Stress-Induced Redistribution of Corticotropin-Releasing Factor Receptor Subtypes in the Dorsal Raphe Nucleus

Biological Psychiatry

Volumn 66, Issue 1, 2009, Pages 76-83

  Waselus, Maria ^a   Nazzaro, Cristiano ^b   Valentino, Rita J ^b   Van Bockstaele, Elisabeth J ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Antalarmin; behavioral coping strategies; corticotropin releasing hormone; immunoelectron microscopy; receptor trafficking; serotonin

Indexed keywords

CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; IMMUNOELECTRON MICROSCOPY; IN VIVO STUDY; INTERNALIZATION; MALE; MENTAL STRESS; NERVE CELL; NERVE CELL INHIBITION; NERVE CELL MEMBRANE; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; RAT; SWIMMING;

ACTION POTENTIALS; ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; MALE; MICROSCOPY, IMMUNOELECTRON; NEURONS; PROTEIN TRANSPORT; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; SEROTONIN; STRESS, PSYCHOLOGICAL; SWIMMING;

EID: 67349251529     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2009.02.014     Document Type: Article

References (37)

1. Gold P.W., Chrousos G.P., and Kellner C.H. Overview: Psychiatric implications of basic and clinical studies with corticotropin-releasing factor. Am J Psychol 141 (1984) 619-627
2. McEwen B.S. Stress, adaptation, and disease. Allostasis and allostatic load. Ann N Y Acad Sci 840 (1998) 33-44
3. Chappell P.B., Smith M.A., Kilts C.D., Bissette G., Ritchie J., Anderson C., et al. Alterations in corticotropin-releasing factor-like immunoreactivity in discrete rat brain regions after acute and chronic stress. J Neurol Sci 6 (1986) 2908-2914
4. Valentino R.J., and Commons K.G. Peptides that fine-tune the serotonin system. Neuropeptides 39 (2005) 1-8
5. Valentino R.J., and Van Bockstaele E.J. Convergent regulation of the locus coeruleus-norepinephrine system as an adaptive response to stress. Eur J Pharmacol 583 (2008) 194-203
6. Kirby L.G., Rice K., and Valentino R.J. Effects of corticotropin-releasing factor on neuronal activity in the serotonergic dorsal raphe nucleus. Neuropsychopharmacology 22 (2000) 148-162
7. Pernar L., Curtis A.L., Vale W.W., Rivier J.E., and Valentino R.J. Selective activation of corticotropin-releasing factor-2 receptors on neurochemically identified neurons in the rat dorsal raphe nucleus reveals dual actions. J Neurol Sci 24 (2004) 1305-1311
8. Price M.L., Curtis A.L., Kirby L.G., Valentino R.J., and Lucki I. Effects of corticotropin-releasing factor on brain serotonergic activity. Neuropsychopharmacology 18 (1998) 492-502
9. Price M.L., and Lucki I. Regulation of serotonin release in the lateral septum and striatum by corticotropin-releasing factor. J Neurol Sci 21 (2001) 2833-2841
10. Price M.L., Kirby L.G., Valentino R.J., and Lucki I. Evidence for corticotropin-releasing factor regulation of serotonin in the lateral septum during acute swim stress: Adaptation produced by repeated swim. Psychopharmacology 162 (2002) 406-414
11. Hammack S.E., Schmid M.J., LoPresti M.L., Der-Avakian A., Pellymounter M.A., Foster A.C., et al. Corticotropin-releasing hormone type 2 receptors in the dorsal raphe nucleus mediate the behavioral consequences of uncontrollable stress. J Neurol Sci 23 (2003) 1019-1025
12. Hammack S.E., Pepin J.L., DesMarteau J.S., Watkins L.R., and Maier S.F. Low doses of corticotropin-releasing hormone injected into the dorsal raphe nucleus block the behavioral consequences of uncontrollable stress. Behav Brain Res 147 (2003) 55-64
13. Curtis A.L., Pavcovich L.A., and Valentino R.J. Previous stress alters corticotropin-releasing factor neurotransmission in the locus coeruleus. Neuroscience 65 (1995) 541-550
14. Curtis A.L., Pavcovich L.A., and Valentino R.J. Long term regulation of locus coeruleus sensitivity to corticotropin-releasing factor by swim stress. J Pharmacol Exp Ther 289 (1999) 1211-1219
15. Reyes B.A., Valentino R.J., and Van Bockstaele E.J. Stress-induced intracellular trafficking of corticotropin-releasing factor receptors in rat locus coeruleus neurons. Endocrinology 149 (2008) 122-130
16. Reyes B.A., Fox K., Valentino R.J., and Van Bockstaele E.J. Agonist-induced internalization of corticotropin-releasing factor receptors in noradrenergic neurons of the rat locus coeruleus. Eur J Neurosci 23 (2006) 2991-2998
17. Day H.E., Greenwood B.N., Hammack S.E., Watkins L.R., Fleshner M., Maier S.F., et al. Differential expression of 5HT-1A, alpha 1b adrenergic, CRF-R1, and CRF-R2 receptor mRNA in serotonergic, gamma-aminobutyric acidergic, and catecholaminergic cells of the rat dorsal raphe nucleus. J Comp Neurol 474 (2004) 364-378
18. Leranth C., and Pickel V.M. Electron microscopic preembedding double-immunostaining methods. In: Heimer L., and Zaborszky L. (Eds). Neuroanatomical Tract-Tracing Methods 2: Recent Progress. 2nd ed. (1989), Plenum, New York 129-172
19. Peters A., Palay S.L., and Webster H.D. The Fine Structure of the Nervous System: Neurons and their Supporting Cells. 3rd ed. (1991), Oxford University Press
20. van Praag H.M. Depression, suicide, and serotonin metabolism in the brain. In: Post R.M., and Ballenger J.C. (Eds). Neurobiology of Mood Disorders (1984), Williams and Wilkins, Baltimore, MD 601-618
21. Nordstrom P., and Asperg M. Suicide risk and serotonin. Int Clin Psychopharmacol 6 suppl 6 (1992) 6-21
22. Cowen P.J. Serotonin receptor subtypes in depression: Evidence from studies in neuroendocrine regulation. Clin Neuropharmacol 16 suppl 3 (1993) S6-S18
23. Lesch K.P. 5-HT1A receptor responsivity in anxiety disorders and depression. Prog Neuropsychopharmacol Biol Psychiatry 15 (1991) 723-733
24. Mann J.J., Malone K.M., Diegl D.J., PErel J., Cooper T.B., and Mintun M.A. Demonstration in vivo of reduced serotonin responsivity in the brain of untreated depressed patients. Am J Psychol 153 (1996) 174-182
25. Heils A., Mossner R., and Lesch K.P. The human serotonin transporter gene polymorphism-basic research and clinical implications. J Neural Transm 104 (1997) 1005-1014
26. Nemeroff C.B. The corticotropin-releasing factor (CRF) hypothesis of depression: New findings and new directions. Mol Psychiatry 1 (1996) 336-342
27. Swanson L.W., Sawchenko P.E., Rivier J., and Vale W. Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in rat brain: An immunohistochemical study. Neuroendocrinology 36 (1983) 165-186
28. Valentino R.J., Liouterman L., and Van Bockstaele E.J. Evidence for regional heterogeneity in corticotropin-releasing factor interactions in the dorsal raphe nucleus. J Comp Neurol 435 (2001) 450-463
29. Waselus M., Valentino R.J., and Van Bockstaele E.J. Ultrastructural evidence for a role of gamma-aminobutyric acid in mediating the effects of corticotropin-releasing factor on the rat dorsal raphe serotonin system. J Comp Neurol 482 (2005) 155-165
30. Van Pett K., Viau V., bittencourt J.C., Chan R.K., Li H.Y., Arias C., et al. Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse. J Comp Neurol 428 (2000) 191-212
31. Lukkes J.L., Forster G.L., Renner K.J., and Summers C.H. Corticotropin-releasing factor 1 and 2 receptors in the dorsal raphe differentially affect serotonin release in the nucleus accumbens. Eur J Pharmacol 578 (2008) 185-193
32. Staub D.R., Spiga F., and Lowry C.A. Urocortin 2 increases c-Fos expression in topographically organized subpopulations of serotonergic neurons in the rat dorsal raphe nucleus. Brain Res 1044 (2005) 176-189
33. Amat J., Tamblyn J.P., Paul E.D., Bland S.T., Amat P., Foster A.C., et al. Microinjection of urocortin 2 into the dorsal raphe nucleus activates serotonergic neurons and increases extracellular serotonin in the basolateral amygdala. Neuroscience 129 (2004) 509-519
34. Rutz C., Renner A., Alken M., Schulz K., Beyermann M., Wiesner B., et al. The corticotropin-releasing factor receptor type 2a contains an N-terminal pseudo signal peptide. J Biol Chem 281 (2006) 24910-24921
35. Kirby L.G., and Lucki I. Interaction between the forced swimming test and fluoxetine treatment on extracellular 5-HT and 5-HIAA in the rat. J Pharmacol Exp Ther 282 (1997) 967-976
36. Kirby L.G., and Lucki I. The effect of repeated exposure to forced swimming on extracellular levels of 5-hydroxytryptamine in the rat. Stress 2 (1998) 251-263
37. Hillhouse E.W., and Grammatopoulos D.K. The molecular mechanisms underlying the regulation of the biological activity of corticotropin-releasing hormone receptors: implications for physiology and pathophysiology. Endocr Rev 27 (2006) 260-286