Identification of critical infection parameters to control helper-dependent adenoviral vector production

Journal of Biotechnology

Volumn 142, Issue 2, 2009, Pages 142-150

  Dormond, E ^a,b   Perrier, M ^b   Kamen, A ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b ÉCOLE POLYTECHNIQUE DE MONTRÉAL   (Canada)

Author keywords

Adenovirus; Gene therapy; HEK293 cells; Helper dependent adenoviral vector; Multiplicity of infection; Real time qPCR assay; Time of infection

Indexed keywords

ADENOVIRUS; GENE THERAPY; HEK293 CELLS; HELPER-DEPENDENT ADENOVIRAL VECTOR; MULTIPLICITY OF INFECTION; REAL-TIME QPCR ASSAY; TIME OF INFECTION;

CELL CULTURE; CONTAMINATION; GENETIC ENGINEERING;

VECTORS;

ADENOVIRUS VECTOR;

ARTICLE; CONTROLLED STUDY; HELPER VIRUS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PRODUCT RECOVERY; VIRAL CONTAMINATION; VIRAL GENE DELIVERY SYSTEM; VIRUS INFECTIVITY;

ADENOVIRIDAE; CELL LINE; GENE THERAPY; GENETIC VECTORS; GENOME, VIRAL; HELPER VIRUSES; HUMANS; KINETICS; POLYMERASE CHAIN REACTION; RECOMBINASES; VIRION; VIRUS CULTIVATION;

ADENOVIRIDAE;

EID: 67349258527     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2009.03.021     Document Type: Article

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