Formulation and in vitro, in vivo evaluation of extended-release matrix tablet of zidovudine: Influence of combination of hydrophilic and hydrophobic matrix formers

AAPS PharmSciTech

Volumn 7, Issue 1, 2006, Pages

  Kuksal, Atul ^a   Tiwary, Ashok K ^a   Jain, Narendra K ^b   Jain, Subheet ^a  

^a PUNJABI UNIVERSITY   (India)

^b DR H S GOUR UNIVERSITY   (India)

Author keywords

Anti HIV drug; Matrix tablets; Mechanism; Scanning electron microscopy; Sustained release; Zidovudine

Indexed keywords

ETHYL CELLULOSE; EUDRAGIT; ZIDOVIR; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DIFFUSION; DRUG EFFICACY; DRUG RELEASE; DRUG SOLUBILITY; FEMALE; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MATRIX TABLET; NONHUMAN; PATIENT COMPLIANCE; RABBIT; SCANNING ELECTRON MICROSCOPY; SUSTAINED RELEASE FORMULATION; TABLET SURFACE; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; PH; SOLUBILITY; TABLET;

ANIMALS; ANTI-HIV AGENTS; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; FEMALE; HYDROGEN-ION CONCENTRATION; MALE; MICROSCOPY, ELECTRON, SCANNING; RABBITS; SOLUBILITY; TABLETS; ZIDOVUDINE;

EID: 30544451014     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt070101     Document Type: Article

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