Keeping the beat: Life without SERCA - Is it possible?

Journal of Molecular and Cellular Cardiology

Volumn 47, Issue 2, 2009, Pages 171-173

  Trafford, Andrew W ^a   Lederer, W Jonathan ^b   Sobie, Eric A ^b,c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM TRANSPORT; COMPUTER MODEL; EDITORIAL; EXCITATION CONTRACTION COUPLING; HEART MUSCLE CONTRACTILITY; HEART RATE; MORPHOLOGICAL ADAPTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOPLASMIC RETICULUM;

ANIMALS; CALCIUM; COMPUTATIONAL BIOLOGY; HEART; MICE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; TAMOXIFEN;

EID: 67649111108     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.05.005     Document Type: Editorial

References (28)

1. Trafford A.W., Díaz M.E., O'Neill S.C., and Eisner D.A. Integrative analysis of calcium signalling in cardiac muscle. Front. Biosci. 6 (2002) D53-D64
2. Bers D.M. Excitation-Contraction Coupling and Cardiac Contractile Force. 2 ed (2001), Kluwer Academic Publishers, Dordrecht/Boston/London
3. Cheng H., Lederer W.J., and Cannell M.B. Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262 (1993) 740-744
4. López-López J.R., Shacklock P.S., Balke C.W., and Wier W.G. Local calcium transients triggered by single L-type calcium channel currents in cardiac cells. Science 268 (1995) 1042-1045
5. Cannell M.B., Cheng H., and Lederer W.J. The control of calcium release in heart muscle. Science 268 (1995) 1045-1049
6. Negretti N., O'Neill S.C., and Eisner D.A. The relative contributions of different intracellular and sarcolemmal systems to relaxation in rat ventricular myocytes. Cardiovasc. Res. 27 (1993) 1826-1830
7. Bassani J.W.M., Bassani R.A., and Bers D.M. Relaxation in rabbit and rat cardiac cells: species-dependant differences in cellular mechanisms. J. Physiol. (Lond). 476 (1994) 279-293
8. 2+ in cardiac hypertrophy. Cardiovasc. Res. 62 (2004) 538-547
9. O'Rourke B., Kass D.A., Tomaselli G.F., Kaab S., Tunin R., and Marban E. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I Experimental studies. Circ. Res. 84 (1999) 562-570
10. 2+ content in isolated failing and nonfailing human myocardium. Circ. Res. 85 (1999) 38-46
11. Del Monte F., Harding S.E., Schmidt U., Matsui T., Kang Z.B., Dec G.W., et al. Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a. Circulation 100 (1999) 2308-2311
12. Andersson K.V., Birkeland J.A.K., Finsen A.V., Louch W.E., Sjaastad I., Wang Y., et al. Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene. J Mol Cell Cardiol. 47 (2009) 180-187
13. 2+ content in cardiac myocytes. Am. J. Physiol. 268 (1995) C1313-C1329
14. 2+ current. Circ. Res. 88 (2001) 195-201
15. 2+ exchange: cardiac specific knockout of NCX1. Circ. Res. 95 (2004) 604-611
16. to,f and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction. Circ. Res. 97 (2005) 1342-1350
17. Lakatta E.G., and DiFrancesco D. What keeps us ticking: a funny current, a calcium clock, or both?. J Mol Cell Cardiol. 47 (2009) 157-170
18. 2+ release in rat ventricular myocytes. Pflügers Archiv. 434 (1997) 852-854
19. Cheng H., and Lederer W.J. Calcium Sparks Physiol. Rev. 88 (2008) 1491-1545
20. Oceandy D., Cartwright E.J., Emerson M., Prehar S., Baudoin F.M., Zi M., et al. Neuronal Nitric Oxide Synthase Signaling in the Heart Is Regulated by the Sarcolemmal Calcium Pump 4b. Circulation 115 (2007) 483-492
21. 2+-ATPase isoform 2 (SERCA2) gene. J. Biol. Chem. 274 (1999) 2556-2562
22. Bondarenko V.E., Szigeti G.P., Bett G.C., Kim S.J., and Rasmusson R.L. Computer model of action potential of mouse ventricular myocytes. Am. J. Physiol. Heart Circ. Physiol. 287 (2004) H1378-H1403
23. i. J. Physiol. (Lond) 585 (2007) 579-592
24. 2+ release and vulnerability to arrhythmias. J. Cardiovasc. Electrophysiol. 17 Suppl 1 (2006) S64-S70
25. i. J. Physiol. (Lond) 585 (2007) 579-592
26. 2+ transients in mouse ventricular myocytes. J. Physiol. (Lond) 543 (2002) 889-898
27. 2+ signaling during excitation-contraction coupling in neonate cardiac myocytes. Cell Calcium 41 (2007) 13-25
28. Wang L.J., and Sobie E.A. Mathematical model of the neonatal mouse ventricular action potential. Am. J. Physiol. Heart Circ. Physiol. 294 (2008) H2565-H2575