Chemotherapeutic drug transport to brain tumor

Journal of Controlled Release

Volumn 137, Issue 3, 2009, Pages 203-210

  Arifin, Davis Yohanes ^a,b   Lee, Kam Yiu Timothy ^c   Wang, Chi Hwa ^a,b  

^a SINGAPORE MIT ALLIANCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c GLENEAGLES HOSPITAL   (Singapore)

Author keywords

Chemotherapy; Computational fluid dynamics; Convection; Diffusion; Simulation

Indexed keywords

5-FLUOROURACIL (5-FU); ANTIANGIOGENIC; BRAIN TUMORS; CARMUSTINE; CAVITY SURFACES; CHEMOTHERAPEUTIC AGENTS; CHEMOTHERAPEUTIC DRUGS; COMPUTATIONAL FLUID DYNAMICS SIMULATIONS; CONVECTION; DARCY'S LAW; DRUG CONCENTRATION; DRUG TRANSPORT; EFFECTIVE CONCENTRATION; INTERSTITIAL FLUIDS; MAGNETIC RESONANCE IMAGES; ORDERS OF MAGNITUDE; PACLITAXEL; PHYSICOCHEMICAL PROPERTY; RENORMALIZATION; SIMULATION; THREE-DIMENSIONAL (3D); TISSUE GEOMETRY;

CHEMOTHERAPY; COMPUTATIONAL FLUID DYNAMICS; FLUID DYNAMICS; FLUIDS; IMAGE PROCESSING; MAGNETIC RESONANCE IMAGING; THREE DIMENSIONAL; TUMORS;

TRANSPORT PROPERTIES;

CARMUSTINE; FLUOROURACIL; METHOTREXATE; PACLITAXEL; POLYMER;

ARTICLE; BRAIN TUMOR; BRAIN VENTRICLE; COMPUTATIONAL FLUID DYNAMICS; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; DRUG TRANSPORT; IMAGE ANALYSIS; INTERSTITIAL FLUID; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SIMULATION; THERMODYNAMICS; THREE DIMENSIONAL IMAGING;

ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; BRAIN; BRAIN NEOPLASMS; CARMUSTINE; COMPUTER SIMULATION; EXTRACELLULAR FLUID; FLUOROURACIL; HUMANS; MAGNETIC RESONANCE IMAGING; MODELS, BIOLOGICAL; PACLITAXEL;

EID: 67649114161     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.04.013     Document Type: Article

References (36)

1. Brem H., and Gabikian P. Biodegradable polymer implants to treat brain tumors. Journal of Controlled Release 74 (2001) 63-67
2. Fleming A.B., and Saltzman W.M. Pharmacokinetics of the carmustine implant. Clinical Pharmacokinetics 41 (2002) 403-419
3. Jain R.K., Tong R.T., and Munn L.L. Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model. Cancer Research 67 (2007) 2729-2735
4. Saltzman W.M., and Radomsky M.L. Drugs released from polymers: diffusion and elimination in brain tissue. Chemical Engineering Science 46 (1991) 2429-2444
5. Fung L.K., Shin M., Tyler B., Brem H., and Saltzman W.M. Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-1-nitrosurea in the rat brain. Pharmaceutical Research 13 (1996) 671-682
6. Fung L.K., Ewend M.G., Silis A., Sipos E.P., Thompson R., Watts M., Colvin O.M., Brem H., and Saltzman W.M. Pharmacokinetics of interstitial delivery of carmustine, 4-hydroperoxycyclophospamide, and paclitaxel from a biodegradable polymer implant in the monkey brain. Cancer Research 58 (1998) 672-684
7. Wang C.H., Li J., Teo C.S., and Lee T. The delivery of BCNU to brain tumors. Journal of Controlled Release 61 (1999) 21-41
8. Tan W.H.K., Wang F., Lee T., and Wang C.H. Computer simulation of the delivery of etanidazole to brain tumor from PLGA wafers: comparison between linear and double burst release systems. Biotechnology and Bioengineering 82 (2003) 278-288
9. Kalyanasundaram S., Calhoun V.D., and Leong K.W. A finite element model for predicting the distribution of drugs delivered intracranially to the brain. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 42 (1997) R1810-R1821
10. Weinberg B.D., Patel R.B., Exner A.A., Saidel G.M., and Gao J. Modeling doxorubicin transport to improve intratumoral drug delivery to RF ablated tumors. Journal of Controlled Release 124 (2007) 11-19
11. Shim E.B., Kwon Y.G., and Ko H.J. Computational analysis of tumor angiogenesis patterns using a two-dimensional model. Yonsei Medical Journal 46 (2005) 275-283
12. Kimelberg H.K. Water homeostasis in the brain: basic concepts. Neuroscience 120 (2004) 852-860
13. Rapoport S.I. A mathematical model for vasogenic brain edema. Journal of Theoretical Biology 74 (1978) 439-467
14. Gross J.F., and Popel A.S. Mathematical models of transport phenomena in normal and neoplastic tissue. In: Peterson H.I. (Ed). Tumor Blood Circulation (1979), CRC Press, Baca Raton 169-183
15. Baxter L.T., and Jain R.K. Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection. Microvascular Research 37 (1989) 77-104
16. Perry R.H. Perry's Chemical Engineers' Handbook (1997), McGraw-Hill, New York 59-71
17. Netti P.A., Travascio F., and Jain R.K. Coupled macromolecular transport and gel mechanics: poroviscoelastic approach. AIChE Journal 49 (2003) 1580-1596
18. Jain R.K. Transport of molecules in the tumor interstitium: a review. Cancer Research 47 (1987) 3039-3051
19. Boucher Y., Brekken C., Netti P.A., Baxter L.T., and Jain R.K. Intratumoral infusion of fluid: estimation of hydraulic conductivity and implications for the delivery of therapeutic agents. British Journal of Cancer 78 (1998) 1442-1448
20. Johnson E.M., and Deen W.M. Hydraulic permeability of agarose gel. AIChE Journal 42 (1996) 1220-1224
21. Swabb E.A., Wei J., and Gullino P.M. Diffusion and convection in normal and neoplastic tissues. Cancer Research 34 (1974) 2814-2822
22. Neeves K.B., Lo C.T., Foley C.P., Saltzman W.M., and Olbricht W.L. Fabrication and characterization of microfluidic probes for convection enhanced delivery. Journal of Controlled Release 111 (2006) 252-262
23. Bobo R.H., Laske D.W., Akbasak A., Morrison P.F., Dedrick R.L., and Oldfield E.H. Convection-enhanced delivery of macromolecules in the brain. Proceedings of the National Academy of Sciences of the United States of America 91 (1994) 2076-2080
24. Basser P.J. Interstitial pressure, volume, and flow during infusion into brain tissue. Microvascular Research 44 (1992) 143-165
25. Paulson O.B., Hertz M.M., Bolwig T.G., and Lassen N.A. Filtration and diffusion of water across the blood-brain barrier in man. Microvascular Research 13 (1977) 113-124
26. Fraser P.A., and Dallas A.D. Measurement of filtration coefficient cerebral microvessels of the frog. Journal of Physiology 423 (1990) 343-361
27. Golan D.E., Tashjian A.H., Armstrong E., Galanter J.M., Armstrong A.W., Arnaout R.A., and Rose H.S. Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy (2008), Lippincot Williams & Wilkins, Baltimore MD 58-59
28. Kuh H.J., Jang S.H., Wientjes M.G., and Jessie Au L.S. Computational model of intracellular pharmacokinetics of paclitaxel. The Journal of Pharmacology and Experimental Therapeutics 293 (2000) 761-770
29. Wishart D.S., Knox C., Guo A.C., Shrivastava S., Hassanali M., Stothard P., Chang Z., and Woolsey J. Drug Bank: a comprehensive resource for in silico drug discovery and exploration. Nucleic Acids Research 34 (2006) D668-D672
30. De Sousa Maia M.B., Saivin S., Chatelut E., Malmary M.F., and Houin G. In vitro and in vivo protein binding of methotrexate assessed by microdialysis. International Journal of Clinical Pharamacology and Therapeutics 34 (1996) 335-341
31. Hand C.M., Vender J.R., and Black P. Chemotherapy in experimental brain tumor, part1 1: in vitro colorimetric MTT assay. Journal of Neuro-Oncology 36 (1998) 1-6
32. Deen W.M. Analysis of Transport Phenomena (1998), Oxford University Press, New York 181-184
33. Arifin D.Y., Lee L.Y., and Wang C.H. Mathematical modeling and simulation of drug release from microspheres: implications to drug delivery systems. Advanced Drug Delivery Reviews 58 (2006) 1274-1325
34. Li K.W., Dang W., Tyler B.M., Troiano G., Tihan T., Brem H., and Walter K.A. Polilactofate microspheres for paclitaxel delivery to central nervous system malignancies. Clinical Cancer Research 9 (2003) 3441-3447
35. Linninger A.A., Somayaji M.R., Mekarski M., and Zhang L. Prediction of convection-enhanced drug delivery to the human brain. Journal of Theoretical Biology 25 (2008) 125-138
36. Zhao J., Salmon H., and Sarntinoranont M. Effect of heterogeneous vasculature on interstitial transport within a solid tumor. Microvascular Research 72 (2007) 224-236