Determination of population pharmacokinetic parameters for amikacin in neonates using mixed-effect models

European Journal of Clinical Pharmacology

Volumn 53, Issue 5, 1998, Pages 337-341

  Botha, J H ^a   Du Preez, M J ^a   Miller, R ^b,d   Adhikari, M ^c  

^a Medical School   (South Africa)

^b UNIVERSITY OF KWAZULU NATAL   (South Africa)

^c UNIVERSITY OF NATAL   (South Africa)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Amikacin; Neonate; NONMEM; Pharmacokinetics

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE;

ARTICLE; BIRTH WEIGHT; BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; GESTATIONAL AGE; GRAM NEGATIVE INFECTION; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; NEWBORN; PRIORITY JOURNAL; SOUTH AFRICA;

AFRICAN CONTINENTAL ANCESTRY GROUP; AMIKACIN; ANTI-BACTERIAL AGENTS; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; MALE; METABOLIC CLEARANCE RATE; MODELS, STATISTICAL; SEX FACTORS;

EID: 0031914179     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050389     Document Type: Article

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