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Ramamoorthy (Ed), Taylor & Francis, New York
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In: Ramamoorthy (Ed). NMR Spectroscopy of Biological Solids (2006), Taylor & Francis, New York
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(2006)
NMR Spectroscopy of Biological Solids
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4
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10944242116
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*Reports a comprehensive analysis of PISEMA solid-state NMR spectroscopy to study biological solids.
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Ramamoorthy A., Wei Y., and Lee D.K. Ann. Rep. NMR Spectrosc. 52 (2004) 1-52. *Reports a comprehensive analysis of PISEMA solid-state NMR spectroscopy to study biological solids.
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(2004)
Ann. Rep. NMR Spectrosc.
, vol.52
, pp. 1-52
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Ramamoorthy, A.1
Wei, Y.2
Lee, D.K.3
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6
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4344704702
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*Reports the challenges and various approaches for the investigation of membrane protein structures using NMR spectroscopy.
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Opella S.J., and Marassi F.M. Chem. Rev. 104 (2004) 3587-3606. *Reports the challenges and various approaches for the investigation of membrane protein structures using NMR spectroscopy.
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(2004)
Chem. Rev.
, vol.104
, pp. 3587-3606
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Opella, S.J.1
Marassi, F.M.2
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12
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33748935159
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*This article presents the importances of antimicrobial peptides and multiple roles of LL-37, the only human member of the cathelicidin family of antimicrobial peptides. It also presents structural, mechanism of membrane disruption, and functional studies on LL-37.
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Dürr U.H.N., Sudheendra U.S., and Ramamoorthy A. BBA-Biomembranes 1758 (2006) 1408-1425. *This article presents the importances of antimicrobial peptides and multiple roles of LL-37, the only human member of the cathelicidin family of antimicrobial peptides. It also presents structural, mechanism of membrane disruption, and functional studies on LL-37.
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(2006)
BBA-Biomembranes
, vol.1758
, pp. 1408-1425
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Dürr, U.H.N.1
Sudheendra, U.S.2
Ramamoorthy, A.3
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15
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0037165196
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*Introduced the importances of popular AMPs called magainins.
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Zasloff M. Nature 415 (2002) 389-395. *Introduced the importances of popular AMPs called magainins.
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(2002)
Nature
, vol.415
, pp. 389-395
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Zasloff, M.1
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16
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0023854883
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*Introduced the importances of popular AMPs called magainins.
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Zasloff M., Martin B., and Chen H.C. Proc. Natl. Acad. Sci. 85 (1988) 910-913. *Introduced the importances of popular AMPs called magainins.
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Proc. Natl. Acad. Sci.
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Zasloff, M.1
Martin, B.2
Chen, H.C.3
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18
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0038052326
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*This article presents the mechanism of membrane disruption by the human antimicrobial peptide LL-37. Atomic-level resolution membrane orientation and peptide-induced structural disorder near the head group region of lipids in model phospholipid membranes were determined using solid-state NMR experiments.
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Wildman K.A.H., Lee D.K., and Ramamoorthy A. Biochemistry 42 (2003) 6545. *This article presents the mechanism of membrane disruption by the human antimicrobial peptide LL-37. Atomic-level resolution membrane orientation and peptide-induced structural disorder near the head group region of lipids in model phospholipid membranes were determined using solid-state NMR experiments.
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(2003)
Biochemistry
, vol.42
, pp. 6545
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Wildman, K.A.H.1
Lee, D.K.2
Ramamoorthy, A.3
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19
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3142543171
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2H NMR spectroscopy using multilamelar vesicles. An excellent model developed based on solid-state NMR experimental data used to explain the function of LL-37.
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2H NMR spectroscopy using multilamelar vesicles. An excellent model developed based on solid-state NMR experimental data used to explain the function of LL-37.
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(2004)
Biochemistry
, vol.43
, pp. 8459-8469
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Henzler-Wildman, K.A.1
Martinez, G.V.2
Brown, M.F.3
Ramamoorthy, A.4
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20
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43949083747
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Porcelli F., Verardi R., Shi L., Henzler-Wildman K.A., Ramamoorthy A., and Veglia G. Biochemistry 47 (2008) 5565-5572
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(2008)
Biochemistry
, vol.47
, pp. 5565-5572
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Porcelli, F.1
Verardi, R.2
Shi, L.3
Henzler-Wildman, K.A.4
Ramamoorthy, A.5
Veglia, G.6
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21
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50249100288
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14N solid-state NMR investigation of the membrane orientation of peptides using mechanically aligned model membranes. An approach to measure the oligomerization of LL-37 is reported.
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14N solid-state NMR investigation of the membrane orientation of peptides using mechanically aligned model membranes. An approach to measure the oligomerization of LL-37 is reported.
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(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 6424-6429
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Ramamoorthy, A.1
Lee, D.K.2
Santos, J.S.3
Henzler-Wildman, K.A.4
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22
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0035997051
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*Solid-state NMR experimental approaches to determine the membrane orientation and function of pardaxin and their dependence on the membrane composition are reported. The role of cholesterol present in mammalian membranes towards the selectivity of an AMP is demonstrated using solid-state NMR experiments on mechanically aligned lipid bilayers containing pardaxin.
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Hallock K.J., Lee D.-K., Omnaas J., Mosberg H.I., and Ramamoorthy A. Biophys. J. 83 (2002) 1004-1013. *Solid-state NMR experimental approaches to determine the membrane orientation and function of pardaxin and their dependence on the membrane composition are reported. The role of cholesterol present in mammalian membranes towards the selectivity of an AMP is demonstrated using solid-state NMR experiments on mechanically aligned lipid bilayers containing pardaxin.
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(2002)
Biophys. J.
, vol.83
, pp. 1004-1013
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Hallock, K.J.1
Lee, D.-K.2
Omnaas, J.3
Mosberg, H.I.4
Ramamoorthy, A.5
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23
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7744229375
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Porcelli F., Buck B., Lee D.K., Hallock K.J., Ramamoorthy A., and Veglia G. J. Biol. Chem. 279 (2004) 46815-46823
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(2004)
J. Biol. Chem.
, vol.279
, pp. 46815-46823
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Porcelli, F.1
Buck, B.2
Lee, D.K.3
Hallock, K.J.4
Ramamoorthy, A.5
Veglia, G.6
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24
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0037961563
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*Toroidal-pore mechanism of membrane disruption by the most potent AMP from the magainin family, pexiganan (or MSI-78), is determined using solid-state NMR experiments. The pore geometry and the role of membrane composition on the peptide function are also reported.
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Hallock K.J., Lee D.K., and Ramamoorthy A. Biophys. J. 84 (2003) 3052. *Toroidal-pore mechanism of membrane disruption by the most potent AMP from the magainin family, pexiganan (or MSI-78), is determined using solid-state NMR experiments. The pore geometry and the role of membrane composition on the peptide function are also reported.
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(2003)
Biophys. J.
, vol.84
, pp. 3052
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Hallock, K.J.1
Lee, D.K.2
Ramamoorthy, A.3
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25
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33745747109
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Ramamoorthy A., Thennarasu S., Lee D.K., Tan A., and Maloy L. Biophys. J. 91 (2006) 206-216
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(2006)
Biophys. J.
, vol.91
, pp. 206-216
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Ramamoorthy, A.1
Thennarasu, S.2
Lee, D.K.3
Tan, A.4
Maloy, L.5
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33646474970
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Porcelli F., Buck-Koehntop B., Thennarasu S., Ramamoorthy A., and Veglia G. Biochemistry 45 (2006) 5793-5799
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(2006)
Biochemistry
, vol.45
, pp. 5793-5799
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Porcelli, F.1
Buck-Koehntop, B.2
Thennarasu, S.3
Ramamoorthy, A.4
Veglia, G.5
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29
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3042736841
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*This study presents the measurement of intermolecular dipolar couplings using REDOR to determine the lipid-AMP interaction and location of the peptide in model membranes.
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Toke O., Maloy W.L., Kim S.J., Blazyk J., and Schaefer J. Biophys. J. 87 (2004) 662-674. *This study presents the measurement of intermolecular dipolar couplings using REDOR to determine the lipid-AMP interaction and location of the peptide in model membranes.
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(2004)
Biophys. J.
, vol.87
, pp. 662-674
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Toke, O.1
Maloy, W.L.2
Kim, S.J.3
Blazyk, J.4
Schaefer, J.5
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35
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0036228299
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*A method to prepare well-hydrated mechanically aligned lipid bilayers using sublimable solids like naphthalene for solid-state NMR studies is reported. This approach has been shown to provide stable well-aligned bilayers even for a model membrane composition mimicking bacterial membranes.
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Hallock K.J., Henzler Wildman K.A., Lee D.K., and Ramamoorthy A. Biophys. J. 82 (2002) 2499. *A method to prepare well-hydrated mechanically aligned lipid bilayers using sublimable solids like naphthalene for solid-state NMR studies is reported. This approach has been shown to provide stable well-aligned bilayers even for a model membrane composition mimicking bacterial membranes.
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(2002)
Biophys. J.
, vol.82
, pp. 2499
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Hallock, K.J.1
Henzler Wildman, K.A.2
Lee, D.K.3
Ramamoorthy, A.4
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37
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Ramamoorthy A., Kandasamy S.K., Lee D.K., Kidambi S., and Larson R.G. Biochemistry 46 (2007) 965-975
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(2007)
Biochemistry
, vol.46
, pp. 965-975
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Ramamoorthy, A.1
Kandasamy, S.K.2
Lee, D.K.3
Kidambi, S.4
Larson, R.G.5
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38
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Kandasamy S.K., Lee D.K., Nanga R.P.R., Xu J., Santos J.S., Larson R.G., and Ramamoorthy A. BBA-Biomembranes 1788 (2009) 686-695
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(2009)
BBA-Biomembranes
, vol.1788
, pp. 686-695
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Kandasamy, S.K.1
Lee, D.K.2
Nanga, R.P.R.3
Xu, J.4
Santos, J.S.5
Larson, R.G.6
Ramamoorthy, A.7
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39
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57549112908
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*This paper presents 19F solid-state NMR method to determine the temperature dependent change in the membrane orientation by PGLa.
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Afonin S., Grage S.L., Ieronimo M., Wadhwani P., and Ulrich A.S. J. Am. Chem. Soc. 130 (2008) 16512-16514. *This paper presents 19F solid-state NMR method to determine the temperature dependent change in the membrane orientation by PGLa.
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(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 16512-16514
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Afonin, S.1
Grage, S.L.2
Ieronimo, M.3
Wadhwani, P.4
Ulrich, A.S.5
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43
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Thennarasu S., Lee D.K., Tan A., Kari U.P., and Ramamoorthy A. Biochim. Biophys. Acta 1711 (2005) 49-58
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(2005)
Biochim. Biophys. Acta
, vol.1711
, pp. 49-58
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Thennarasu, S.1
Lee, D.K.2
Tan, A.3
Kari, U.P.4
Ramamoorthy, A.5
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44
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Glaser R.W., Sachse C., Dürr U.H.N., Wadhwani P., Afonin S., Strandberg E., and Ulrich A.S. Biophys. J. 88 (2005) 3392-3397
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Biophys. J.
, vol.88
, pp. 3392-3397
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Glaser, R.W.1
Sachse, C.2
Dürr, U.H.N.3
Wadhwani, P.4
Afonin, S.5
Strandberg, E.6
Ulrich, A.S.7
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45
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26044476880
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Thennarasu S., Lee D.K., Poon A., Kawulka K.E., Vederas J.C., and Ramamoorthy A. Chem. Phys. Lipids 137 (2005) 38-51
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(2005)
Chem. Phys. Lipids
, vol.137
, pp. 38-51
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Thennarasu, S.1
Lee, D.K.2
Poon, A.3
Kawulka, K.E.4
Vederas, J.C.5
Ramamoorthy, A.6
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46
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Ramamoorthy A., Thennarasu S., Tan A., Lee D.K., Clayberger C., and Krensky A.M. BBA-Biomembranes 1758 (2006) 154-163
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(2006)
BBA-Biomembranes
, vol.1758
, pp. 154-163
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Ramamoorthy, A.1
Thennarasu, S.2
Tan, A.3
Lee, D.K.4
Clayberger, C.5
Krensky, A.M.6
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54
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0033178532
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Oren Z., Lerman J.C., Gudmundsson G.H., Agerberth B., and Shai Y. Biochem. J. 341 (1999) 501-513
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Shai, Y.5
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56
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How far can the sensitivity of NMR be increased?
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*Limitation and advantages of various methods to enhance the sensitivity of NMR detection are discussed.
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Fujiwara T., and Ramamoorthy A. How far can the sensitivity of NMR be increased?. Ann. Rep. NMR Spectrosc. 58 (2006) 155-175. *Limitation and advantages of various methods to enhance the sensitivity of NMR detection are discussed.
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Ann. Rep. NMR Spectrosc.
, vol.58
, pp. 155-175
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Fujiwara, T.1
Ramamoorthy, A.2
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Gottler L.M., Lee H.Y., Shelburne C.E., Ramamoorthy A., and Marsh E.N.G. Chem. Biochem. 9 (2008) 370-373
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(2008)
Chem. Biochem.
, vol.9
, pp. 370-373
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Gottler, L.M.1
Lee, H.Y.2
Shelburne, C.E.3
Ramamoorthy, A.4
Marsh, E.N.G.5
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58
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Gottler L.M., de la R., Bea S., Shelburne C.E., Ramamoorthy A., and Marsh E.N.G. Biochemistry 47 (2008) 9243-9250
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(2008)
Biochemistry
, vol.47
, pp. 9243-9250
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Gottler, L.M.1
de la, R.2
Bea, S.3
Shelburne, C.E.4
Ramamoorthy, A.5
Marsh, E.N.G.6
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60
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Mecke A., Lee D.K., Ramamoorthy A., Orr B.G., and Holl M.M.B. Biophys. J. 89 (2005) 4043-4050
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Biophys. J.
, vol.89
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Mecke, A.1
Lee, D.K.2
Ramamoorthy, A.3
Orr, B.G.4
Holl, M.M.B.5
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61
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Mecke A., Lee D.K., Ramamoorthy A., Orr G., and Banazak Holl M.M. Langmuir 21 (2005) 8588-8590
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(2005)
Langmuir
, vol.21
, pp. 8588-8590
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Mecke, A.1
Lee, D.K.2
Ramamoorthy, A.3
Orr, G.4
Banazak Holl, M.M.5
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Mecke A., Uppuluri S., Sassanella T.M., Lee D.K., Ramamoorthy A., Baker Jr. J.R., Orr B.G., and Banaszak Holl M.M. Chem. Phys. Lipids 132 (2004) 3-14
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(2004)
Chem. Phys. Lipids
, vol.132
, pp. 3-14
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Mecke, A.1
Uppuluri, S.2
Sassanella, T.M.3
Lee, D.K.4
Ramamoorthy, A.5
Baker Jr., J.R.6
Orr, B.G.7
Banaszak Holl, M.M.8
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