In vitro sensitivity of granulo-monocytic progenitors as a new toxicological cell system and endpoint in the ACuteTox Project

Toxicology and Applied Pharmacology

Volumn 238, Issue 2, 2009, Pages 111-119

  Cerrato, Laura ^a   Valeri, Antonio ^a   Bueren, Juan A ^a   Albella, Beatriz ^a  

^a CIEMAT   (Spain)

Author keywords

Alternative tests; CFU GM; Hematotoxicity; In vitro assays; Organ specific assay

Indexed keywords

ACETYLSALICYLIC ACID; AMIODARONE; CAFFEINE; CHLORAL HYDRATE; COLCHICINE; DIAZEPAM; DICHLORVOS; DIETHYLENE GLYCOL; DIGOXIN; ETHINYLESTRADIOL; FLUORIDE SODIUM; FLUOROURACIL; HEXACHLOROBENZENE; LINDANE; MALATHION; N,N DIMETHYLFORMAMIDE; NICOTINE; OCHRATOXIN; PARACETAMOL; PHYSOSTIGMINE; PROPRANOLOL; RIFAMPICIN; STRYCHNINE; TETRACYCLINE; THALLIUM SULFATE; VALPROIC ACID; VERAPAMIL; WARFARIN;

ARTICLE; BLOOD TOXICITY; CELL ASSAY; COLONY FORMING UNIT GM; CONTROLLED STUDY; CYTOTOXICITY; GRANULOCYTE; HUMAN; HUMAN CELL; IN VITRO STUDY; LC 50; MONOCYTE; MYELOID PROGENITOR CELL; TOXICITY TESTING;

ACUTE TOXICITY TESTS; ANIMAL TESTING ALTERNATIVES; BIOLOGICAL ASSAY; CELLS, CULTURED; COLONY-FORMING UNITS ASSAY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; EUROPEAN UNION; GRANULOCYTE-MACROPHAGE PROGENITOR CELLS; HUMANS; INDUSTRIAL WASTE; INHIBITORY CONCENTRATION 50; LETHAL DOSE 50; LINEAR MODELS; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SURVIVAL ANALYSIS;

ANIMALIA;

EID: 67449097468     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.05.005     Document Type: Article

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