. 1961. Grit as an ecological factor. Am Midl Nat 65:187-192.
8. Wink M, Hofer A, Bilfinger M, Englert E, Martin M, Schneider D. 1993. Geese and dietary alleochemicals: Food palatability and geophagy. Chemoecology 4:93-107.
9. Gionfriddo JP, Best LB. 1996. Grit-use patterns in North American birds: The influence of diet, body size, and gender. Wilson Bull 108:685-696.
10. Best LB, Gionfriddo JP. 1994. Effects of surface texture and shape on grit selection by house sparrows and northern bobwhite. Wilson Bull 106:689-695.
11. Brennan LA. 1999. Northern bobwhite (Colinus virginianus). In Poole A, Gill F, eds, The Birds of North America, No. 397. The Birds of North America, Philadelphia, PA, USA, pp 1-28.
12. Gogal RM Jr, Johnson MS, Larsen CT, Prater MR, Duncan RB, Ward DL, Lee RB, Salice CJ, Jortner B, Holladay SD. 2003. Dietary oral exposure to 1,3,5-trinitro-1,3,5-triazine in the northern bobwhite quail (Colinus virginianus). Environ Toxicol Chem 22:381-387.
13. Feder PI, Hobson DS, Olson CT, Joiner RL, Matthews MC. 1991. Stagewise, adaptive dose allocation for quantal response dose-response studies. Neurosci Biobehav Rev 15:109-114.
14. Feder PI, Olson CT, Hobson DS, Matthews MC, Joiner RL. 1991. Stagewise, group sequential experimental designs for quantal responses. One-sample and two-sample comparisons. Neurosci Biobehav Rev 15:129-133.
15. Johnson MS, Michie MW, Bazar MA, Gogal RM Jr. 2005. Influence of oral 2,4-dinitrotoluene exposure to the northern bobwhite (Colinus virginianus). Int J Toxicol 24:265-274.
16. Gogal RM Jr, Johnson MS, Larsen CT, Prater MR, Duncan RB, Ward DL, Holladay SD. 2002. Influence of dietary 2,4,6-trinitrotoluene exposure in the northern bobwhite (Colinus virginianus). Environ Toxicol Chem 21:81-86.
17. U.S. Environmental Protection Agency. 1994. Nitroaromatics and nitroamines by HPLC. Method 8330. Test Method for Evaluating Solid Waste Physical/Chemical Methods. SW-846, 3rd ed, Update II. Washington, DC.
18. U.S. Environmental Protection Agency. 2000. Explosives by gas chromatography. Method 8095. Test Method for Evaluating Solid Waste Physical/Chemical Methods. SW-846, Draft Update IVB. Washington, DC.
19. Cholakis JM, Wong LCK, Van Goethem DL, Minor J, Short R, Sprinz H, Ellis HV III. 1980. Mammalian toxicological evaluation of RDX. AD A092531. U.S. Army Medical Research and Development Command, Frederick, MD.
20. Levine BS, Furedi EM, Gordon DE, Burns JM, Lish PM. 1981. Thirteen-week toxicity study of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) in Fischer 344 rats. Toxicol Lett 8:241-245.
21. Burdette LJ, Cook LL, Dyer RS. 1988. Convulsant properties of cyclotrimethylenetrinitramine (RDX): Spontaneous, audiogenic, and amygdaloid kindled seizure activity. Toxicol Appl Pharmacol 92:436-444.
22. Ritchie BW, Harrison GJ, Harrison LR. 1994. Avian Medicine: Principles and Application. Wingers Publishing, Lake Worth, FL, USA.