Glycoprotein L sets the neutralization profile of murid herpesvirus 4

Journal of General Virology

Volumn 90, Issue 5, 2009, Pages 1202-1214

  Gillet, Laurent ^a   Alenquer, Marta ^a   Glauser, Daniel L ^a   Colaco, Susanna ^a   May, Janet S ^a   Stevenson, Philip G ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLYCOPROTEIN; GLYCOPROTEIN 70; GLYCOPROTEIN B; GLYCOPROTEIN H; GLYCOPROTEIN L; HEPARAN SULFATE; HETERODIMER; UNCLASSIFIED DRUG; VIRUS ANTIBODY; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ARTICLE; ENDOCYTOSIS; ENDOSOME; FEMALE; GENETIC SUSCEPTIBILITY; HERPES VIRUS; MOUSE; MURID HERPESVIRUS 4; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; VIRION; VIRUS ATTACHMENT; VIRUS ENTRY; VIRUS IMMUNITY; VIRUS NEUTRALIZATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL LINE; CHO CELL; CRICETULUS; EPITHELIUM CELL; FIBROBLAST; HAMSTER; IMMUNOLOGY; MACROPHAGE; METABOLISM; PROTEIN BINDING; RHADINOVIRUS;

MURID HERPESVIRUS 4;

ANIMALS; ANTIBODIES, VIRAL; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; EPITHELIAL CELLS; FEMALE; FIBROBLASTS; GLYCOPROTEINS; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PROTEIN BINDING; RHADINOVIRUS; VIRAL ENVELOPE PROTEINS;

EID: 67449104510     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.008755-0     Document Type: Article

References (33)

1. Adler, H., Messerle, M., Wagner, M. & Koszinowski, U. H. (2000). Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome. J Virol 74, 6964-6974.
2. Atanasiu, D., Whitbeck, J. C., Cairns, T. M., Reilly, B., Cohen, G. H. & Eisenberg, R. J. (2007). Bimolecular complementation reveals that glycoproteins gB and gH/gL of herpes simplex virus interact with each other during cell fusion. Proc Natl Acad Sci U S A 104, 18718-18723.
3. Avitabile, E., Forghieri, C. & Campadelli-Fiume, G. (2007). Complexes between herpes simplex virus glycoproteins gD, gB, and gH detected in cells by complementation of split enhanced green fluorescent protein. J Virol 81, 11532-11537.
4. Borza, C. M. & Hutt-Fletcher, L. M. (2002). Alternate replication in B cells and epithelial cells switches tropism of Epstein-Barr virus. Nat Med 8, 594-599.
5. Browne, H., Bruun, B. & Minson, T. (2001). Plasma membrane requirements for cell fusion induced by herpes simplex virus type 1 glycoproteins gB, gD, gH and gL. J Gen Virol 82, 1419-1422.
6. de Lima, B. D., May, J. S. & Stevenson, P. G. (2004). Murine gammaherpesvirus 68 lacking gp150 shows defective virion release but establishes normal latency in vivo. J Virol 78, 5103-5112.
7. Gaspar, M., Gill, M. B., Lösing, J. B., May, J. S. & Stevenson, P. G. (2008). Multiple functions for ORF75c in murid herpesvirus-4 infection. PLoS One 3, e2781.
8. Gill, M. B., Gillet, L., Colaco, S., May, J. S., de Lima, B. D. & Stevenson, P. G. (2006). Murine gammaherpesvirus-68 glycoprotein H-glycoprotein L complex is a major target for neutralizing monoclonal antibodies. J Gen Virol 87, 1465-1475.
9. Gillet, L. & Stevenson, P. G. (2007a). Evidence for a multi-protein gamma-2-herpesvirus entry complex. J Virol 81, 13082-13091.
10. Gillet, L. & Stevenson, P. G. (2007b). Antibody evasion by the N terminus ofmurid herpesvirus-4 glycoprotein B. EMBO J 26, 5131-5142.
11. Gillet, L., Gill, M. B., Colaco, S., Smith, C. M. & Stevenson, P. G. (2006). Murine gammaherpesvirus-68 glycoprotein B presents a difficult neutralization target to monoclonal antibodies derived from infected mice. J Gen Virol 87, 3515-3527.
12. Gillet, L., Adler, H. & Stevenson, P. G. (2007a). Glycosaminoglycan interactions in murine gammaherpesvirus-68 infection. PLoS One 2, e347.
13. Gillet, L., May, J. S., Colaco, S. & Stevenson, P. G. (2007b). The murine gammaherpesvirus-68 gp150 acts as an immunogenic decoy to limit virion neutralization. PLoS One 2, e705.
14. Gillet, L., May, J. S., Colaco, S. & Stevenson, P. G. (2007c). Glycoprotein L disruption reveals two functional forms of the murine gammaherpesvirus 68 glycoprotein H. J Virol 81, 280-291.
15. Gillet, L., May, J. S. & Stevenson, P. G. (2007d). Post-exposure vaccination improves gammaherpesvirus neutralization. PLoS One 2, e899.
16. Gillet, L., Colaco, S. & Stevenson, P. G. (2008a). The murid herpesvirus-4 gH/gL binds to glycosaminoglycans. PLoS ONE 3, e1669.
17. Gillet, L., Colaco, S. & Stevenson, P. G. (2008b). Glycoprotein B switches conformation during murid herpesvirus 4 entry. J Gen Virol 89, 1352-1363.
18. Gillet, L., Colaco, S. & Stevenson, P. G. (2008c). The murid herpesvirus-4 gL regulates an entry-associated conformation change in gH. PLoS One 3, e2811.
19. Heldwein, E. E., Lou, H., Bender, F. C., Cohen, G. H., Eisenberg, R. J. & Harrison, S. C. (2006). Crystal structure of glycoprotein B from herpes simplex virus 1. Science 313, 217-220.
20. Inada, T., Chong, K. T. & Mims, C. A. (1985). Enhancing antibodies, macrophages and virulence in mouse cytomegalovirus infection. J Gen Virol 66, 871-878.
21. Kapadia, S. B., Molina, H., van Berkel, V., Speck, S. H. & Virgin, H. W. (1999). Murine gammaherpesvirus 68 encodes a functional regulator of complement activation. J Virol 73, 7658-7670.
22. Köhler, G. & Milstein, C. (1975). Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256, 495-497.
23. Lopes, F. B., Colaco, S., May, J. S. & Stevenson, P. G. (2004). Characterization of murine gammaherpesvirus 68 glycoprotein B. J Virol 78, 13370-13375.
24. Maidji, E., McDonagh, S., Genbacev, O., Tabata, T. & Pereira, L. (2006). Maternal antibodies enhance or prevent cytomegalovirus infection in the placenta by neonatal Fc receptor-mediated transcytosis. Am J Pathol 168, 1210-1226.
25. Mancini, G., Carbonara, A. O. & Heremans, J. F. (1965). Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry 2, 235-254.
26. Mark, L., Lee, W. H., Spiller, O. B., Villoutreix, B. O. & Blom, A. M. (2006). The Kaposi's sarcoma-associated herpesvirus complement control protein (KCP) binds to heparin and cell surfaces via positively charged amino acids in CCP1-2. Mol Immunol 43, 1665-1675.
27. May, J. S., Colaco, S. & Stevenson, P. G. (2005). Glycoprotein M is an essential lytic replication protein of the murine gammaherpesvirus 68. J Virol 79, 3459-3467.
28. Roche, S., Rey, F. A., Gaudin, Y. & Bressanelli, S. (2007). Structure of the prefusion form of the vesicular stomatitis virus glycoprotein G. Science 315, 843-848.
29. Roop, C., Hutchinson, L. & Johnson, D. C. (1993). A mutant herpes simplex virus type 1 unable to express glycoprotein L cannot enter cells, and its particles lack glycoprotein H. J Virol 67, 2285-2297.
30. Rosa, G. T., Gillet, L., Smith, C. M., de Lima, B. D. & Stevenson, P. G. (2007). IgG Fc receptors provide an alternative infection route for murine gamma-herpesvirus-68. PLoS One 2, e560.
31. Stevenson, P. G. & Doherty, P. C. (1999). Non-antigen-specific B-cell activation following murine gammaherpesvirus infection is CD4 independent in vitro but CD4 dependent in vivo. J Virol 73, 1075-1079.
32. Wang, D. & Shenk, T. (2005). Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropism. Proc Natl Acad Sci U S A 102, 18153-18158.
33. Zinkernagel, R. M. & Hengartner, H. (2006). Protective 'immunity' by pre-existent neutralizing antibody titers and preactivated T cells but not by so-called 'immunological memory'. Immunol Rev 211, 310-319.