Studies of chitosan/Kollicoat SR 30D film-coated tablets for colonic drug delivery

International Journal of Pharmaceutics

Volumn 375, Issue 1-2, 2009, Pages 8-15

  Li Fang, Fan ^a,b   Wei, He ^b,c   Yong Zhen, Chang ^d   Bai, Xiang ^b   Qing, Du ^b   Feng, Wang ^e   Min, Qin ^f   De Ying, Cao ^b  

^a Hebei Yiling Pharmaceutical Group   (China)

^b HEBEI MEDICAL UNIVERSITY   (China)

^c CSPC Pharmaceutical Technology Co Ltd   (China)

^d Xingtai Medical College   (China)

^e CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^f Liuzhou Worker Hospital   (China)

Author keywords

Chitosan; Colonic delivery; Film coating; Kollicoat SR30D; Pharmacokinetics

Indexed keywords

BACTERIAL ENZYME; BETA GLUCOSIDASE; CHITOSAN; POLYMER; POLYVINYL ACETATE; THEOPHYLLINE;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL COMPOSITION; COLON ABSORPTION; CONTROLLED STUDY; DRUG RELEASE; FILM COATING; IN VITRO STUDY; IN VIVO STUDY; INTESTINE FLUID; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH JUICE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; BRONCHODILATOR AGENTS; CHITOSAN; COLON; DOGS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GASTRIC JUICE; INTESTINAL SECRETIONS; MALE; POLYVINYLS; RATS; TABLETS; THEOPHYLLINE;

EID: 67349239048     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.03.023     Document Type: Article

References (45)

1. Adkin D.A., Kenyon C.J., Lerner E.I., Landau I., Strauss E., Caron D., Penhasi A., Rubinstein A., and Wilding I.R. The use of scintigraphy to provide "proof of concept" for novel polysaccharide preparations designed for colonic drug delivery. Pharm. Res. 14 (1997) 103-107
2. Akhgari A., Farahmand F., Afrasiabi Garekani H., Sadeghi F., and Vandamme T.F. Permeability and swelling studies on free films containing inulin in combination with different polymethacrylates aimed for colonic drug delivery. Eur. J. Pharm. Sci. 28 (2006) 307-314
3. Basit A.W., Podczeck F., Newton J.M., Waddington W.A., Ell P.J., and Lacey L.F. The use of formulation technology to assess regional gastrointestinal drug absorption in humans. Eur. J. Pharm. Sci. 21 (2004) 179-189
4. Brondsted H., and Kopecek J. Hydrogels for sitespecific oral drug delivery, synthesis and characterization. Biomaterials 12 (1991) 584
5. Chourasia M.K., and Jain S.K. Polysaccharides for colon targeted drug delivery. Drug Deliv. 11 (2004) 129-148
6. 13C] glucose microspheres as a model for drug delivery to the colon. J. Control. Release 40 (1996) 123-131
7. Finegold S.M., Sutter V.L., Sugihara P.T., Elder H.A., Lehmann S.M., and Phillips R.L. Fecal microbial flora in Seventh Day Adventist populations and control subjects. Am. J. Clin. Nutr. 30 (1977) 1781-1792
8. Gamelin E., Boisdron-Celle M., Delva R., Regimbeau C., Cailleux P.E., and Alleaume C. Long-term weekly treatment of colorectal metastatic cancer with fluorouracil and leucovorin: results of a multicentric prospective trial of fluorouracil dosage optimization by pharmacokinetic monitoring in 152 patients. J. Clin. Oncol. 16 (1998) 1470-1478
9. Ghaffari A., Avadi M.R., Moghimi H.R., Oskoui M., Bayati K., and Rafiee-Tehrani M. Mechanistic analysis of drug release from theophylline pellets coated by films containing pectin, chitosan and Eudragit RS. Drug Dev. Ind. Pharm. 34 (2008) 390-402
10. Gliko-Kabir I., Yagen B., Baluom M., and Rubinstein A. Phosphated crosslinked guar for colon-specific drug delivery. II. In vitro and in vivo evaluation. J. Control. Release 63 (2000) 129-134
11. Han M., Fang Q.L., Zhan H.W., Luo T., Liang W.Q., and Gao J.Q. In vitro and in vivo evaluation of a novel capsule for colon-specific drug delivery. J. Pharm. Sci. (2008)
12. Haupt S., Zioni T., Gati I., Kleinstern J., and Rubinstein A. Luminal delivery and dosing considerations of local celecoxib administration to colorectal cancer. Eur. J. Pharm. Sci. 28 (2006) 204-211
13. Hawksworth G., Drasar B.S., and Hill M.J. Intestinal bacteria and hydrolysis of glycosidic bonds. J. Med. Microbiol. 4 (1971) 451-459
14. Hayashi T., Kanbe H., Okada M., Kawase I., Ikeda Y., Onuki Y., Kaneko T., and Sonobe T. In vitro and in vivo sustained-release characteristics of theophylline matrix tablets and novel cluster tablets. Int. J. Pharm. 341 (2007) 105-113
15. He W., Du Q., Cao D.Y., Xiang B., and Fan L.F. In-vitro and in-vivo studies of pectin/ethylcellulosefilm-coated pellets of 5-fluorouracil for colonic targeting. J. Pharm. Pharmacol. 60 (2008) 35-44
16. He W., Du Q., Cao D.Y., Xiang B., and Fan L.F. Study on colon-specific pectin/ethylcellulose film-coated 5-fluorouracil pellets in rats. Int. J. Pharm. 348 (2008) 35-45
17. He W., Fan L.F., Du Q., Xiang B., Chang Y.Z., and Cao D.Y. An investigation into the characteristics of chitosan/Kollicoat SR30D free films for colonic delivery. Eur. J. Pharm. Biopharm. (2008) 10.1016/j.ejpb.2008.10.017
18. Jain A., Gupta Y., and Jain S.K. Azo-chemistry and its potential for colonic delivery. Crit. Rev. Ther. Drug Carrier Syst. 23 (2006) 349-400
19. Jain A., Gupta Y., and Jain S.K. Perspectives of biodegradable natural polysaccharides for site-specific drug delivery to the colon. J. Pharm. Pharm. Sci. 10 (2007) 86-128
20. Ji C., Xu H., and Wu W. In vitro evaluation and pharmacokinetics in dogs of guar gum and Eudragit FS30D-coated colon-targeted pellets of indomethacin. J. Drug Target. 15 (2007) 123-131
21. Jung Y., Kim H.H., Kim H., Kong H., Choi B., Yang Y., and Kim Y. Evaluation of 5-aminosalicyltaurine as a colon-specific prodrug of 5-aminosalicylic acid for treatment of experimental colitis. Eur. J. Pharm. Sci. 28 (2006) 26-33
22. Korsmeyer R.W., Gurny R., Docler E., Buri P., and Peppas N.A. Mechanism of solute release from porous hydrophilic polymers. Int. J. Pharm. 15 (1983) 25-35
23. Kosaraju S.L. Colon targeted delivery systems: review of polysaccharides for encapsulation and delivery. Crit. Rev. Food Sci. Nutr. 45 (2005) 251-258
24. Kuksal A., Tiwary A.K., Jain N.K., and Jain S. Formulation and in vitro, in vivo evaluation of extended-release matrix tablet of zidovudine: influence of combination of hydrophilic and hydrophobic matrix formers. AAPS PharmSciTech 7 (2006) E1
25. Langer R.S., and Peppas N.A. Present and future applications of biomaterials in controlled drug delivery systems. Biomaterials 2 (1981) 201-214
26. Larsen C., Harboe E., Johansen M., and Olesen H.P. Macromolecular prodrugs. XVI. Colon-targeted delivery-comparison of the rate of release of naproxen from dextran ester prodrugs in homogenates of various segments of the pig gastrointestinal (GI) tract. Pharm. Res. 6 (1989) 995-999
27. McConnell E.L., Short M.D., and Basit A.W. An in vivo comparison of intestinal pH and bacteria as physiological trigger mechanisms for colonic targeting in man. J. Control. Release 130 (2008) 154-160
28. Milojevic S., Newton J.M., and Cummings J.H. Amylose as coating for drug delivery to the colon: preparation and in vitro evaluation using 5-aminosalicylic acid pellets. J. Control. Release 38 (1996) 75-84
29. Milojevic S., Newton J.M., Cummings J.H., Gibson G.R., Botham R.L., Ring S.G., Stockham M., and Allwood M.C. Amylose as coating for drug delivery to the colon: preparation and in vitro evaluation using glucose pellets. J. Control. Release 38 (1996) 85-94
30. Mo L.K., Du Q., and Liao J. Preparation and Influence factors of theophylline pulsatile capsules controlled byerodible plugs. Chin. J. Pharm. 36 (2005) 0613-0604
31. Mockel J.E., and Lippold B.C. Zero order release from hydrocolloid matrices. Pharm. Res. 10 (1993) 1066-1070
32. Nunthanid J., Huanbutta K., Luangtana-Anan M., Sriamornsak P., Limmatvapirat S., and Puttipipatkhachorn S. Development of time-, pH-, and enzyme-controlled colonic drug delivery using spray-dried chitosan acetate and hydroxypropyl methylcellulose. Eur. J. Pharm. Biopharm. 68 (2008) 253-259
33. Patel R.P., and Patel M.M. Physical-chemical characterization and in vitro dissolution behavior of sivastatin-cyclodextrin inclusion compunds. Drug Deliv. Tech. 7 (2007) 51-56. http://www.drugdeliverytech-online.com/drugdelivery/200705/%3Fpg=200755 (http://www.drugdeliverytech-online.com/drugdelivery/200705/?pg=200755)
34. Rowhmd I.R. Factors affecting metabolic activity of the intestinal microflora. Drug Metab. Rev. 19 (1988) 243-261
35. Ryde E.M. Low molecular weight azo compounds. In: Friend D.R. (Ed). Oral Colon-Specific Drug Delivery (1992), CRC Press, Boca Raton 143
36. Saffran M., Kumar G.S., Savariar C., Burnham J.C., Williams F., and Neckers D.C. A new approach to the oral administration of insulin and other peptide drugs. Science 233 (1986) 1081-1084
37. Salyers A.A., and Leedle J.A. In: Hentge D.J. (Ed). Carbohydrate Metabolism in the Human Colon (1983), Academic Press, New York 129-146
38. Shimono N., Takatori T., Ueda M., Mori M., Higashi Y., and Nakamura Y. Chitosan dispersed system for colon-specific drug delivery. Int. J. Pharm. 245 (2002) 45-54
39. Sinha V.R., and Kumria R. Microbially triggered drug delivery to the colon. Eur. J. Pharm. Sci. 18 (2003) 3-18
40. Tanigawara Y., Yamaoka K., Nakagawa T., and UNO T. New method for the evaluation of in vitro dissolution time and disintegration time. Chem. Pharm. Bull. 30 (1982) 1088-1090
41. Tozaki H., Komoike J., Tada C., Maruyama T., Terabe A., Suzuki T., Yamamoto A., and Muranishi S. Chitosan capsules for colon-specific drug delivery: improvement of insulin absorption from the rat colon. J. Pharm. Sci. 86 (1997) 1016-1021
42. Van den Mooter G., Samyn C., and Kinget R. Characterization of colon-specific azo polymers: a study of the swelling properties and permeability of isolated polymers films. Int. J. Pharm. 111 (1994) 127-136
43. Wilson P.J., and Basit A.W. Exploiting gastrointestinal bacteria to target drugs to the colon: an in vitro study using amylose coated tablets. Int. J. Pharm. 300 (2005) 89-94
44. Yang L. Biorelevant dissolution testing of colon-specific delivery systems activated by colonic microflora. J. Control. Release 125 (2008) 77-86
45. Zhang H., Alsarra I.A., and Neau S.H. An in vitro evaluation of a chitosan-containing multiparticulate system for macromolecule delivery to the colon. Int. J. Pharm. 239 (2002) 197-205