Analysis of oxidative DNA damage and HPRT mutant frequencies in cancer patients before and after radiotherapy

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 431, Issue 2, 1999, Pages 361-369

  Zwingmann, Ivo H ^a   Welle, Irene J ^a   Engelen, John J M ^a   Schilderman, Pauline A E L ^a   De Jong, Jos M A ^b   Kleinjans, Jos C S ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRO CLINIC   (Netherlands)

Author keywords

HPRT mutant frequency; Micronuclei; Oxidative DNA damage; Radiotherapy

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER RADIOTHERAPY; CLINICAL ARTICLE; DNA DAMAGE; DNA DETERMINATION; FEMALE; GENE MUTATION; GENOTOXICITY; HEAD AND NECK CANCER; HUMAN; MALE; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION INJURY;

AGED; AGED, 80 AND OVER; ANTIOXIDANTS; BIOLOGICAL MARKERS; BREAST NEOPLASMS; BROMODEOXYURIDINE; DEOXYGUANOSINE; DNA DAMAGE; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MALE; MICRONUCLEUS TESTS; MIDDLE AGED; NEOPLASMS; OXIDATION-REDUCTION; PROSTATIC NEOPLASMS; SMOKING;

EID: 0033397451     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(99)00179-7     Document Type: Article

References (40)

1. Evans H.J., O'Riordan M.L. Human peripheral blood lymphocytes for the analysis of chromosome aberrations in mutagen tests. Mutat. Res. 31:1975;135-148.
2. Fenech M., Morley A.A. Measurement of micronuclei in lymphocytes. Mutat. Res. 147:1985;29-36.
3. Livingston G.K., Foster A.E., Elson H.R. Effect of in vivo exposure to iodine-131 on the frequency and persistence of micronuclei in human lymphocytes. J. Toxicol. Environ. Health. 40:1993;367-375.
4. Lazutka R., Dedonyte V. Increased frequency of sister chromatid exchanges in lymphocytes of Chernobyl clean-up workers. Int. J. Rad. Biol. 67:1995;671-676.
5. Sardas S., Erdogan F., Sardas O.S., Cengel M., Karakaya A.E. Sister chromatid exchange studies for monitoring DNA damage in lymphocytes of malignant lymphoma patients under cytostatic therapy. Anticancer Drugs. 5:1994;487-489.
6. Kyoizumi S., Nakamura N., Hadoka M., Awa A.A., Bean M.A., Jensen R.H., Akiyama M. Detection of somatic mutations at the glycophorin A locus of erythrocytes of atomic bomb survivors using single beam flow sorter. Cancer Res. 49:1989;581-588.
7. Akiyama M., Kyoizumi S., Kusunoki Y., Hirai Y., Tanabe K., Cologne J.B. Monitoring exposure to atomic bomb radiation by somatic mutation. Environ. Health Perspect. 104:1996;493-496.
8. Langlois R.G., Akiyama M., Kusunoki Y., Dupont B.R., Moore D.H., Bigbee W.L., Grant S.G., Jensen R.H. Analysis of somatic cell mutations at the glycophorin A locus in atomic bomb survivors: a comparative study of assay methods. Radiat. Res. 136:1993;111-117.
9. Seifert A.M., Bradley W.E.C., Messing K. Exposure of nuclear medicine patients to ionizing radiation is associated with rises in HPRT mutant frequency in peripheral T-lymphocytes. Mutat. Res. 191:1987;57-63.
10. Nicklas J.A., O'Neill J.P., Hunter T.C., Falta M.T., Lippert M.J., Jacobson-Kram D., Williams J.R., Albertini R.J. In vivo ionizing irradiations produce deletions in the hprt gene of human T-lymphocytes. Mutat. Res. 250:1991;383-396.
11. Albertini R.J., Nicklas J.A., Fuscoe J.C., Skopek T.R., Branda R.F., O'Neill J.P. In vivo mutations in human blood cells: biomarkers for molecular epidemiology. Environ. Health Perspect. 99:1993;135-141.
12. Albering H.J., Engelen J.J., Koulischer L., Welle I.J., Kleinjans J.C. Indoor radon, an extrapulmonary genetic risk? The Lancet. 244:1994;750-751.
13. Janatipour M., Trainor K.J., Kutlaca R., Benett G., Hay J., Turner D.R., Morley A.A. Mutations in human lymphocytes studied by the HLA selection system. Mutat. Res. 198:1988;221-226.
14. Bender M.A., Awa A.A., Brooks A.L., Evans H.J., Groer P.G., Littlefield L.G., Pereira C., Preston R.J., Wachholz B.W. Current status of cytogenetic procedures to detect and quantify previous exposures to radiation. Mutat. Res. 196:1988;103-159.
15. Fenech M.F., Dunaiski V., Osborne Y., Morley A.A. The cytokinesis-block micronucleus assay as a biological dosimeter in spleen and peripheral blood lymphocytes of the mouse following acute whole-body irradiation. Mutat. Res. 263:1991;119-126.
16. Lee T-K., Wiley A.L. Jr., Esinhart J.D., Blackburn L.D. Radiation dose-dependent variations of micronuclei production in cytochalasin B-blocked human lymphocytes. Teratogen. Carcinogen. Mutagen. 14:1994;1-12.
17. Wilson V.L., Taffe B.G., Shields P.G., Povey A.C., Harris C.C. Detection and quantification of 8-hydroxydeoxyguanosine adducts in peripheral blood of people exposed to ionising radiation. Environ. Health Perspect. 99:1993;261-263.
18. Bialkowski K., Kowara R., Windorbska W., Olinski R. 8-oxo-2′-deoxyguanosine in lymphocytes DNA of cancer patients undergoing radiotherapy. Cancer Lett. 99:1996;93-97.
19. Olinski R., Zastawny T.H., Foksinski M., Windorbska W., Jaruga P., Dizdaroglu M. DNA base damage in lymphocytes of cancer patients undergoing radiation therapy. Cancer Lett. 106:1996;207-215.
20. Collins A.R., Dusinska M., Gedik C.M., Stetina R. Oxidative damage to DNA: Do we have a reliable marker? Environ. Health Perspect. 104:1996;465-469.
21. Floyd R.A. The role of 8-hydroxyguanosine in carcinogenesis. Carcinogenesis. 11:1990;1447-1450.
22. Thilly W.G., Deluca J.G., Hoppe H.I.V., Pennman B.W. Phenotypic lag and mutation to 6-thioguanine resistant in diploid human lymphoblasts. Mutat. Res. 50:1978;137-144.
23. Schilderman P.A.E.L., van Maanen J.M.S., ten Vaarwerk F.J., Lafleur M.V.M., Westmijze E.J., ten Hoor F., Kleinjans J.C.S. The role of prostaglandin H synthase-mediated metabolism in the induction of oxidative DNA damage by BHA metabolites. Carcinogenesis. 14:1993;1297-1302.
24. Gupta R.C. Non-random binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo. Proc. Natl. Acad. Sci. U.S.A. 81:1984;9634-9647.
25. Miller N.J., Rice-evans C., Davies M.J., Gopinathan V., Milner A. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin. Sci. 84:1993;407-412.
26. Rice-Evans C., Miller N.J. Total antioxidant status in plasma and body fluids. Methods Enzymol. 234:1994;279-293.
27. Countryman P.I., Heddle J.A. The production of micronuclei from chromosomal aberration in irradiated cultures of human lymphocytes. Mutat. Res. 41:1976;321-332.
28. Hageman G., Welle I., Stierum R., Albering H., Kleinjans J. Detection of 6-thioguanine-resistant human blood lymphocytes using 5-bromodeoxyuridine labeling in combination with immunocytochemical staining. Mutagenesis. 8:1993;495-501.
29. Fischer-Nielsen A., Bogh Jeding I., Loft S. Radiation-induced formation of 8-hydroxy-2′-deoxyguanosine and its prevention by scavengers. Carcinogenesis. 15:1994;1609-1612.
30. 33P-postlabeling and electrochemical detection. Carcinogenesis. 18:1997;2367-2371.
31. Plappert U.G., Stocker B., Fender H., Fliedner T.M. Changes in repair capacity of blood cells as a biomarker for chronic low-dose exposure to ionizing radiation. Environ. Mol. Mutagen. 30:1997;153-160.
32. Rigaud O., Guedeney G., Duranton I., Leroy A., Doloy M.T., Magdelenat H. Genotoxic effects of radiotherapy and chemotherapy on the circulating lymphocytes of breast cancer patients: II. Alteration of DNA repair and chromosome radiosensititvity. Mutat. Res. 242:1990;25-35.
33. Asami S., Manabe H., Miyake J., Tsurudome Y., Hirano T., Yamaguchi R., Itoh H., Kasai H. Cigarette smoking induces an increase in oxidative DNA damage, 8-hydroxydeoxyguanosine, in a central site of the human lung. Carcinogenesis. 18:1997;1763-1766.
34. Montero R., Gonsebatt M.E., Herrera L.A., Rojas E., Ostrosky-Wegman P. The HPRT short-term assay in monitoring individuals exposed to genotoxic agents. Environ. Health Perspect. 101(Suppl. 3):1993;135-138.
35. Ammenheuser M.M., Hastings D.A., Whorton E.B. Jr., Ward J.B. Jr. Frequencies of hprt mutant lymphocytes in smokers, non-smokers, and former smokers. Environ. Mol. Mutagen. 30:1997;131-138.
36. Ammenheuser M.M., Au W.W., Whorton E.B. Jr., Belli J.A., Ward J. Jr. Comparison of hprt variant frequencies and chromosome aberration frequencies in lymphocytes from radiotherapy and chemotherapy patients: a prospective study. Environ. Mol. Mutagen. 18:1991;126-135.
37. Caggana M., Kelsey K.T. Sister chromatid exchange frequency in Hodgkin's disease patients with elevated in vivo hprt mutant frequencies. Carcinogenesis. 12:1991;2141-2145.
38. Tates A.D., van Dam F.J., Natarajan A.T., Zwinderman A.H., Osanta S. Frequencies of HPRT mutants and micronuclei in lymphocytes of cancer patients under chemotherapy: a prospective study. Mutat. Res. 307:1994;293-306.
39. Fenech M., Denham J., Francis W., Morley A. Micronuclei in cytokinesis-blocked lymphocytes of cancer patients following fractionated partial-body radiotherapy. Int. J. Radiat. Biol. 57:1990;373-383.
40. Thierens H., Vral A., van Eijkeren M., Speleman F., de Ridder L. Micronucleus induction in peripheral blood lymphocytes of patients under radiotherapy treatment for cervical cancer or Hodgkin's disease. Int. J. Radiat. Biol. 67:1995;529-539.