Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice

Bone

Volumn 45, Issue 1, 2009, Pages 98-103

  Gao, Qi ^a   Zhan, Peili ^a   Alander, Cynthia B ^a   Kream, Barbara E ^a   Hao, Chuanming ^b   Breyer, Matthew D ^b   Pilbeam, Carol C ^a   Raisz, Lawrence G ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Alkaline phosphatase; Differentiation; Osteoblast; Osteocalcin; Prostaglandin receptor

Indexed keywords

ALKALINE PHOSPHATASE; CRE RECOMBINASE; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; OSTEOCALCIN; PROSTAGLANDIN E EP4 RECEPTOR; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; BODY WEIGHT; BONE DENSITY; BONE REMODELING; C57BL 6 MOUSE; CALCIUM BLOOD LEVEL; CALVARIA; CELL CULTURE; CELL DIFFERENTIATION; CELL LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME ACTIVITY; FEMALE; GENE DELETION; GENETIC RECOMBINATION; GENOTYPE; HETEROZYGOTE; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PARATHYROID HORMONE BLOOD LEVEL; PROMOTER REGION; PROTEIN EXPRESSION; WEANING; WILD TYPE;

AGING; ANIMALS; BODY COMPOSITION; BONE AND BONES; BREEDING; CELLS, CULTURED; DINOPROSTONE; FEMALE; GENE DELETION; GENOTYPE; HETEROZYGOTE; MALE; MICE; NITROBENZENES; OSTEOBLASTS; RECEPTORS, PROSTAGLANDIN E; SULFONAMIDES; SURVIVAL RATE; WEANING;

EID: 67349270945     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.03.667     Document Type: Article

References (22)

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