메뉴 건너뛰기




Volumn 91, Issue 6, 2009, Pages 2664-2675

Expression of insulin-like growth factors (IGFs) and IGF signaling: molecular complexity in uterine leiomyomas

Author keywords

IGF pathway; IGF 1; IGF 2; leiomyomas; promoter; tissue microarray

Indexed keywords

DNA; MESSENGER RNA; PROTEIN KINASE B; S6 KINASE; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN C; TUBERIN;

EID: 67349265981     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2007.10.083     Document Type: Article
Times cited : (49)

References (46)
  • 1
    • 0037245894 scopus 로고    scopus 로고
    • High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence
    • Day Baird D., Dunson D.B., Hill M.C., Cousins D., and Schectman J.M. High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence. Am J Obstet Gynecol 188 (2003) 100-107
    • (2003) Am J Obstet Gynecol , vol.188 , pp. 100-107
    • Day Baird, D.1    Dunson, D.B.2    Hill, M.C.3    Cousins, D.4    Schectman, J.M.5
  • 5
    • 18744410984 scopus 로고    scopus 로고
    • Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review
    • Arslan A.A., Gold L.I., Mittal K., Suen T.C., Belitskaya-Levy I., Tang M.S., et al. Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review. Hum Reprod 20 (2005) 852-863
    • (2005) Hum Reprod , vol.20 , pp. 852-863
    • Arslan, A.A.1    Gold, L.I.2    Mittal, K.3    Suen, T.C.4    Belitskaya-Levy, I.5    Tang, M.S.6
  • 6
    • 0033675860 scopus 로고    scopus 로고
    • Immunohistochemical localization of growth factors and their receptors in uterine leiomyomas and matched myometrium
    • Dixon D., He H., and Haseman J.K. Immunohistochemical localization of growth factors and their receptors in uterine leiomyomas and matched myometrium. Environ Health Perspect 108 Suppl 5 (2000) 795-802
    • (2000) Environ Health Perspect , vol.108 , Issue.SUPPL. 5 , pp. 795-802
    • Dixon, D.1    He, H.2    Haseman, J.K.3
  • 8
    • 0027515736 scopus 로고
    • Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata
    • Giudice L.C., Irwin J.C., Dsupin B.A., Pannier E.M., Jin I.H., Vu T.H., et al. Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata. Hum Reprod 8 (1993) 1796-1806
    • (1993) Hum Reprod , vol.8 , pp. 1796-1806
    • Giudice, L.C.1    Irwin, J.C.2    Dsupin, B.A.3    Pannier, E.M.4    Jin, I.H.5    Vu, T.H.6
  • 10
    • 0033808363 scopus 로고    scopus 로고
    • Gene expression and tissue concentrations of IGF-I in human myometrium and fibroids under different hormonal conditions
    • Englund K., Lindblom B., Carlstrom K., Gustavsson I., Sjoblom P., and Blanck A. Gene expression and tissue concentrations of IGF-I in human myometrium and fibroids under different hormonal conditions. Mol Hum Reprod 6 (2000) 915-920
    • (2000) Mol Hum Reprod , vol.6 , pp. 915-920
    • Englund, K.1    Lindblom, B.2    Carlstrom, K.3    Gustavsson, I.4    Sjoblom, P.5    Blanck, A.6
  • 12
    • 0035180145 scopus 로고    scopus 로고
    • Up-regulation by IGF-I of proliferating cell nuclear antigen and Bcl-2 protein expression in human uterine leiomyoma cells
    • Gao Z., Matsuo H., Wang Y., Nakago S., and Maruo T. Up-regulation by IGF-I of proliferating cell nuclear antigen and Bcl-2 protein expression in human uterine leiomyoma cells. J Clin Endocrinol Metab 86 (2001) 5593-5599
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5593-5599
    • Gao, Z.1    Matsuo, H.2    Wang, Y.3    Nakago, S.4    Maruo, T.5
  • 14
    • 0025077575 scopus 로고
    • Expression of the insulin-like and platelet-derived growth factor genes in human uterine tissues
    • Boehm K.D., Daimon M., Gorodeski I.G., Sheean L.A., Utian W.H., and Ilan J. Expression of the insulin-like and platelet-derived growth factor genes in human uterine tissues. Mol Reprod Dev 27 (1990) 93-101
    • (1990) Mol Reprod Dev , vol.27 , pp. 93-101
    • Boehm, K.D.1    Daimon, M.2    Gorodeski, I.G.3    Sheean, L.A.4    Utian, W.H.5    Ilan, J.6
  • 15
    • 0037717021 scopus 로고    scopus 로고
    • Differential gene expression in uterine leiomyoma
    • Skubitz K.M., and Skubitz A.P. Differential gene expression in uterine leiomyoma. J Lab Clin Med 141 (2003) 297-308
    • (2003) J Lab Clin Med , vol.141 , pp. 297-308
    • Skubitz, K.M.1    Skubitz, A.P.2
  • 16
    • 1242314757 scopus 로고    scopus 로고
    • Targeted cellular process profiling approach for uterine leiomyoma using cDNA microarray, proteomics and gene ontology analysis
    • Ahn W.S., Kim K.W., Bae S.M., Yoon J.H., Lee J.M., Namkoong S.E., et al. Targeted cellular process profiling approach for uterine leiomyoma using cDNA microarray, proteomics and gene ontology analysis. Int J Exp Pathol 84 (2003) 267-279
    • (2003) Int J Exp Pathol , vol.84 , pp. 267-279
    • Ahn, W.S.1    Kim, K.W.2    Bae, S.M.3    Yoon, J.H.4    Lee, J.M.5    Namkoong, S.E.6
  • 17
    • 0042855701 scopus 로고    scopus 로고
    • Distinctive proliferative phase differences in gene expression in human myometrium and leiomyomata
    • Wang H., Mahadevappa M., Yamamoto K., Wen Y., Chen B., Warrington J.A., et al. Distinctive proliferative phase differences in gene expression in human myometrium and leiomyomata. Fertil Steril 80 (2003) 266-276
    • (2003) Fertil Steril , vol.80 , pp. 266-276
    • Wang, H.1    Mahadevappa, M.2    Yamamoto, K.3    Wen, Y.4    Chen, B.5    Warrington, J.A.6
  • 18
    • 0042354626 scopus 로고    scopus 로고
    • Strategy for elucidating differentially expressed genes in leiomyomata identified by microarray technology
    • Catherino W.H., Prupas C., Tsibris J.C., Leppert P.C., Payson M., Nieman L.K., et al. Strategy for elucidating differentially expressed genes in leiomyomata identified by microarray technology. Fertil Steril 80 (2003) 282-290
    • (2003) Fertil Steril , vol.80 , pp. 282-290
    • Catherino, W.H.1    Prupas, C.2    Tsibris, J.C.3    Leppert, P.C.4    Payson, M.5    Nieman, L.K.6
  • 19
    • 0036295999 scopus 로고    scopus 로고
    • Insights from gene arrays on the development and growth regulation of uterine leiomyomata
    • Tsibris J.C., Segars J., Coppola D., Mane S., Wilbanks G.D., O'Brien W.F., et al. Insights from gene arrays on the development and growth regulation of uterine leiomyomata. Fertil Steril 78 (2002) 114-121
    • (2002) Fertil Steril , vol.78 , pp. 114-121
    • Tsibris, J.C.1    Segars, J.2    Coppola, D.3    Mane, S.4    Wilbanks, G.D.5    O'Brien, W.F.6
  • 21
    • 4544307523 scopus 로고    scopus 로고
    • Molecular characterization of uterine fibroids and its implication for underlying mechanisms of pathogenesis
    • Hoffman P.J., Milliken D.B., Gregg L.C., Davis R.R., and Gregg J.P. Molecular characterization of uterine fibroids and its implication for underlying mechanisms of pathogenesis. Fertil Steril 82 (2004) 639-649
    • (2004) Fertil Steril , vol.82 , pp. 639-649
    • Hoffman, P.J.1    Milliken, D.B.2    Gregg, L.C.3    Davis, R.R.4    Gregg, J.P.5
  • 22
    • 0029039059 scopus 로고
    • Insulin-like growth factor II in uterine smooth-muscle tumors: maintenance of genomic imprinting in leiomyomata and loss of imprinting in leiomyosarcomata
    • Vu T.H., Yballe C., Boonyanit S., and Hoffman A.R. Insulin-like growth factor II in uterine smooth-muscle tumors: maintenance of genomic imprinting in leiomyomata and loss of imprinting in leiomyosarcomata. J Clin Endocrinol Metab 80 (1995) 1670-1676
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 1670-1676
    • Vu, T.H.1    Yballe, C.2    Boonyanit, S.3    Hoffman, A.R.4
  • 23
    • 13344279400 scopus 로고    scopus 로고
    • Maintenance of imprinting of the insulin-like growth factor II gene (IGF2) and the small nuclear ribonucleoprotein polypeptide N gene (SNRPN) in the human uterus and leiomyoma
    • Hashimoto K., Azuma C., Kamiura S., Koyama M., Nobunaga T., Tokugawa Y., et al. Maintenance of imprinting of the insulin-like growth factor II gene (IGF2) and the small nuclear ribonucleoprotein polypeptide N gene (SNRPN) in the human uterus and leiomyoma. Gynecol Obstet Invest 41 (1996) 50-54
    • (1996) Gynecol Obstet Invest , vol.41 , pp. 50-54
    • Hashimoto, K.1    Azuma, C.2    Kamiura, S.3    Koyama, M.4    Nobunaga, T.5    Tokugawa, Y.6
  • 24
    • 0032820908 scopus 로고    scopus 로고
    • Expression and imprinting of insulin-like growth factor II (IGF2) and H19 genes in uterine leiomyomas
    • Rainho C.A., Pontes A., and Rogatto S.R. Expression and imprinting of insulin-like growth factor II (IGF2) and H19 genes in uterine leiomyomas. Gynecol Oncol 74 (1999) 375-380
    • (1999) Gynecol Oncol , vol.74 , pp. 375-380
    • Rainho, C.A.1    Pontes, A.2    Rogatto, S.R.3
  • 25
    • 17744405954 scopus 로고    scopus 로고
    • Differential expression of Akt/protein kinase B, Bcl-2 and Bax proteins in human leiomyoma and myometrium
    • Kovacs K.A., Lengyel F., Kornyei J.L., Vertes Z., Szabo I., Sumegi B., et al. Differential expression of Akt/protein kinase B, Bcl-2 and Bax proteins in human leiomyoma and myometrium. J Steroid Biochem Mol Biol 87 (2003) 233-240
    • (2003) J Steroid Biochem Mol Biol , vol.87 , pp. 233-240
    • Kovacs, K.A.1    Lengyel, F.2    Kornyei, J.L.3    Vertes, Z.4    Szabo, I.5    Sumegi, B.6
  • 26
    • 2342489879 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 receptor mRNA expression and autophosphorylation in human myometrium and leiomyoma
    • Martin Chaves E.B., Brum I.S., Stoll J., Capp E., and Corleta H.E. Insulin-like growth factor 1 receptor mRNA expression and autophosphorylation in human myometrium and leiomyoma. Gynecol Obstet Invest 57 (2004) 210-213
    • (2004) Gynecol Obstet Invest , vol.57 , pp. 210-213
    • Martin Chaves, E.B.1    Brum, I.S.2    Stoll, J.3    Capp, E.4    Corleta, H.E.5
  • 27
    • 0035109727 scopus 로고    scopus 로고
    • Administration of somatostatin analogue reduces uterine and myoma volume in women with uterine leiomyomata
    • De Leo V., la Marca A., Morgante G., Severi F.M., and Petraglia F. Administration of somatostatin analogue reduces uterine and myoma volume in women with uterine leiomyomata. Fertil Steril 75 (2001) 632-633
    • (2001) Fertil Steril , vol.75 , pp. 632-633
    • De Leo, V.1    la Marca, A.2    Morgante, G.3    Severi, F.M.4    Petraglia, F.5
  • 28
    • 13244269807 scopus 로고    scopus 로고
    • Expression profile of tuberin and some potential tumorigenic factors in 60 patients with uterine leiomyomata
    • Wei J., Chiriboga L., Mizuguchi M., Yee H., and Mittal K. Expression profile of tuberin and some potential tumorigenic factors in 60 patients with uterine leiomyomata. Mod Pathol 18 (2005) 179-188
    • (2005) Mod Pathol , vol.18 , pp. 179-188
    • Wei, J.1    Chiriboga, L.2    Mizuguchi, M.3    Yee, H.4    Mittal, K.5
  • 29
    • 29144520613 scopus 로고    scopus 로고
    • Ethnic differences in expression of the dysregulated proteins in uterine leiomyomata
    • Wei J.J., Chiriboga L., Arslan A.A., Melamed J., Yee H., and Mittal K. Ethnic differences in expression of the dysregulated proteins in uterine leiomyomata. Hum Reprod 21 (2006) 57-67
    • (2006) Hum Reprod , vol.21 , pp. 57-67
    • Wei, J.J.1    Chiriboga, L.2    Arslan, A.A.3    Melamed, J.4    Yee, H.5    Mittal, K.6
  • 30
    • 0034708052 scopus 로고    scopus 로고
    • Promoter usage for insulin-like growth factor-II in cancerous and benign human breast, prostate, and bladder tissues, and confirmation of a 10th exon
    • Mineo R., Fichera E., Liang S.J., and Fujita-Yamaguchi Y. Promoter usage for insulin-like growth factor-II in cancerous and benign human breast, prostate, and bladder tissues, and confirmation of a 10th exon. Biochem Biophys Res Commun 268 (2000) 886-892
    • (2000) Biochem Biophys Res Commun , vol.268 , pp. 886-892
    • Mineo, R.1    Fichera, E.2    Liang, S.J.3    Fujita-Yamaguchi, Y.4
  • 31
    • 0037040971 scopus 로고    scopus 로고
    • Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk
    • Klotz D.M., Hewitt S.C., Ciana P., Raviscioni M., Lindzey J.K., Foley J., et al. Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk. J Biol Chem 277 (2002) 8531-8537
    • (2002) J Biol Chem , vol.277 , pp. 8531-8537
    • Klotz, D.M.1    Hewitt, S.C.2    Ciana, P.3    Raviscioni, M.4    Lindzey, J.K.5    Foley, J.6
  • 32
    • 0027945263 scopus 로고
    • Promoter-specific imprinting of the human insulin-like growth factor-II gene
    • Vu T.H., and Hoffman A.R. Promoter-specific imprinting of the human insulin-like growth factor-II gene. Nature 371 (1994) 714-717
    • (1994) Nature , vol.371 , pp. 714-717
    • Vu, T.H.1    Hoffman, A.R.2
  • 34
    • 0036714127 scopus 로고    scopus 로고
    • Akt regulates growth by directly phosphorylating Tsc2
    • Potter C.J., Pedraza L.G., and Xu T. Akt regulates growth by directly phosphorylating Tsc2. Nat Cell Biol 4 (2002) 658-665
    • (2002) Nat Cell Biol , vol.4 , pp. 658-665
    • Potter, C.J.1    Pedraza, L.G.2    Xu, T.3
  • 35
    • 0038362751 scopus 로고    scopus 로고
    • Akt activation promotes degradation of tuberin and FOXO3a via the proteasome
    • Plas D.R., and Thompson C.B. Akt activation promotes degradation of tuberin and FOXO3a via the proteasome. J Biol Chem 278 (2003) 12361-12366
    • (2003) J Biol Chem , vol.278 , pp. 12361-12366
    • Plas, D.R.1    Thompson, C.B.2
  • 37
    • 33947104498 scopus 로고    scopus 로고
    • A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas
    • Wang T., Zhang X., Obijuru L., Laser J., Aris V., Lee P., et al. A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas. Genes Chromosomes Cancer 46 (2007) 336-347
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 336-347
    • Wang, T.1    Zhang, X.2    Obijuru, L.3    Laser, J.4    Aris, V.5    Lee, P.6
  • 38
    • 0033842834 scopus 로고    scopus 로고
    • Crosstalk between the insulin-like growth factors and estrogens in breast cancer
    • Yee D., and Lee A.V. Crosstalk between the insulin-like growth factors and estrogens in breast cancer. J Mammary Gland Biol Neoplasia 5 (2000) 107-115
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 107-115
    • Yee, D.1    Lee, A.V.2
  • 39
    • 0034811867 scopus 로고    scopus 로고
    • Developmental regulation of placental insulin-like growth factor (IGF)-II and IGF-binding protein-1 and -2 messenger RNA expression during primate pregnancy
    • Zollers Jr. W.G., Babischkin J.S., Pepe G.J., and Albrecht E.D. Developmental regulation of placental insulin-like growth factor (IGF)-II and IGF-binding protein-1 and -2 messenger RNA expression during primate pregnancy. Biol Reprod 65 (2001) 1208-1214
    • (2001) Biol Reprod , vol.65 , pp. 1208-1214
    • Zollers Jr., W.G.1    Babischkin, J.S.2    Pepe, G.J.3    Albrecht, E.D.4
  • 40
    • 2442710348 scopus 로고    scopus 로고
    • Parent-of-origin-specific binding of nuclear hormone receptor complexes in the H19-Igf2 imprinting control region
    • Szabo P.E., Pfeifer G.P., and Mann J.R. Parent-of-origin-specific binding of nuclear hormone receptor complexes in the H19-Igf2 imprinting control region. Mol Cell Biol 24 (2004) 4858-4868
    • (2004) Mol Cell Biol , vol.24 , pp. 4858-4868
    • Szabo, P.E.1    Pfeifer, G.P.2    Mann, J.R.3
  • 41
    • 0035207630 scopus 로고    scopus 로고
    • Promoter-specific transcription of the IGF2 gene: a novel rapid, non-radioactive and highly sensitive protocol for mRNA analysis
    • Hartmann W., Waha A., Koch A., Albrecht S., Gray S.G., Ekstrom T.J., et al. Promoter-specific transcription of the IGF2 gene: a novel rapid, non-radioactive and highly sensitive protocol for mRNA analysis. Virchows Arch 439 (2001) 803-807
    • (2001) Virchows Arch , vol.439 , pp. 803-807
    • Hartmann, W.1    Waha, A.2    Koch, A.3    Albrecht, S.4    Gray, S.G.5    Ekstrom, T.J.6
  • 42
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
    • Inoki K., Li Y., Zhu T., Wu J., and Guan K.L. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 4 (2002) 648-657
    • (2002) Nat Cell Biol , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.L.5
  • 43
    • 0038433304 scopus 로고    scopus 로고
    • Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
    • Garami A., Zwartkruis F.J., Nobukuni T., Joaquin M., Roccio M., Stocker H., et al. Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2. Mol Cell 11 (2003) 1457-1466
    • (2003) Mol Cell , vol.11 , pp. 1457-1466
    • Garami, A.1    Zwartkruis, F.J.2    Nobukuni, T.3    Joaquin, M.4    Roccio, M.5    Stocker, H.6
  • 44
    • 0036342294 scopus 로고    scopus 로고
    • Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway
    • Manning B.D., Tee A.R., Logsdon M.N., Blenis J., and Cantley L.C. Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol Cell 10 (2002) 151-162
    • (2002) Mol Cell , vol.10 , pp. 151-162
    • Manning, B.D.1    Tee, A.R.2    Logsdon, M.N.3    Blenis, J.4    Cantley, L.C.5
  • 45
    • 0036645074 scopus 로고    scopus 로고
    • Aberrant expression of HMGA2 in uterine leiomyoma associated with loss of TSC2 tumor suppressor gene function
    • Hunter D.S., Klotzbucher M., Kugoh H., Cai S.L., Mullen J.P., Manfioletti G., et al. Aberrant expression of HMGA2 in uterine leiomyoma associated with loss of TSC2 tumor suppressor gene function. Cancer Res 62 (2002) 3766-3772
    • (2002) Cancer Res , vol.62 , pp. 3766-3772
    • Hunter, D.S.1    Klotzbucher, M.2    Kugoh, H.3    Cai, S.L.4    Mullen, J.P.5    Manfioletti, G.6
  • 46
    • 34547645033 scopus 로고    scopus 로고
    • Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer
    • Ma L., Teruya-Feldstein J., Bonner P., Bernardi R., Franz D.N., Witte D., et al. Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer. Cancer Res 67 (2007) 7106-7112
    • (2007) Cancer Res , vol.67 , pp. 7106-7112
    • Ma, L.1    Teruya-Feldstein, J.2    Bonner, P.3    Bernardi, R.4    Franz, D.N.5    Witte, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.