-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100:57-70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
33645739790
-
Tumor stroma and regulation of cancer development
-
Tlsty TD, Coussens LM (2006) Tumor stroma and regulation of cancer development. Annu Rev Pathol 1:119-150
-
(2006)
Annu Rev Pathol
, vol.1
, pp. 119-150
-
-
Tlsty, T.D.1
Coussens, L.M.2
-
3
-
-
33746040164
-
The inflammatory tumor microenvironment and its impact on cancer development
-
de Visser KE, Coussens LM (2006) The inflammatory tumor microenvironment and its impact on cancer development. Contrib Microbiol 13:118-137
-
(2006)
Contrib Microbiol
, vol.13
, pp. 118-137
-
-
de Visser, K.E.1
Coussens, L.M.2
-
4
-
-
48149104816
-
Spontaneous immune responses to sporadic tumors: Tumor-promoting, tumor-protective or both?
-
de Visser KE (2008) Spontaneous immune responses to sporadic tumors: tumor-promoting, tumor-protective or both? Cancer Immunol Immunother 57:1531-1539
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 1531-1539
-
-
de Visser, K.E.1
-
5
-
-
0035901090
-
Inflammation and cancer: Back to Virchow?
-
Balkwill F, Mantovani A (2001) Inflammation and cancer: Back to Virchow? Lancet 357:539-545
-
(2001)
Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
6
-
-
0014887939
-
The concept of immunological surveillance
-
Burnet FM (1970) The concept of immunological surveillance. Prog Exp Tumor Res 13:1-27
-
(1970)
Prog Exp Tumor Res
, vol.13
, pp. 1-27
-
-
Burnet, F.M.1
-
7
-
-
47749139256
-
Cancer as an overhealing wound: An old hypothesis revisited
-
Schafer M, Werner S (2008) Cancer as an overhealing wound: An old hypothesis revisited. Nat Rev Mol Cell Biol 9:628-638
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 628-638
-
-
Schafer, M.1
Werner, S.2
-
9
-
-
17644394616
-
Smoldering and polarized inflammation in the initiation and promotion of malignant disease
-
Balkwill F, Charles KA, Mantovani A (2005) Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 7:211-217
-
(2005)
Cancer Cell
, vol.7
, pp. 211-217
-
-
Balkwill, F.1
Charles, K.A.2
Mantovani, A.3
-
10
-
-
9444265320
-
Gastric cancer originating from bone marrow-derived cells
-
Houghton J, Stoicov C, Nomura S et al (2004) Gastric cancer originating from bone marrow-derived cells. Science 306:1568-1571
-
(2004)
Science
, vol.306
, pp. 1568-1571
-
-
Houghton, J.1
Stoicov, C.2
Nomura, S.3
-
11
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten FR, Eckmann L, Greten TF et al (2004) IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118:285-296
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
-
12
-
-
4644324186
-
NFkappaB functions as a tumour promoter in inflammation-associated cancer
-
Pikarsky E, Porat RM, Stein I et al (2004) NFkappaB functions as a tumour promoter in inflammation-associated cancer. Nature 431:461-466
-
(2004)
Nature
, vol.431
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
-
13
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z (2002) Inflammation and cancer. Nature 420:860-867
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
15
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
Mantovani A, Sica A, Sozzani S et al (2004) The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25:677-686
-
(2004)
Trends Immunol
, vol.25
, pp. 677-686
-
-
Mantovani, A.1
Sica, A.2
Sozzani, S.3
-
16
-
-
0347123433
-
Tumour-educated ma cro phages promote tumour progression and metastasis
-
Pollard JW (2004) Tumour-educated ma cro phages promote tumour progression and metastasis. Nat Rev Cancer 4:71-78
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 71-78
-
-
Pollard, J.W.1
-
17
-
-
11144355004
-
VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment
-
Cursiefen C, Chen L, Borges LP et al (2004) VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest 113:1040-1050
-
(2004)
J Clin Invest
, vol.113
, pp. 1040-1050
-
-
Cursiefen, C.1
Chen, L.2
Borges, L.P.3
-
18
-
-
52049100352
-
Modulation of tumor associated macrophages in solid tumors
-
Lucas T, Abraham D, Aharinejad S (2008) Modulation of tumor associated macrophages in solid tumors. Front Biosci 13:5580-5588
-
(2008)
Front Biosci
, vol.13
, pp. 5580-5588
-
-
Lucas, T.1
Abraham, D.2
Aharinejad, S.3
-
19
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel T, Coukos G, Zou L et al (2004) Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 10:942-949
-
(2004)
Nat Med
, vol.10
, pp. 942-949
-
-
Curiel, T.1
Coukos, G.2
Zou, L.3
-
20
-
-
0036187615
-
The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
-
Bingle L, Brown NJ, Lewis CE (2002) The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies. J Pathol 196:254-265
-
(2002)
J Pathol
, vol.196
, pp. 254-265
-
-
Bingle, L.1
Brown, N.J.2
Lewis, C.E.3
-
21
-
-
0035911221
-
Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
-
Lin EY, Nguyen AV, Russell RG, Pollard JW (2001) Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 193:727-740
-
(2001)
J Exp Med
, vol.193
, pp. 727-740
-
-
Lin, E.Y.1
Nguyen, A.V.2
Russell, R.G.3
Pollard, J.W.4
-
22
-
-
0033151608
-
Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis
-
Coussens LM, Raymond WW, Bergers G et al (1999) Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes Dev 13:1382-1397
-
(1999)
Genes Dev
, vol.13
, pp. 1382-1397
-
-
Coussens, L.M.1
Raymond, W.W.2
Bergers, G.3
-
23
-
-
33847419143
-
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice
-
Guerra C, Schuhmacher AJ, Cañamero M et al (2007) Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice. Cancer Cell 11:291-302
-
(2007)
Cancer Cell
, vol.11
, pp. 291-302
-
-
Guerra, C.1
Schuhmacher, A.J.2
Cañamero, M.3
-
24
-
-
3042822267
-
Cancer and the chemokine network
-
Balkwill F (2004) Cancer and the chemokine network. Nat Rev Cancer 4:540-550
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 540-550
-
-
Balkwill, F.1
-
25
-
-
0028902228
-
CSF-1 and its receptor in ovarian, endometrial and breast cancer
-
Kacinski BM (1995) CSF-1 and its receptor in ovarian, endometrial and breast cancer. Ann Med 27:79-85
-
(1995)
Ann Med
, vol.27
, pp. 79-85
-
-
Kacinski, B.M.1
-
26
-
-
0036005888
-
Tumor necrosis factor or tumor promoting factor?
-
Balkwill F (2002) Tumor necrosis factor or tumor promoting factor? Cytokine Growth Factor Rev 13:135-141
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 135-141
-
-
Balkwill, F.1
-
27
-
-
1842586795
-
Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour development
-
Arnott CH, Scott KA, Moore RJ et al (2004) Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour development. Oncogene 23:1902-1910
-
(2004)
Oncogene
, vol.23
, pp. 1902-1910
-
-
Arnott, C.H.1
Scott, K.A.2
Moore, R.J.3
-
28
-
-
0037418208
-
IL-1 is required for tumor invasiveness and angiogenesis
-
Voronov E, Shouval DS, Krelin Y et al (2003) IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci U S A 100:2645-2650
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 2645-2650
-
-
Voronov, E.1
Shouval, D.S.2
Krelin, Y.3
-
29
-
-
0142250392
-
Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: A review of the rationale and clinical evidence
-
Trikha M, Corringham R, Klein B, Rossi JF (2003) Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: A review of the rationale and clinical evidence. Clin Cancer Res 9:4653-4665
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4653-4665
-
-
Trikha, M.1
Corringham, R.2
Klein, B.3
Rossi, J.F.4
-
30
-
-
0141540687
-
Enhancing radiotherapy with cyclooxygenase-2 enzyme inhibitors: A rational advance?
-
Choy H, Milas L (2003) Enhancing radiotherapy with cyclooxygenase-2 enzyme inhibitors: A rational advance? J Natl Cancer Inst 95:1440-1452
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 1440-1452
-
-
Choy, H.1
Milas, L.2
-
31
-
-
0141963117
-
Inhibitors of cyclo-oxygenase 2: A new class of anticancer agents?
-
Gasparini G, Longo R, Sarmiento R, Morabito A (2003) Inhibitors of cyclo-oxygenase 2: A new class of anticancer agents? Lancet Oncol 4:605-615
-
(2003)
Lancet Oncol
, vol.4
, pp. 605-615
-
-
Gasparini, G.1
Longo, R.2
Sarmiento, R.3
Morabito, A.4
-
32
-
-
0034665122
-
The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis
-
Jacoby RF, Seibert K, Cole CE et al (2000) The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. Cancer Res 60:5040-5044
-
(2000)
Cancer Res
, vol.60
, pp. 5040-5044
-
-
Jacoby, R.F.1
Seibert, K.2
Cole, C.E.3
-
33
-
-
19344365408
-
De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent
-
de Visser KE, Korets LV, Coussens LM (2005) De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent. Cancer Cell 7:411-423
-
(2005)
Cancer Cell
, vol.7
, pp. 411-423
-
-
de Visser, K.E.1
Korets, L.V.2
Coussens, L.M.3
-
34
-
-
0031428576
-
Lack of p53 and ras mutations in Helicobacter hepaticus-induced liver tumors in A/JCr mice
-
Sipowicz MA, Weghorst CM, Shiao Y-H et al (1997) Lack of p53 and ras mutations in Helicobacter hepaticus-induced liver tumors in A/JCr mice. Carcinogenesis 18:233-236
-
(1997)
Carcinogenesis
, vol.18
, pp. 233-236
-
-
Sipowicz, M.A.1
Weghorst, C.M.2
Shiao, Y.-H.3
-
36
-
-
40249109853
-
The IkappaB kinase - A bridge between inflammation and cancer
-
Karin M (2008) The IkappaB kinase - a bridge between inflammation and cancer. Cell Res 18:334-342
-
(2008)
Cell Res
, vol.18
, pp. 334-342
-
-
Karin, M.1
-
38
-
-
55749085109
-
Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer
-
Perez-Moreno M, Song W, Pasolli HA et al (2008) Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer. Proc Natl Acad Sci U S A 105:15399-15404
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 15399-15404
-
-
Perez-Moreno, M.1
Song, W.2
Pasolli, H.A.3
-
39
-
-
35848938280
-
p38alpha: A suppressor of cell proliferation and tumorigenesis
-
Hui L, Bakiri L, Stepniak E, Wagner EF (2007) p38alpha: A suppressor of cell proliferation and tumorigenesis. Cell Cycle 6:2429-2433
-
(2007)
Cell Cycle
, vol.6
, pp. 2429-2433
-
-
Hui, L.1
Bakiri, L.2
Stepniak, E.3
Wagner, E.F.4
-
40
-
-
7044274054
-
Mitogen activated protein kinases as targets for development of novel anti-inflammatory drugs
-
Karin M (2004) Mitogen activated protein kinases as targets for development of novel anti-inflammatory drugs. Ann Rheum Dis 63[Suppl 2]:iI62-ii64
-
(2004)
Ann Rheum Dis
, vol.63
, Issue.SUPPL. 2
-
-
Karin, M.1
-
41
-
-
0037130471
-
Tumour necrosis factor-alpha mediates tumour promotion via a PKC alpha- and AP-1-dependent pathway
-
Arnott CH, Scott KA, Moore RJ et al (2002) Tumour necrosis factor-alpha mediates tumour promotion via a PKC alpha- and AP-1-dependent pathway. Oncogene 21:4728-4738
-
(2002)
Oncogene
, vol.21
, pp. 4728-4738
-
-
Arnott, C.H.1
Scott, K.A.2
Moore, R.J.3
-
42
-
-
3042665905
-
Cyclooxygenase as a target in lung cancer
-
Brown JR, DuBois RN (2004) Cyclooxygenase as a target in lung cancer. Clin Cancer Res 10:4266s-4269s
-
(2004)
Clin Cancer Res
, vol.10
-
-
Brown, J.R.1
DuBois, R.N.2
-
43
-
-
0035198106
-
Role of cyclooxygenase inhibitors for the prevention of colorectal cancer
-
Stack E, DuBois RN (2001) Role of cyclooxygenase inhibitors for the prevention of colorectal cancer. Gastroenterol Clin North Am 30:1001-1010
-
(2001)
Gastroenterol Clin North Am
, vol.30
, pp. 1001-1010
-
-
Stack, E.1
DuBois, R.N.2
-
45
-
-
4944239035
-
An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis
-
Giraudo E, Inoue M, Hanahan D (2004) An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis. J Clin Invest 114:623-633
-
(2004)
J Clin Invest
, vol.114
, pp. 623-633
-
-
Giraudo, E.1
Inoue, M.2
Hanahan, D.3
-
46
-
-
0346365367
-
A chemokine receptor antagonist inhibits experimental breast tumor growth
-
Robinson SC, Scott KA, Wilson JL et al (2003) A chemokine receptor antagonist inhibits experimental breast tumor growth. Cancer Res 63:8360-8365
-
(2003)
Cancer Res
, vol.63
, pp. 8360-8365
-
-
Robinson, S.C.1
Scott, K.A.2
Wilson, J.L.3
-
47
-
-
43749098070
-
NF-kappaB and cancer-identifying targets and mechanisms
-
Naugler WE, Karin M (2008) NF-kappaB and cancer-identifying targets and mechanisms. Curr Opin Genet Dev 18:19-26
-
(2008)
Curr Opin Genet Dev
, vol.18
, pp. 19-26
-
-
Naugler, W.E.1
Karin, M.2
|