Individualised dosing of amikacin in neonates: A pharmacokinetic/ pharmacodynamic analysis

European Journal of Clinical Pharmacology

Volumn 65, Issue 7, 2009, Pages 705-713

  Sherwin, Catherine M T ^a   Svahn, Sofia ^c   Van Der Linden, Antje ^b   Broadbent, Roland S ^b   Medlicott, Natalie J ^d   Reith, David M ^b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c UPPSALA UNIVERSITY   (Sweden)

^d UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Amikacin; Neonates; Pharmacodynamics; Population pharmacokinetics

Indexed keywords

AMIKACIN; VANCOMYCIN;

ARTICLE; BIRTH WEIGHT; CONTINUOUS INFUSION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; GESTATIONAL AGE; GROUPS BY AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEWBORN; NEWBORN SEPSIS; PHARMACODYNAMICS; PRIORITY JOURNAL; RECOMMENDED DRUG DOSE; SIMULATION; TREATMENT FAILURE;

AMIKACIN; ANTI-BACTERIAL AGENTS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; GESTATIONAL AGE; HUMANS; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; INFANT, PREMATURE; INFUSIONS, INTRAVENOUS; MENSTRUATION; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; REPRODUCIBILITY OF RESULTS; RISK FACTORS; SEPSIS; TIME FACTORS; TREATMENT FAILURE;

EID: 67649088064     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-009-0637-4     Document Type: Article

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