Estrogen and gastrointestinal malignancy

Molecular and Cellular Endocrinology

Volumn 307, Issue 1-2, 2009, Pages 19-24

  Hogan, A M ^a,b   Collins, D ^a,b   Baird, A W ^b   Winter, D C ^a  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Colon; Esophagus; Estrogen; Gallbladder; Malignancy; Stomach

Indexed keywords

4 HYDROXYTAMOXIFEN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR BETA; TAMOXIFEN;

CANCER HORMONE THERAPY; CANCER INCIDENCE; CANCER INVASION; CANCER PREVENTION; CARCINOGENESIS; CLINICAL TRIAL; COLON CANCER; DIGESTIVE SYSTEM CANCER; ESOPHAGUS CANCER; GALLBLADDER CANCER; HORMONE SUBSTITUTION; HUMAN; METASTASIS POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; PROTEIN SYNTHESIS; REVIEW; SEX DIFFERENCE; STOMACH CANCER; STOMACH CARCINOMA; TRANSCRIPTION REGULATION;

COLONIC NEOPLASMS; ESOPHAGEAL NEOPLASMS; ESTROGENS; GALLBLADDER NEOPLASMS; GASTROINTESTINAL NEOPLASMS; HUMANS; STOMACH NEOPLASMS;

EID: 67349274950     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2009.03.016     Document Type: Review

References (81)

1. Akgun H., Lechago J., and Younes M. Estrogens receptor-beta is expressed in Barrett's metaplasia and associated adenocarcinoma of the esophagus. Anticancer Res. 22 3 (2002) 1459-1461
2. Alzamora R., and Harvey B.J. Direct binding and activation of protein kinase C isoforms by steroid hormones. Steroids 73 9-10 (2008) 885-888 Oct
3. Birge S.J. Hormone therapy and stroke. Clin. Obstet. Gynecol. 51 3 (2008) 581-591
4. Brenner H., Rothenbacher D., and Arndt V. Epidemiology of stomach cancer. Methods Mol. Biol. 472 (2009) 467-477
5. Brinton R.D. Estrogens regulation of glucose metabolism and mitochondrial function: therapeutic implications for prevention of Alzheimer's disease. Adv. Drug Deliv. Rev. 60 13-14 (2008) 1504-1511
6. Caiazza F., Galluzzo P., Lorenzetti S., and Marino M. 17Beta-estradiol induces ERbeta up-regulation via p38/MAPK activation in colon cancer cells. Biochem. Biophys. Res. Commun. 359 1 (2007) 102-107
7. Chandanos E., Lindblad M., Rubio C.A., Jia C., Warner M., Gustafsson J.A., and Lagergren J. Tamoxifen exposure in relation to gastric adenocarcinoma development. Eur. J. Cancer. 44 7 (2008) 1007-1014
8. Cook M.B., Wild C.P., and Forman D. A systematic review and meta-analysis of the sex ratio for Barrett's esophagus, erosive reflux disease, and nonerosive reflux disease. Am. J. Epidemiol. 1, 162 11 (2005) 1050-1061
9. Cui G., Yuan A., Qvigstad G., and Waldum H.L. Estrogens receptors are not expressed in esophagogastric carcinomas that come from a high incidence area of China. Hepatogastroenterology 48 39 (2001) 594-595
10. Deurveilher S., Cumyn E.M., Peers T., Rusak B., and Semba K. Estradiol replacement enhances sleep deprivation-induced c-Fos immunoreactivity in forebrain arousal regions of ovariectomized rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 295 4 (2008) R1328-R1340
11. Doolan C.M., and Harvey B.J. A Galphas protein-coupled membrane receptor, distinct from the classical oestrogen receptor, transduces rapid effects of oestradiol on [Ca2+]i in female rat distal colon. Mol. Cell. Endocrinol. 199 1-2 (2003) 87-103
12. Doolan C.M., Condliffe S.B., and Harvey B.J. Rapid non-genomic activation of cytosolic cyclic AMP-dependent protein kinase activity and [Ca(2+)](i) by 17beta-oestradiol in female rat distal colon. Br. J. Pharmacol. 129 7 (2000) 1375-1386
13. Enmark E., Pelto-Huikko M., Grandien K., Lagercrantz S., Lagercrantz J., Fried G., Nordenskjöld M., and Gustafsson J.A. Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern. J. Clin. Endocrinol. Metab. 82 12 (1997) 4258-4265
14. Foley E.F., Jazaeri A.A., Shupnik M.A., Jazaeri O., and Rice L.W. Selective loss of estrogen receptor beta in malignant human colon. Cancer Res. 60 2 (2000) 245-248
15. Francesca, C., Taddei, A., Degl'innocenti, D.R., Buccoliero, A.M., Bechi, P., Garbini, F., Gheri, C.F., Moncini, D., Cavallina, G., Marascio, L., Freschi, G., Taddei, G.L. Expression of estrogen beta receptors in colon cancer progression. Diagn. Mol. Pathol., 2007. [Epub ahead of print].
16. Freedman N.D., Chow W.H., Gao Y.T., Shu X.O., Ji B.T., Yang G., Lubin J.H., Li H.L., Rothman N., Zheng W., and Abnet C.C. Menstrual and reproductive factors and gastric cancer risk in a large prospective study of women. Gut 56 12 (2007) 1671-1677
17. Frise S., Kreiger N., Gallinger S., Tomlinson G., and Cotterchio M. Menstrual and reproductive risk factors and risk for gastric adenocarcinoma in women: findings from the Canadian national enhanced cancer surveillance system. Ann. Epidemiol. 16 12 (2006) 908-916
18. Furukawa H., Iwanaga T., Koyama H., and Taniguchi H. Effect of sex hormones on the experimental induction of cancer in rat stomach-a preliminary study. Digestion 23 3 (1982) 151-155
19. Gallus S., Negri E., Chatenoud L., Bosetti C., Franceschi S., and La Vecchia C. Post-menopausal hormonal therapy and gallbladder cancer risk. Int. J. Cancer 10, 99 5 (2002) 762-763
20. Galluzzo P., Caiazza F., Moreno S., and Marino M. Role of ERbeta palmitoylation in the inhibition of human colon cancer cell proliferation. Endocr. Relat. Cancer 14 1 (2007) 153-167
21. Gilad L.A., and Schwartz B. Association of estrogen receptor beta with plasma-membrane caveola components: implication in control of vitamin D receptor. J. Mol. Endocrinol. 38 6 (2007) 603-618
22. Harrison J.D., Watson S., and Morris D.L. The effect of sex hormones and tamoxifen on the growth of human gastric and colorectal cancer cell lines. Cancer 1, 63 11 (1989) 2148-2151
23. Harrison J.D., Morris D.L., Ellis I.O., Jones J.A., and Jackson I. The effect of tamoxifen and estrogen receptor status on survival in gastric carcinoma. Cancer 1, 64 5 (1989) 1007-1010
24. Harrison J.D., Jones J.A., Ellis I.O., and Morris D.L. Oestrogen receptor D5 antibody is an independent negative prognostic factor in gastric cancer. Br. J. Surg. 78 3 (1991) 334-336
25. Harvey B.J., Doolan C.M., Condliffe S.B., Renard C., Alzamora R., and Urbach V. Non-genomic convergent and divergent signalling of rapid responses to aldosterone and estradiol in mammalian colon. Steroids 67 6 (2002) 483-491
26. Hennessy B.A., Harvey B.J., and Healy V. 17beta-Estradiol rapidly stimulates c-fos expression via the MAPK pathway in T84 cells. Mol. Cell Endocrinol. 14, 229 1-2 (2005) 39-47
27. Hojo Y., Murakami G., Mukai H., Higo S., Hatanaka Y., Ogiue-Ikeda M., Ishii H., Kimoto T., and Kawato S. Estrogens synthesis in the brain-role in synaptic plasticity and memory. Mol. Cell Endocrinol. 290 1-2 (2008) 31-43
28. Hsu H.H., Cheng S.F., Wu C.C., Chu C.H., Weng Y.J., Lin C.S., Lee S.D., Wu H.C., Huang C.Y., and Kuo W.W. Apoptotic effects of over-expressed estrogen receptor-beta on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner. Chin. J. Physiol. 49 2 (2006) 110-116
29. Ikeguchi M., Fukuda K., Oka S., Yamaguchi K., Hisamitsu K., Tsujitani S., Sakatani T., Ueda T., and Kaibara N. Clinicopathological significance of cathepsin D expression in gastric adenocarcinoma. Oncology 61 1 (2001) 71-78
30. Jemal A., Siegel R., Ward E., Hao Y., Xu J., Murray T., and Thun M.J. Cancer statistics. CA Cancer J. Clin. 58 2 (2008) 71-96
31. Jick S.S., Hagberg K.W., Kaye J.A., and Jick H. Postmenopausal estrogen-containing hormone therapy and the risk of breast cancer. Obstet. Gynecol. 113 1 (2009) 74-80
32. Karat D., Brotherick I., Shenton B.K., Scott D., Raimes S.A., and Griffin S.M. Expression of oestrogen and progesterone receptors in gastric cancer, a flow cytometric study. Br. J. Cancer. 80 8 (1999) 1271-1274
33. Kennelly R., Kavanagh D.O., Hogan A.M., and Winter D.C. Oestrogen and the colon: potential mechanisms for cancer prevention. Lancet Oncol. 9 4 (2008) 385-391
34. Ko C.Y., Schmit P., Cheng L., and Thompson J.E. Estrogens receptors in gallbladder cancer: detection by an improved immunohistochemical assay. Am. Surg. 61 10 (1995) 930-933
35. Konstantinopoulos P.A., Kominea A., Vandoros G., Sykiotis G.P., Andricopoulos P., Varakis I., Sotiropoulou-Bonikou G., and Papavassiliou A.G. Oestrogen receptor beta (ERbeta) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation. Eur. J. Cancer 39 9 (2003) 1251-1258
36. Kuiper G.G., Enmark E., Pelto-Huikko M., Nilsson S., and Gustafsson J.A. Cloning of a novel receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. USA 93 12 (1996) 5925-5930
37. La Vecchia C., D'Avanzo B., Franceschi S., Negri E., Parazzini F., and Decarli A. Menstrual and reproductive factors and gastric-cancer risk in women. Int. J. Cancer 15, 59 6 (1994) 761-764
38. Lagergren J., and Nyrén O. Do sex hormones play a role in the etiology of esophageal adenocarcinoma? A new hypothesis tested in a population-based cohort of prostate cancer patients. Cancer Epidemiol. Biomarkers Prev. 7 10 (1998) 913-915
39. Lahm T., Crisostomo P.R., Markel T.A., Wang M., Weil B.R., Novotny N.M., and Meldrum D.R. The effects of estrogen on pulmonary artery vasoreactivity and hypoxic pulmonary vasoconstriction: potential new clinical implications for an old hormone. Crit. Care Med. 36 7 (2008) 2174-2183
40. Lambe M., Trichopoulos D., Hsieh C.C., Ekbom A., Adami H.O., and Pavia M. Parity and cancers of the gall bladder and the extrahepatic bile ducts. Int. J. Cancer 30, 54 6 (1993) 941-944
41. Lindblad M., Ye W., Rubio C., and Lagergren J. Estrogens and risk of gastric cancer: a protective effect in a nationwide cohort study of patients with prostate cancer in Sweden. Cancer Epidemiol. Biomarkers Prev. 13 12 (2004) 2203-2207
42. Malik I.A., Abbas Z., Shamsi Z., Daudi I., Shah H.A., Moid I., Khan Z.K., and Shaikh H. Immuno-histochemical analysis of estrogen receptors on the malignant gallbladder tissue. J. Pak. Med. Assoc. 48 5 (1998) 123-126
43. Maneesh Kumar D., Simpkins J.W., and Agarwal N. Estrogens and neuroprotection in retinal diseases. Mol. Vis. 14 (2008) 1480-1486
44. Marino M., Galluzzo P., and Ascenzi P. Estrogens signaling multiple pathways to impact gene transcription. Curr. Genomics. 7 8 (2006) 497-508
45. Marino M., Galluzzo P., Leone S., Acconcia F., and Ascenzi P. Nitric oxide impairs the 17beta-estradiol-induced apoptosis in human colon adenocarcinoma cells. Endocr. Relat. Cancer 13 2 (2006) 559-569
46. Martineti V., Picariello L., Tognarini I., Carbonell Sala S., Gozzini A., Azzari C., Mavilia C., Tanini A., Falchetti A., Fiorelli G., Tonelli F., and Brandi M.L. ERbeta is a potent inhibitor of cell proliferation in the HCT8 human colon cancer cell line through regulation of cell cycle components. Endocr. Relat. Cancer 12 2 (2005) 455-469
47. Matsui M., Kojima O., Uehara Y., and Takahashi T. Characterization of estrogen receptor in human gastric cancer. Cancer 15, 68 2 (1991) 305-308
48. Matsui M., Kojima O., Kawakami S., Uehara Y., and Takahashi T. The prognosis of patients with gastric cancer possessing sex hormone receptors. Surg. Today 22 5 (1992) 421-425
49. Matsuoka H., Sugimachi K., Ueo H., Kuwano H., Nakano S., and Nakayama M. Sex hormone response of a newly established squamous cell line derived from clinical esophageal carcinoma. Cancer Res. 1, 47 15 (1987) 4134-4140
50. Matsuoka H., Ueo H., Yano K., Kido Y., Shirabe K., Mitsudomi T., and Sugimachi K. Estradiol sensitivity test using contact-sensitive plates of confluent BALB/c 3T3 cell monolayers. Cancer Res. 1, 50 7 (1990) 2113-2118
51. Matsuyama S., Ohkura Y., Eguchi H., Kobayashi Y., Akagi K., Uchida K., Nakachi K., Gustafsson J.A., and Hayashi S. Estrogens receptor beta is expressed in human stomach adenocarcinoma. J. Cancer Res. Clin. Oncol. 128 6 (2002) 319-324
52. Moggs J.G., and Orphanides G. Estrogen receptors: orchestrators of pleiotropic cellular responses. EMBO Rep. 2 (2001) 775-781
53. Muchekehu R.W., and Harvey B.J. 17beta-estradiol rapidly mobilizes intracellular calcium from ryanodine-receptor-gated stores via a PKC-PKA-Erk-dependent pathway in the human eccrine sweat gland cell line NCL-SG3. Cell Calcium 44 3 (2008) 276-288
54. Nishi K., Tokunaga A., Shimizu Y., Yoshiyuki T., Wada M., Matsukura N., Tanaka N., Onda M., and Asano G. Immunohistochemical study of intracellular estradiol in human gastric cancer. Cancer 1, 59 7 (1987) 1328-1332
55. Park J.S., Jung W.H., Kim J.K., Hwang H.K., Cho S.I., Yoon D.S., Chi H.S., and Kim B.R. Estrogens receptor alpha, estrogens receptor beta, and progesterone receptor as possible prognostic factor in radically resected gallbladder carcinoma. J. Surg. Res. (2008) (Epub)
56. Pedram A., Razandi M., and Levin E.R. Nature of functional estrogen receptors at the plasma membrane. Mol. Endocrinol. 20 9 (2006) 1996-2009
57. Persson C., Inoue M., Sasazuki S., Kurahashi N., Iwasaki M., Ye W., Tsugane S., and JPHC Study Group. Female reproductive factors and the risk of gastric cancer in a large-scale population-based cohort study in Japan (JPHC study). Eur. J. Cancer Prev. 17 4 (2008) 345-353
58. Qiu Y., Waters C.E., Lewis A.E., Langman M.J., and Eggo M.C. Oestrogen-induced apoptosis in colonocytes expressing oestrogen receptor beta. J. Endocrinol. 174 3 (2002) 369-377
59. Ries L.A., Wingo P.A., Miller D.S., Howe H.L., Weir H.K., Rosenberg H.M., Vernon S.W., Cronin K., and Edwards B.K. The annual report to the nation on the status of cancer, 1973-1997, with a special section on colorectal cancer. Cancer 15, 88 10 (2000) 2398-2424
60. Ropero A.B., Fuentes E., Rovira J.M., Ripoll C., Soria B., and Nadal A. Non-genomic actions of 17beta-oestradiol in mouse pancreatic beta-cells are mediated by a cGMP-dependent protein kinase. J. Physiol. 1, 521 Pt 2 (1999) 397-407
61. Rossouw J.E., Anderson G.L., Prentice R.L., LaCroix A.Z., Kooperberg C., Stefanick M.L., Jackson R.D., Beresford S.A., Howard B.V., Johnson K.C., Kotchen J.M., Ockene J., and Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA 17, 288 3 (2002) 321-333
62. Sare G.M., Gray L.J., and Bath P.M. Association between hormone replacement therapy and subsequent arterial and venous vascular events: a meta-analysis. Eur. Heart J. 29 16 (2008) 2031-2041
63. Shirai T., Tsuda H., Ogiso T., Hirose M., and Ito N. Organ specific modifying potential of ethinyl estradiol on carcinogenesis initiated with different carcinogens. Carcinogenesis 8 1 (1987) 115-119
64. Sica V., Nola E., Contieri E., Bova R., Masucci M.T., Medici N., Petrillo A., Weisz A., Molinari A.M., and Puca G.A. Estradiol and progesterone receptors in malignant gastrointestinal tumors. Cancer Res. 44 10 (1984) 4670-4674
65. Simoncini T., and Genazzani A.R. Non-genomic actions of sex steroid hormones. Eur. J. Endocrinol. 148 (2003) 281-292
66. Simoncini T., Varone G., Fornari L., Mannella P., Luisi M., Labrie F., and Genazzani A.R. Genomic and nongenomic mechanisms of nitric oxide synthesis induction in human endothelial cells by a fourth-generation selective estrogen receptor modulator. Endocrinology 143 6 (2002) 2052-2061
67. Singh S., Poulsom R., Wright N.A., Sheppard M.C., and Langman M.J. Differential expression of oestrogen receptor and oestrogen inducible genes in gastric mucosa and cancer. Gut 40 4 (1997) 516-520
68. Sumi K., Matsuyama S., Kitajima Y., and Miyazaki K. Loss of estrogen receptor beta expression at cancer front correlates with tumor progression and poor prognosis of gallbladder cancer. Oncol. Rep. 12 5 (2004) 979-984
69. Suzuki F., Akahira J., Miura I., Suzuki T., Ito K., Hayashi S., Sasano H., and Yaegashi N. Loss of estrogen receptor beta isoform expression and its correlation with aberrant DNA methylation of the 5′-untranslated region in human epithelial ovarian carcinoma. Cancer Sci. 99 12 (2008) 2365-2372
70. Takano N., Iizuka N., Hazama S., Yoshino S., Tangoku A., and Oka M. Expression of estrogen receptor-alpha and -beta mRNAs in human gastric cancer. Cancer Lett. 25, 176 2 (2002) 129-135
71. Tian X.S., Zhou W.H., Wu G.J., Sun J.Z., and Cong M.H. Inhibitive effects of mifepristone on growth of breast cancer: experiment with rats. Zhonghua Yi Xue Za Zhi 26, 88 8 (2008) 559-563
72. Tiffin N., Suvarna S.K., Trudgill N.J., and Riley S.A. Sex hormone receptor immunohistochemistry staining in Barrett's oesophagus and adenocarcinoma. Histopathology 42 1 (2003) 95-96
73. Tokunaga A., Nishi K., Matsukura N., Tanaka N., Onda M., Shirota A., Asano G., and Hayashi K. Estrogen and progesterone receptors in gastric cancer. Cancer 1, 57 7 (1986) 1376-1379
74. Winborn W.B., Sheridan P.J., and McGill Jr. H.C. Autoradiographic demonstration of estrogen receptors in the esophagus. Gastroenterology 84 June (6) (1983) 1563-1567
75. Winter D.C., Taylor C., O'Sullivan C.G., and Harvey B.J. Mitogenic effects of oestrogen mediated by a non-genomic receptor in human colon. Br. J. Surg. 87 12 (2000) 1684-1689
76. Wu C.W., Tsay S.H., Chang T.J., Chang H.M., Hsieh M.C., Lui W.Y., P'eng F.K., and Chi C.W. Clinicopathologic comparisons between estrogen receptor-positive and -negative gastric cancers. J. Surg. Oncol. 51 4 (1992) 231-235
77. Wu C.W., Lui W.Y., P'eng F.K., and Chi C.W. Hormonal therapy for stomach cancer. Med. Hypotheses 39 2 (1992) 137-139
78. Xie L.Q., Yu J.P., and Luo H.S. Expression of estrogen receptor beta in human colorectal cancer. World J. Gastroenterol. 10 2 (2004) 214-217
79. Yokozaki H., Takekura N., Takanashi A., Tabuchi J., Haruta R., and Tahara E. Estrogens receptors in gastric adenocarcinoma: a retrospective immunohistochemical analysis. Virchows Arch. A Pathol. Anat. Histopathol. 413 4 (1988) 297-302
80. Yousef F., Cardwell C., Cantwell M.M., Galway K., Johnston B.T., and Murray L. The incidence of esophageal cancer and high-grade dysplasia in Barrett's esophagus: a systematic review and meta-analysis. Am. J. Epidemiol. 1, 168 3 (2008) 237-249
81. Zhao X.H., Gu S.Z., Liu S.X., and Pan B.R. Expression of estrogen receptor and estrogen receptor messenger RNA in gastric carcinoma tissues. World J. Gastroenterol. 9 4 (2003) 665-669