메뉴 건너뛰기




Volumn 68, Issue 6, 2009, Pages 1022-1029

Exposure to nuclear antigens contributes to the induction of humoral autoimmunity during tumour necrosis factor alpha blockade

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; CASPASE 3 INHIBITOR; CELL NUCLEUS ANTIGEN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; ETANERCEPT; IMMUNOGLOBULIN M ANTIBODY; INFLIXIMAB; INTERFERON; NUCLEOSOME ANTIBODY; SORAFENIB; TUMOR NECROSIS FACTOR ALPHA;

EID: 67449164836     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2008.093724     Document Type: Article
Times cited : (25)

References (53)
  • 1
    • 0041689676 scopus 로고    scopus 로고
    • Predominant autoantibody production by early human B cell precursors
    • DOI 10.1126/science.1086907
    • Wardemann H, Yurasov S, Schaefer A, Young JW, Meffre E, Nussenzweig MC. Predominant autoantibody production by early human B cell precursors. Science 2003;301:1374-1377 (Pubitemid 37075812)
    • (2003) Science , vol.301 , Issue.5638 , pp. 1374-1377
    • Wardemann, H.1    Yurasov, S.2    Schaefer, A.3    Young, J.W.4    Meffre, E.5    Nussenzweig, M.C.6
  • 2
    • 34548536750 scopus 로고    scopus 로고
    • B-Cell Self-Tolerance in Humans
    • DOI 10.1016/S0065-2776(07)95003-8, PII S0065277607950038
    • Wardemann H, Nussenzweig MC. B-cell self-tolerance in humans. Adv Immunol 2007;95:83-110. (Pubitemid 47381589)
    • (2007) Advances in Immunology , vol.95 , pp. 83-110
    • Wardemann, H.1    Nussenzweig, M.C.2
  • 10
    • 0031825552 scopus 로고    scopus 로고
    • Systemic exposure to irradiated apoptotic cells induces autoantibody production
    • DOI 10.1084/jem.188.2.387
    • Mevorach D, Zhou JL, Song X, Elkon KB. Systemic exposure to irradiated apoptotic cells induces autoantibody production. J Exp Med 1998;188:387-392 (Pubitemid 28357766)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.2 , pp. 387-392
    • Mevorach, D.1    Zhou, J.L.2    Song, X.3    Elkon, K.B.4
  • 12
    • 22244478648 scopus 로고    scopus 로고
    • Infliximab, but not etanercept, induces IgM anti-double-stranded DNA autoantibodies as main antinuclear reactivity: Biologic and clinical implications in autoimmune arthritis
    • DOI 10.1002/art.21190
    • De Rycke L, Baeten D, Kruithof E, Van den Bosch F, Veys EM, De Keyser F. Infliximab, but not etanercept, induces IgM anti-double-stranded DNA autoantibodies as main antinuclear reactivity: biologic and clinical implications in autoimmune arthritis. Arthritis Rheum 2005;52:2192-2201 (Pubitemid 40994342)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.7 , pp. 2192-2201
    • De Rycke, L.1    Baeten, D.2    Kruithof, E.3    Van Bosch, F.D.4    Veys, E.M.5    De Keyser, F.6
  • 14
    • 12344297311 scopus 로고    scopus 로고
    • Evidence that anti-tumor necrosis factor therapy with both etanercept and infliximab induces apoptosis in macrophages, but not lymphocytes, in rheumatoid arthritis joints: Extended report
    • Catrina AI, Trollmo C, af Klint E, Engstrom M, Lampa J, Hermansson Y, et al. Evidence that anti-tumor necrosis factor therapy with both etanercept and infliximab induces apoptosis in macrophages, but not lymphocytes, in rheumatoid arthritis joints: extended report. Arthritis Rheum 2005;52:61-72.
    • (2005) Arthritis Rheum , vol.52 , pp. 61-72
    • Catrina, A.I.1    Trollmo, C.2    Af Klint, E.3    Engstrom, M.4    Lampa, J.5    Hermansson, Y.6
  • 15
    • 19144369300 scopus 로고    scopus 로고
    • Infliximab induces apoptosis of monocytes and T lymphocytes in a human-mouse chimeric model
    • DOI 10.1016/j.clim.2005.01.007, PII S152166160500029X
    • Shen C, Maerten P, Geboes K, Van AG, Rutgeerts P, Ceuppens JL. Infliximab induces apoptosis of monocytes and T lymphocytes in a human-mouse chimeric model. Clin Immunol 2005;115:250-259 (Pubitemid 40716048)
    • (2005) Clinical Immunology , vol.115 , Issue.3 , pp. 250-259
    • Shen, C.1    Maerten, P.2    Geboes, K.3    Van Assche, G.4    Rutgeerts, P.5    Ceuppens, J.L.6
  • 17
    • 34249707811 scopus 로고    scopus 로고
    • TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
    • DOI 10.1038/nm1590, PII NM1590
    • Baccala R, Hoebe K, Kono DH, Beutler B, Theofilopoulos AN. TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity. Nat Med 2007;13:543-551 (Pubitemid 46828489)
    • (2007) Nature Medicine , vol.13 , Issue.5 , pp. 543-551
    • Baccala, R.1    Hoebe, K.2    Kono, D.H.3    Beutler, B.4    Theofilopoulos, A.N.5
  • 18
    • 34347366358 scopus 로고    scopus 로고
    • Dendritic cells and interferon-mediated autoimmunity
    • DOI 10.1016/j.biochi.2007.04.013, PII S0300908407001083
    • Gottenberg JE, Chiocchia G. Dendritic cells and interferon-mediated autoimmunity. Biochimie 2007;89:856-871 (Pubitemid 47008948)
    • (2007) Biochimie , vol.89 , Issue.6-7 , pp. 856-871
    • Gottenberg, J.-E.1    Chiocchia, G.2
  • 19
    • 33750378268 scopus 로고    scopus 로고
    • Systemic lupus erythematosus: All roads lead to type I interferons
    • DOI 10.1016/j.coi.2006.09.014, PII S0952791506001993
    • Pascual V, Farkas L, Banchereau J. Systemic lupus erythematosus: all roads lead to type I interferons. Curr Opin Immunol 2006;18:676-682 (Pubitemid 44635182)
    • (2006) Current Opinion in Immunology , vol.18 , Issue.6 , pp. 676-682
    • Pascual, V.1    Farkas, L.2    Banchereau, J.3
  • 20
    • 0026003027 scopus 로고
    • The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy
    • Dougados M, van der Linden S, Juhlin R, Huitfeldt B, Amor B, Calin A, et al. The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum 1991;34:1218-1227
    • (1991) Arthritis Rheum , vol.34 , pp. 1218-1227
    • Dougados, M.1    Van Der Linden, S.2    Juhlin, R.3    Huitfeldt, B.4    Amor, B.5    Calin, A.6
  • 22
    • 0035150659 scopus 로고    scopus 로고
    • Immunomodulatory effects of anti-tumor necrosis factor alpha therapy on synovium in spondylarthropathy: Histologic findings in eight patients from an open-label pilot study
    • DOI 10.1002/1529-0131(200101)44:1<186::AID-ANR25>3.0.CO;2-B
    • Baeten D, Kruithof E, Van den Bosch F, Demetter P, Van Damme N, Cuvelier C, et al. Immunomodulatory effects of anti-tumor necrosis factor alpha therapy on synovium in spondylarthropathy: histologic findings in eight patients from an open-label pilot study. Arthritis Rheum 2001;44:186-195 (Pubitemid 32113134)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.1 , pp. 186-195
    • Baeten, D.1    Kruithof, E.2    Van Bosch, F.D.3    Demetter, P.4    Van Damme, N.5    Cuvelier, C.6    De Vos, M.7    Mielants, H.8    Veys, E.M.9    De Keyser, F.10
  • 24
    • 0036676818 scopus 로고    scopus 로고
    • Comparison of synovial tissues from the knee joints and the small joints of rheumatoid arthritis patients: Implications for pathogenesis and evaluation of treatment
    • DOI 10.1002/art.10556
    • Kraan MC, Reece RJ, Smeets TJ, Veale DJ, Emery P, Tak PP. Comparison of synovial tissues from the knee joints and the small joints of rheumatoid arthritis patients: implications for pathogenesis and evaluation of treatment. Arthritis Rheum 2002;46:2034-2038 (Pubitemid 34894757)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.8 , pp. 2034-2038
    • Kraan, M.C.1    Reece, R.J.2    Smeets, T.J.M.3    Veale, D.J.4    Emery, P.5    Tak, P.P.6
  • 28
    • 33745034931 scopus 로고    scopus 로고
    • Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies
    • DOI 10.1002/art.21890
    • Hua J, Kirou K, Lee C, Crow MK. Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies. Arthritis Rheum 2006;54:1906-1916 (Pubitemid 43877940)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.6 , pp. 1906-1916
    • Hua, J.1    Kirou, K.2    Lee, C.3    Crow, M.K.4
  • 29
    • 37149024418 scopus 로고    scopus 로고
    • Augmented interferon-alpha pathway activation in patients with Sjogren's syndrome treated with etanercept
    • DOI 10.1002/art.23062
    • Mavragani CP, Niewold TB, Moutsopoulos NM, Pillemer SR, Wahl SM, Crow MK. Augmented interferon-alpha pathway activation in patients with Sjogren's syndrome treated with etanercept. Arthritis Rheum 2007;56:3995-4004. (Pubitemid 350262327)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.12 , pp. 3995-4004
    • Mavragani, C.P.1    Niewold, T.B.2    Moutsopoulos, N.M.3    Pillemer, S.R.4    Wahl, S.M.5    Crow, M.K.6
  • 30
    • 0043074682 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha blockade reduces the synovial cell infiltrate early after initiation of treatment, but apparently not by induction of apoptosis in synovial tissue
    • DOI 10.1002/art.11098
    • Smeets TJ, Kraan MC, van Loon ME, Tak PP. Tumor necrosis factor alpha blockade reduces the synovial cell infiltrate early after initiation of treatment, but apparently not by induction of apoptosis in synovial tissue. Arthritis Rheum 2003;48:2155-2162 (Pubitemid 36959195)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.8 , pp. 2155-2162
    • Smeets, T.J.M.1    Kraan, M.C.2    Van Loon, M.E.3    Tak, P.-P.4
  • 31
    • 3042785960 scopus 로고    scopus 로고
    • Early effects of tumour necrosis factor alpha blockade on skin and synovial tissue in patients with active psoriasis and psoriatic arthritis
    • DOI 10.1136/ard.2003.018085
    • Goedkoop AY, Kraan MC, Teunissen MB, Picavet DI, de Rie MA, Bos JD, et al. Early effects of tumour necrosis factor alpha blockade on skin and synovial tissue in patients with active psoriasis and psoriatic arthritis. Ann Rheum Dis 2004;63:769-773 (Pubitemid 38850446)
    • (2004) Annals of the Rheumatic Diseases , vol.63 , Issue.7 , pp. 769-773
    • Goedkoop, A.Y.1    Kraan, M.C.2    Teunissen, M.B.M.3    Picavet, D.I.4    De Rie, M.A.5    Bos, J.D.6    Tak, P.P.7
  • 32
    • 38549176118 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonist mechanisms of action: A comprehensive review
    • Tracey D, Klareskog L, Sasso EH, Salfeld J, Tak PP. Tumor necrosis factor antagonist mechanisms of action: A comprehensive review. Pharmacol Therapeut 2008;117:244-279
    • (2008) Pharmacol Therapeut , vol.117 , pp. 244-279
    • Tracey, D.1    Klareskog, L.2    Sasso, E.H.3    Salfeld, J.4    Tak, P.P.5
  • 33
    • 33748447541 scopus 로고    scopus 로고
    • Type I Interferon in Systemic Lupus Erythematosus and Other Autoimmune Diseases
    • DOI 10.1016/j.immuni.2006.08.010, PII S1074761306003955
    • Banchereau J, Pascual V. Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity 2006;25:383-392 (Pubitemid 44354221)
    • (2006) Immunity , vol.25 , Issue.3 , pp. 383-392
    • Banchereau, J.1    Pascual, V.2
  • 34
    • 0035423557 scopus 로고    scopus 로고
    • An etiopathogenic role for the type I IFN system in SLE
    • DOI 10.1016/S1471-4906(01)01955-X, PII S147149060101955X
    • Ronnblom L, Alm GV. An etiopathogenic role for the type I IFN system in SLE. Trends Immunol 2001;22:427-431 (Pubitemid 32709976)
    • (2001) Trends in Immunology , vol.22 , Issue.8 , pp. 427-431
    • Ronnblom, L.1    Alm, G.V.2
  • 36
    • 0346461662 scopus 로고    scopus 로고
    • Defective mucosal T cell death is sustainably reverted by infliximab in a caspase dependent pathway in Crohn's disease
    • DOI 10.1136/gut.53.1.70
    • Di Sabatino A., Ciccocioppo R, Cinque B, Millimaggi D, Morera R, Ricevuti L, et al. Defective mucosal T cell death is sustainably reverted by infliximab in a caspase dependent pathway in Crohn's disease. Gut 2004;53:70-77 (Pubitemid 38083013)
    • (2004) Gut , vol.53 , Issue.1 , pp. 70-77
    • Di Sabatino, A.1    Ciccocioppo, R.2    Cinque, B.3    Millimaggi, D.4    Morera, R.5    Ricevuti, L.6    Cifone, M.G.7    Corazza, G.R.8
  • 37
    • 0034754480 scopus 로고    scopus 로고
    • Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathway
    • Lugering A, Schmidt M, Lugering N, Pauels HG, Domschke W, Kucharzik T. Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathway. Gastroenterology 2001;121:1145-1157 (Pubitemid 33022095)
    • (2001) Gastroenterology , vol.121 , Issue.5 , pp. 1145-1157
    • Lugering, A.1    Schmidt, M.2    Lugering, N.3    Pauels, H.-G.4    Domschke, W.5    Kucharzik, T.6
  • 39
    • 9144239396 scopus 로고    scopus 로고
    • Effects of infliximab on apoptosis and reverse signaling of monocytes from healthy individuals and patients with Crohn's disease
    • DOI 10.1097/00054725-200411000-00015
    • Ringheanu M, Daum F, Markowitz J, Levine J, Katz S, Lin X, et al. Effects of infliximab on apoptosis and reverse signaling of monocytes from healthy individuals and patients with Crohn's disease. Inflamm Bowel Dis 2004;10:801-810 (Pubitemid 39545226)
    • (2004) Inflammatory Bowel Diseases , vol.10 , Issue.6 , pp. 801-810
    • Ringheanu, M.1    Daum, F.2    Markowitz, J.3    Levine, J.4    Katz, S.5    Lin, X.6    Silver, J.7
  • 40
    • 0036151047 scopus 로고    scopus 로고
    • Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease
    • ten Hove T, van Montfrans C, Peppelenbosch MP, Van Deventer SJ. Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease. Gut 2002;50:206-211
    • (2002) Gut , vol.50 , pp. 206-211
    • Ten Hove, T.1    Van Montfrans, C.2    Peppelenbosch, M.P.3    Van Deventer, S.J.4
  • 41
    • 0034761594 scopus 로고    scopus 로고
    • Transmembrane TNF-alpha, induction of apoptosis, and the efficacy of TNF-targeting therapies in Crohn's disease
    • Van Deventer SJ. Transmembrane TNF-alpha, induction of apoptosis, and the efficacy of TNF-targeting therapies in Crohn's disease. Gastroenterology 2001;121:1242-1246
    • (2001) Gastroenterology , vol.121 , pp. 1242-1246
    • Van Deventer, S.J.1
  • 42
    • 34547197343 scopus 로고    scopus 로고
    • The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress
    • DOI 10.1128/MCB.01080-06
    • Rahmani M, Davis EM, Crabtree TR, Habibi JR, Nguyen TK, Dent P, et al. The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress. Mol Cell Biol 2007;27:5499-5513 (Pubitemid 47124402)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.15 , pp. 5499-5513
    • Rahmani, M.1    Davis, E.M.2    Crabtree, T.R.3    Habibi, J.R.4    Nguyen, T.K.5    Dent, P.6    Grant, S.7
  • 43
    • 29144443475 scopus 로고    scopus 로고
    • Reduced uptake of apoptotic cells by macrophages in systemic lupus erythematosus: Correlates with decreased serum levels of complement
    • DOI 10.1136/ard.2005.035733
    • Bijl M, Reefman E, Horst G, Limburg PC, Kallenberg CG. Reduced uptake of apoptotic cells by macrophages in systemic lupus erythematosus: correlates with decreased serum levels of complement. Ann Rheum Dis 2006;65:57-63. (Pubitemid 41815640)
    • (2006) Annals of the Rheumatic Diseases , vol.65 , Issue.1 , pp. 57-63
    • Bijl, M.1    Reefman, E.2    Horst, G.3    Limburg, P.C.4    Kallenberg, C.G.M.5
  • 44
    • 34249697078 scopus 로고    scopus 로고
    • The clearance of apoptotic cells by complement
    • DOI 10.1016/j.imbio.2006.11.005, PII S0171298506001409
    • Flierman R, Daha MR. The clearance of apoptotic cells by complement. Immunobiology 2007;212:363-370 (Pubitemid 46825236)
    • (2007) Immunobiology , vol.212 , Issue.4-5 , pp. 363-370
    • Flierman, R.1    Daha, M.R.2
  • 45
    • 54349096879 scopus 로고    scopus 로고
    • IgG autoantibodies bound to surfaces of necrotic cells and complement C4 comprise the phagocytosis promoting activity for necrotic cells of SLE sera
    • Grossmayer GE, Munoz LE, Weber CK, Franz S, Voll RE, Kern PM, et al. IgG autoantibodies bound to surfaces of necrotic cells and complement C4 comprise the phagocytosis promoting activity for necrotic cells of SLE sera. Ann Rheum Dis 2008;67:1626-1632
    • (2008) Ann Rheum Dis , vol.67 , pp. 1626-1632
    • Grossmayer, G.E.1    Munoz, L.E.2    Weber, C.K.3    Franz, S.4    Voll, R.E.5    Kern, P.M.6
  • 46
    • 55849149761 scopus 로고    scopus 로고
    • Analysis of apoptosis in peripheral blood and synovial tissue very early after initiation of infliximab treatment in rheumatoid arthritis patients
    • Wijbrandts CA, Remans PH, Klarenbeek PL, Wouters D, van den Begh Weerman MA, Smeets TJ, et al. Analysis of apoptosis in peripheral blood and synovial tissue very early after initiation of infliximab treatment in rheumatoid arthritis patients. Arthritis Rheum 2008;58:3330-3339
    • (2008) Arthritis Rheum , vol.58 , pp. 3330-3339
    • Wijbrandts, C.A.1    Remans, P.H.2    Klarenbeek, P.L.3    Wouters, D.4    Van Den Begh Weerman, M.A.5    Smeets, T.J.6
  • 47
    • 0344405666 scopus 로고    scopus 로고
    • The expression of plasma nucleosomes in mice undergoing in vivo apoptosis
    • DOI 10.1016/S1521-6616(02)00027-X
    • Jiang N, Reich CF III, Monestier M, Pisetsky DS. The expression of plasma nucleosomes in mice undergoing in vivo apoptosis. Clin Immunol 2003;106:139-147 (Pubitemid 36369408)
    • (2003) Clinical Immunology , vol.106 , Issue.2 , pp. 139-147
    • Jiang, N.1    Reich III, C.F.2    Monestier, M.3    Pisetsky, D.S.4
  • 52
    • 35448963499 scopus 로고    scopus 로고
    • Homeostatic roles of naturally occurring antibodies: An overview
    • DOI 10.1016/j.jaut.2007.07.007, PII S0896841107000893, Pathophysiology of Autoimmune Desease
    • Lutz HU. Homeostatic roles of naturally occurring antibodies: an overview. J Autoimmun 2007;29:287-294 (Pubitemid 47633143)
    • (2007) Journal of Autoimmunity , vol.29 , Issue.4 , pp. 287-294
    • Lutz, H.U.1
  • 53
    • 16844377358 scopus 로고    scopus 로고
    • The role of IgM antibodies in the recognition and clearance of apoptotic cells
    • DOI 10.1016/j.molimm.2004.07.045
    • Peng Y, Kowalewski R, Kim S, Elkon KB. The role of IgM antibodies in the recognition and clearance of apoptotic cells. Mol Immunol 2005;42:781-787 (Pubitemid 40489027)
    • (2005) Molecular Immunology , vol.42 , Issue.7 , pp. 781-787
    • Peng, Y.1    Kowalewski, R.2    Kim, S.3    Elkon, K.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.