Impact of radiotherapy and chemotherapy on biomarkers of oxidative DNA damage in lung cancer patients

Clinical Biochemistry

Volumn 42, Issue 10-11, 2009, Pages 1082-1090

  Crohns, Marika ^a,b   Saarelainen, Seppo ^a,c   Erhola, Marina ^d   Alho, Hannu ^e,f   Kellokumpu Lehtinen, Pirkko ^a,c  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b PIRKANMAA HOSPITAL DISTRICT   (Finland)

^c TAMPERE UNIVERSITY HOSPITAL   (Finland)

^d The Municipal Joint Union For Public Health in the Hämeenlinna Region ^*  (Finland)

^e NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^f HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

8 oxodG; 8 oxoGua; Chemotherapy; Lung cancer; Oxidative DNA damage; Radiotherapy

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8 HYDROXYGUANINE; BIOLOGICAL MARKER; CYCLOPHOSPHAMIDE; DNA; DOXORUBICIN; VINCRISTINE;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CANCER RADIOTHERAPY; CANCER STAGING; CONTROLLED STUDY; DNA DAMAGE; FEMALE; HUMAN; LINEAR ACCELERATOR; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; OXIDATIVE STRESS; PRIORITY JOURNAL; TREATMENT DURATION; TREATMENT OUTCOME; URINALYSIS;

AGED; AGED, 80 AND OVER; DEMOGRAPHY; DEOXYGUANOSINE; DNA DAMAGE; FEMALE; GUANINE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; OXIDATIVE STRESS; SURVIVAL ANALYSIS; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 67349267787     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2009.02.022     Document Type: Article

References (48)

1. Riley P.A. Free radicals in biology: oxidative stress and the effects of ionizing radiation. Int. J. Radiat. Biol. 65 (1994) 27-33
2. Olinski R., Gackowski D., Foksinski M., Rozalski R., Roszkowski K., and Jaruga P. Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome. Free Radic. Biol. Med. 33 (2002) 192-200
3. Siomek A., Tujakowski J., Gackowki D., et al. Severe oxidatively damaged DNA after cisplatin treatment of cancer patients. Int. J. Cancer 119 (2006) 2228-2230
4. Chiou C.C., Chang P.Y., Chan E.C., Wu T.L., Tsao K.C., and Wu J.T. Urinary 8-hydroxydeoxyguanosine and its analogs as DNA marker of oxidative stress: development of an ELISA and measurement in both bladder and prostate cancers. Clin. Chim. Acta 334 (2003) 87-94
5. th edition (2007), Oxford University Press, Oxford, UK
6. Faure H., Mousseau M., Cadet J., et al. Urine 8-oxo-7,8-dihydro-2-deoxyguanosine vs. 5-(hydroxymethyl) uracil as DNA oxidation marker in adriamycin- treated patients. Free Radic. Res. 28 (1998) 377-382
7. Erhola M., Toyokuni S., Okada K., et al. Biomarker evidence of DNA oxidation in lung cancer patients: association of urinary 8-hydroxy-2′-deoxyguanosine excretion with radiotherapy, chemotherapy, and response to treatment. FEBS Lett. 409 (1997) 287-291
8. Rozalski R., Gackowski D., Roszkowski K., Foksinski M., and Olinski R. The level of 8-hydroxyguanine, a possible repair product of oxidative DNA damage, is higher in urine of cancer patients than in control subjects. Cancer Epidemiol. Biomarkers. Prev. 11 (2002) 1072-1075
9. Yamamoto T., Hosokawa K., Tamura T., Kanno H., Urabe M., and Honjo H. Urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG) levels in women with or without gynecologic cancer. J. Obstet. Gynaecol. Res. 22 (1996) 359-363
10. Mei S., Yao Q., Wu C., and Xu G. Determination of urinary 8-hydroxy-2′-deoxyguanosine by two approaches-capillary electrophoresis and GC/MS: an assay for in vivo oxidative DNA damage in cancer patients. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 827 (2005) 83-87
11. Miyake H., Hara I., Kamidono S., and Eto H. Oxidative DNA damage in patients with prostate cancer and its response to treatment. J. Urol. 171 (2004) 1533-1536
12. Tagesson C., Källberg M., Klintenberg C., and Starkhammar H. Determination of urinary 8-hydroxydeoxyguanosine by automated coupled-column high performance liquid chromatography: a powerful technique for assaying in vivo oxidative DNA damage in cancer patients. Eur. J. Cancer 31 (1995) 934-940
13. Yamazaki H., Inoue T., Koizumi M., et al. Urinary 8-hydroxy-2′-deoxyguanosine excretion as a biomarker for estimating DNA oxidation in patients undergoing external radiotherapy and/or brachytherapy. Oncol. Rep. 13 (2005) 847-851
14. Honda M., Yamada Y., Tomonaga M., Ichinose H., and Kamihira S. Correlation of urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG), a biomarker of oxidative DNA damage, and clinical features of hematological disorders: a pilot study. Leuk. Res. 24 (2000) 461-468
15. Haghdoost S., Svoboda P., Näslund I., Harms-Ringdahl M., Tilikides A., and Skog S. Can 8-oxo-dG be used as a predictor for individual radiosensitivity?. Int. J. Radiat. Oncol. Biol. Phys. 50 (2001) 405-410
16. In: Sobin L.H., and Wittekind C.H. (Eds). International Union Against Cancer. TNM Classification of Malignant Tumors. 5th ed. (1996), Wiley-Liss, New York, NY, USA
17. Schiller J.H. Current standards of care in small-cell and non-small-cell lung cancer. Oncology 61 (2001) 3-13
18. The Alpha-Tocopherol. Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta-carotene on the incidence of lung cancer and other cancers in male smokers. New Engl. J. Med. 330 (1994) 1029-1035
19. Gackowski D., Rozalski R., Roszkowski K., Jawien A., Foksinski M., and Olinski R. 8-Oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2′-deoxyguanosine levels in human urine do not depend on diet. Free Radic. Res. 35 (2001) 825-832
20. Gackowski D., Speina E., Zielinska M., et al. Products of oxidative DNA damage and repair as possible biomarkers of susceptibility to lung cancer. Cancer Res. 63 (2003) 4899-4902
21. Dizdaroglu M. Chemical determination of oxidative DNA damage by gas chromatography-mass spectrometry. Methods Enzymol. 234 (1994) 3-16
22. Lahiri D.K., and Nurnberger Jr. J.I. A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucl. Acids. Res. 19 (1991) 5444
23. Helbock H.J., Beckman K.B., Shigenaga M.K., et al. DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine. Proc. Natl. Acad. Sci. USA 95 (1998) 288-293
24. Shigenaga M.K., Gimeno C.J., and Ames B.N. Urinary 8-hydroxy-2′-deoxyguanosine as a biological marker of in vivo oxidative DNA damage. Proc. Natl. Acad. Sci. USA 86 (1989) 9697-9701
25. Miller A.B., Hoogstraten B., Staquet M., and Winkler A. Reporting results of cancer treatment. Cancer 47 (1981) 207-214
26. LENT SOMA tables. Radiother. Oncol. 35 (1995) 17-60
27. World Health Organization: WHO Handbook for Reporting Results of Cancer Treatment, Geneva, Switzerland: WHO Offset Publication No 48;1979.
28. Bland J.M., and Altman D.G. Calculating correlation coefficients with repeated observations: part 1-correlation within subjects. BMJ 310 (1995) 446
29. Cooke M.S., Evans M.D., Dizdaroglu M., and Lunec J. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J. 17 (2003) 1195-1214
30. Wu L.L., Chiou C.C., Chang P.Y., and Wu J.T. Urinary 8-OHdG: a marker of oxidative stress to DNA and a risk factor for cancer, atherosclerosis and diabetics. Clin. Chim. Acta 339 (2004) 1-9
31. Loft S., Svoboda P., Kasai H., et al. Prospective study of 8-oxo-7,8-dihydro-2′-deoxyguanosine excretion and the risk of lung cancer. Carcinogenesis 27 (2006) 1245-1250
32. Poulsen H.E., Loft S., and Vistisen K. Extreme exercise and oxidative DNA modification. J. Sports Sci. 14 (1996) 343-346
33. Loft S., Vistisen K., Ewertz M., Tjønneland A., Overvad K., and Poulsen H.E. Oxidative DNA damage estimated by 8-hydroxydeoxyguanosine excretion in humans: influence of smoking, gender and body mass index. Carcinogenesis 13 (1992) 2241-2247
34. Foksinski M., Gackowski D., Rozalski R., et al. Effects of basal level of antioxidants on oxidative DNA damage in humans. Eur J Nutr 46 (2007) 174-180
35. Lodovici M., Caldini S., Luceri C., Bambi F., Boddi V., and Dolara P. Active and passive smoking and lifestyle determinants of 8-oxo-7,8-dihydro-2′-deoxyguanosine levels in human leukocyte DNA. Cancer Epidemiol Biomarkers Prev 14 (2005) 2975-2977
36. Gackowski D., Kowalewski J., Siomek A., and Olinski R. Oxidative DNA damage and antioxidant vitamin level: comparison among lung cancer patients, healthy smokers and nonsmokers. Int. J. Cancer 114 (2005) 153-156
37. Vulimiri S.V., Wu X., Baer-Dubowska W., et al. Analysis of aromatic DNA adducts and 7,8-dihydro-8-oxo-2′ deoxyguanosine in lymphocyte DNA from a case-control study of lung cancer involving minority populations. Mol. Carcinogenesis 27 (2000) 34-46
38. Malayappan B., Garrett T.J., Segal M., and Leeuwenburgh C. Urinary analysis of 8-oxoguanine, 8-oxoguanosine, fapy-guanine and 8-oxo-2′-deoxyguanosine by high-performance liquid chromatography-electrospray tandem mass spectrometry as a measure of oxidative stress. J. Chromatogr. A. 1167 (2007) 54-62
39. Speina E., Arczewska K.D., Gackowski D., et al. Contribution of hMTH1 to the maintenance of 8-oxoguaninen levels in lung DNA of non-small-cell lung cancer patients. J Natl Cancer Inst 97 (2005) 384-395
40. Wu H.C., Wang Q., Wang L.W., et al. Urinary 8-oxodeoxyguanosine, aflatoxin B1 exposure and hepatitis B virus infection and hepatocellular carcinoma in Taiwan. Carcinogenesis 28 (2007) 995-999
41. Pilger A., Germadnik D., Schaffer A., et al. 8-Hydroxydeoxyguanosine in leukocyte DNA and urine of quartz-exposed workers and patients with silicosis. Int. Arch. Occup. Environ. Health 73 (2000) 305-310
42. Tagesson C., Källberg M., and Wingren G. Urinary malondialdehyde and 8-hydroxydeoxyguanosine as potential markers of oxidative stress in industrial art glass workers. Int. Arch. Occup. Environ. Health 69 (1996) 5-13
43. Rozalski R., Siomek A., Gackowski D., et al. Diet is not responsible for the presence of several oxidatively damaged DNA lesions in mouse urine. Free Radic. Res. 38 (2004) 1201-1205
44. Gedik C.M., Boyle S.P., Wood S.G., Vaughan N.J., and Collins A.R. Oxidative stress in humans: validation of biomarkers of DNA damage. Carcinogenesis 23 (2002) 1441-1446
45. Bergman V., Leanderson P., Starkhammar H., and Tagesson C. Urinary excretion of 8-hydroxydeoxyguanosine and malondialdehyde after high dose radiochemotherapy preceding stem cell transplantation. Free Radic. Biol. Med. 3 (2004) 300-306
46. Bialkowski K., Kowara R., Windorbska W., and Olinski R. 8-Oxo-2′-deoxyguanosine level in lymphocytes DNA of cancer patients undergoing radiotherapy. Cancer Lett. 99 (1996) 93-97
47. Zwingmann I.H., Welle I.J., Engelen J.J., Schilderman P.A., de Jong J.M., and Kleinjans J.C. Analysis of oxidative DNA damage and HPRT mutant frequencies in cancer patients before and after radiotherapy. Mutat. Res. 431 (1999) 361-369
48. Mousseau M., Faure H., Hininger I., Bayet-Robert M., and Favier A. Leukocyte 8-oxo-7,8-dihydro-2′-deoxyguanosine and comet assay in epirubicin-treated patients. Free Radic. Res. 39 (2005) 837-843