Rearrangement of a conditional allele regardless of inheritance of a Cre recombinase transgene

Genesis (United States)

Volumn 45, Issue 1, 2007, Pages 17-20

  Cochrane, Rebecca L ^a   Clark, Stephen H ^a   Harris, Adam ^a   Kream, Barbara E ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Col1a1 promoter; Conditional knockout; Cre loxP; lgf1; Osteoblast

Indexed keywords

CRE RECOMBINASE;

ALLELISM; ANIMAL EXPERIMENT; ARTICLE; COL1A1 GENE; DNA FLANKING REGION; EXON; GENE; GENE LOCUS; GENE REARRANGEMENT; IGF1 GENE; INHERITANCE; LOXP SITE; MOLECULAR CLONING; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; TRANSGENE; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS; RATTUS;

EID: 33846847803     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.20259     Document Type: Article

References (17)

1. Dacic S, Kalajzic I, Visnjic D, Lichtler AC, Rowe DW. 2001. Col1a1-driven transgenic markers of osteoblast lineage progression. J Bone Miner Res 16:1228-1236.
2. Hayashi S, Tenzen T, McMahon AP. 2003. Maternal inheritance of Cre activity in a Sox2Cre deleter strain. Genesis 37:51-53.
3. He Z, Feng L, Zhang X, Geng Y, Parodi DA, Suarez-Quian C, Dym M. 2005. Expression of Col1a1, Col1a2, and procollagen I in germ cells of immature and adult mouse testis. Reproduction 130:333-341.
4. Kalajzic Z, Liu P, Kalajzic I, Du Z, Braut A, Mina M, Canalis E, Rowe DW. 2002. Directing the expression of a green fluorescent protein transgene in differentiated osteoblasts: Comparison between rat type I collagen and rat osteocalcin promoters. Bone 31:654-660.
5. Liu F, Woitge HW, Braut A, Kronenberg MS, Lichtler AC, Mina M, Kream BE. 2004. Expression and activity of osteoblast-targeted Cre recombinase transgenes in murine skeletal tissues. Int J Dev Biol 48:645-653.
6. Liu JL, Grinberg A, Westphal H, Sauer B, Accili D, Karas M, LeRoith D. 1998. Insulin-like growth factor-I affects perinatal lethality and postnatal development in a gene dosage-dependent manner: Manipulation using the Cre/loxP system in transgenic mice. Mol Endocrinol 12:1452-1462.
7. Liu JL, Yakar S, LeRoith D. 2000. Conditional knockout of mouse insulin-like growth factor-1 gene using the Cre/loxP system. Proc Soc Exp Biol Med 223:344-351.
8. Nagy A. 2000. Cre recombinase: The universal reagent for genome tailoring. Genesis 26:99-109.
9. Powell-Braxton L, Hollingshead P, Giltinan D, Pitts-Meek S, Stewart T. 1993a. Inactivation of the IGF-I gene in mice results in perinatal lethality. Ann NYAcad Sci 692:300-301.
10. Powell-Braxton L, Hollingshead P, Warburton C, Dowd M, Pitts-Meek S, Dalton D, Gillett N, Stewart TA. 1993b. IGF-I is required for normal embryonic growth in mice. Genes Dev 7:2609-2617.
11. Ramirez A, Page A, Gandarillas A, Zanet J, Pibre S, Vidal M, Tusell L, Genesca A, Whitaker DA, Melton DW, Jorcano JL. 2004. A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination. Genesis 39:52-57.
12. Sakai K, Miyazaki J. 1997. A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission. Biochem Biophys Res Commun 237:318-324.
13. Soriano P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21:70-71.
14. Vidal F, Sage J, Cuzin F, Rassoulzadegan M. 1998. Cre expression in primary spermatocytes: A tool for genetic engineering of the germ line. Mol Reprod Dev 51:274-280.
15. Vincent SD, Robertson EJ. 2003. Highly efficient transgene-independent recombination directed by a maternally derived SOX2CRE transgene. Genesis 37:54-56.
16. Yakar S, Liu JL, Stannard B, Butler A, Accili D, Sauer B, LeRoith D. 1999. Normal growth and development in the absence of hepatic insulin-like growth factor I. Proc Natl Acad Sci USA 96:7324-7329.
17. Zhang M, Xuan S, Bouxsein ML, von Stechow D, Akeno N, Faugere MC, Malluche H, Zhao G, Rosen CJ, Efstratiadis A, Clemens TL. 2002. Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization. J Biol Chem 277:44005-44012.