The relationship between European genetic admixture and body composition among Hispanics and Native Americans

American Journal of Human Biology

Volumn 21, Issue 3, 2009, Pages 377-382

  Klimentidis, Yann C ^a   Miller, G F ^a   Shriver, M D ^b  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMERICAN INDIAN; ANTHROPOMETRY; ARTICLE; BODY COMPOSITION; BODY FAT; BODY MASS; CONTROLLED STUDY; EDUCATION; ENVIRONMENTAL FACTOR; ETHNIC GROUP; EUROPE; FEMALE; GENETIC ANALYSIS; GENETIC VARIABILITY; HEALTH DISPARITY; HEALTH STATUS; HISPANIC; HUMAN; INCOME; MALE; PHENOTYPE; PHYSICAL ACTIVITY; POPULATION GENETICS; PREDICTOR VARIABLE; PRIORITY JOURNAL; SAMPLE SIZE; SELF REPORT; UNIVERSITY STUDENT; ADOLESCENT; ADULT; CAUCASIAN; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; NIGERIA; OBESITY; SIERRA LEONE; SPAIN; STATISTICAL MODEL; STUDENT; UNITED STATES;

ADIPOSITY; ADOLESCENT; BODY MASS INDEX; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HISPANIC AMERICANS; HUMANS; INDIANS, NORTH AMERICAN; LIKELIHOOD FUNCTIONS; MALE; NEW MEXICO; NIGERIA; SIERRA LEONE; SPAIN; STUDENTS; YOUNG ADULT;

EID: 67449136067     PISSN: 10420533     EISSN: 15206300     Source Type: Journal    
DOI: 10.1002/ajhb.20886     Document Type: Article

References (40)

1. American Diabetes Association. 2008. Available at: http:// www.diabetes.org/diabetes-statistics/prevalence.jsp.
2. Bates LM, Acevedo-Garcia D, Alegria M, Krieger N. 2008. Immigration and generational trends in body mass index and obesity in the United States: results of the National Latino and Asian American Survey, 2002-2003. Am J Public Health 98:70-77.
3. Bertoni B, Budowle B, Sans M, Barton SA, Chakraborty R. 2003. Admixture in Hispanics: distribution of ancestral population contributions in the Continental United States. Hum Biol 75:1-11.
4. Bonilla C, Parra EJ, Pfaff CL, Dios S, Marshall JA, Hamman RF, Ferrell RE, Hoggart CL, McKeigue PM, Shriver MD. 2004a. Admixture in the Hispanics of the San Luis Valley, Colorado, and its implications for complex trait gene mapping. Ann Hum Genet 68(Pt 2):139-153.
5. Bonilla C, Shriver MD, Parra EJ, Jones A, Fernandez JR. 2004b. Ancestral proportions and their association with skin pigmentation and bone mineral density in Puerto Rican women from New York City. Hum Genet 115:57-68.
6. Brutsaert TD, Parra E, Shriver M, Gamboa A, Palacios JA, Rivera M, Rodriguez I, Leon-Velarde F. 2004. Effects of birthplace and individual genetic admixture on lung volume and exercise phenotypes of Peruvian Quechua. Am J Phys Anthropol 123:390-398.
7. Burchard EG, Ziv E, Coyle N, Gomez SL, Tang H, Karter AJ, Mountain JL, Perez-Stable EJ, Sheppard D, Risch N. 2003. The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med 348:1170-1175.
8. Burrows NR, Geiss LS, Engelgau MM, Acton KJ. 2000. Prevalence of diabetes among Native Americans and Alaska Natives, 1990-1997: an increasing burden. Diabetes Care 23:1786-1790.
9. Chakraborty R, Ferrell RE, Stern MP, Haffner SM, Hazuda HP, Rosenthal M. 1986. Relationship of prevalence of non-insulin-dependent diabetes mellitus to Amerindian admixture in the Mexican Americans of San Antonio, Texas. Genet Epidemiol 3:435-454.
10. Choudhry S, Coyle NE, Tang H, Salari K, Lind D, Clark SL, Tsai HJ, Naqvi M, Phong A, Ung N, Matallana H, Avila PC, Casal J, Torres A, Nazario S, Castro R, Battle NC, Perez-Stable EJ, Kwok PY, Sheppard D, Shriver MD, Rodriguez-Cintron W, Risch N, Ziv E, Burchard EG;Genetics of Asthma in Latino Americans GALA Study. 2006. Population stratification confounds genetic association studies among Latinos. Hum Genet 118:652-664.
11. Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH. 2003. Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994. Arch Pediatr Adolesc Med 157:821-827.
12. Fernandez JR, Shriver MD, Beasley TM, Rafla-Demetrious N, Parra E, Albu J, Nicklas B, Ryan AS, McKeigue PM, Hoggart CL, Weinsier RL, Allison DB. 2003. Association of African genetic admixture with resting metabolic rate and obesity among women. Obes Res 11:904-911.
13. Ford ES, Giles WH, Dietz WH. 2002. Prevalence of the metabolic syndrome among US adults: Findings from the third National Health and Nutrition Examination Survey. JAMA 287:356-359.
14. Foster MW, Sharp RR. 2002. Race, ethnicity, and genomics: social classifications as proxies of biological heterogeneity. Genome Res 12:844-850.
15. Gonzalez Burchard E, Borrell LN, Choudhry S, Naqvi M, Tsai HJ, Rodriguez-Santana JR, Chapela R, Rogers SD, Mei R, Rodriguez-Cintron W, Arena JF, Kittles R, Perez-Stable EJ, Ziv E, Risch N. 2005. Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research. Am J Public Health 95:2161-2168.
16. Gower BA, Fernandez JR, Beasley TM, Shriver MD, Goran MI. 2003. Using genetic admixture to explain racial differences in insulin-related phenotypes. Diabetes 52:1047-1051.
17. Gravlee CC, Dressler WW. 2005. Skin pigmentation, self perceived color, and arterial blood pressure in Puerto Rico. Am J Hum Biol 17:195-206.
18. Halder I. 2005. Measuring and using individual genomic ancestry to study complex phenotypes. University Park, PA: Pennsylvania State University. p 317.
19. Halder I, Shriver MD. 2003. Measuring and using admixture to study the genetics of complex diseases. Hum Genomics 1:52-62.
20. Hanis CL, Chakraborty R, Ferrell RE, Schull WJ. 1986. Individual admixture estimates: Disease associations and individual risk of diabetes and gallbladder disease among Mexican-Americans in Starr County, Texas. Am J Phys Anthropol 70:433-441.
21. Klimentidis YC, Miller GF, Shriver MD. 2008. Genetic admixture, self-reported ethnicity, self-estimated admixture, and skin pigmentation among Hispanics and Native Americans. Am J Phys Anthropol DOI. 10. 1002/ ajpa.20945.
22. Lara M, Gamboa C, Kahramanian MI, Morales LS, Bautista DE. 2005. Acculturation and Latino health in the United States: a review of the literature and its sociopolitical context. Annu Rev Public Health 26:367-397.
23. Long JC. 1991. The genetic structure of admixed populations. Genetics 127:417-428.
24. Luizon MR, Mendes-Junior CT, De Oliveira SF, Simoes AL. 2008. Ancestry informative markers in Amerindians from Brazilian Amazon. Am J Hum Biol 20:86-90.
25. Martinez-Marignac VL, Valladares A, Cameron E, Chan A, Perera A, Globus-Goldberg R, Wacher N, Kumate J, McKeigue P, O'Donnell D, Shriver MD, Cruz M, Parra EJ. 2007. Admixture in Mexico City: implications for admixture mapping of type 2 diabetes genetic risk factors. Hum Genet 120:807-819.
26. Montalvo FF, Codina E. 2001. Skin color and Latinos in the United States. Ethnicities 1:321-341.
27. Paradies YC, Montoya MJ, Fullerton SM. 2007. Racialized genetics and the study of complex diseases: the thrifty genotype revisited. Perspect Biol Med 50:203-227.
28. Parra EJ, Hoggart CJ, Bonilla C, Dios S, Norris JM, Marshall JA, Hamman RF, Ferrell RE, McKeigue PM, Shriver MD. 2004. Relation of type 2 diabetes to individual admixture and candidate gene polymorphisms in the Hispanic American population of San Luis Valley, Colorado. J Med Genet 41:e116.
29. Permutt MA, Wasson J, Cox N. 2005. Genetic epidemiology of diabetes. J Clin Invest 115:1431-1439.
30. Reiner AP, Carlson CS, Ziv E, Iribarren C, Jaquish CE, Nickerson DA. 2007. Genetic ancestry, population sub-structure, and cardiovascular disease-related traits among African-American participants in the CARDIA Study. Hum Genet 121:565-575.
31. Risch N. 2006. Dissecting racial and ethnic differences. N Engl J Med 354: 408-411.
32. Risch N, Burchard E, Ziv E, Tang H. 2002. Categorization of humans in biomedical research: genes, race and disease. Genome Biol 3: Comment 2007.
33. Salari K, Choudhry S, Tang H, Naqvi M, Lind D, Avila PC, Coyle NE, Ung N, Nazario S, Casal J, Torres-Palacios A, Clark S, Phong A, Gomez I, Matallana H, Pérez-Stable EJ, Shriver MD, Kwok PY, Sheppard D, Rodriguez-Cintron W, Risch NJ, Burchard EG, Ziv E. 2005. Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics. Genet Epidemiol 29:76-86.
34. Sankar P. 2006. Hasty generalisation and exaggerated certainties: reporting genetic findings in health disparities research. N Genet Soc 25:249-264.
35. Shrewsbury V, Wardle J. 2008. Socioeconomic status and adiposity in childhood: a systematic review of cross-sectional studies 1990-2005. Obesity (Silver Spring) 16:275-284.
36. Sweeney C, Wolff RK, Byers T, Baumgartner KB, Giuliano AR, Herrick JS, Murtaugh MA, Samowitz WS, Slattery ML. 2007. Genetic admixture among Hispanics and candidate gene polymorphisms: potential for confounding in a breast cancer study? Cancer Epidemiol Biomarkers Prev 16:142-150.
37. Tang H, Jorgenson E, Gadde M, Kardia SL, Rao DC, Zhu X, Schork NJ, Hanis CL, Risch N. 2006. Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans. Hum Genet 119:624-633.
38. Wang J. 2003. Maximum-likelihood estimation of admixture proportions from genetic data. Genetics 164:747-765.
39. Williams RC, Long JC, Hanson RL, Sievers ML, Knowler WC. 2000. Individual estimates of European genetic admixture associated with lower body-mass index, plasma glucose, and prevalence of type 2 diabetes in Pima Indians. Am J Hum Genet 66:527-538.
40. Ziv E, John EM, Choudhry S, Kho J, Lorizio W, Perez-Stable EJ, Burchard EG. 2006. Genetic ancestry and risk factors for breast cancer among Latinas in the San Francisco Bay Area. Cancer Epidemiol Biomarkers Prev 15:1878-1885.