The Plasmodium HU homolog, which binds the plastid DNA sequence-independent manner, is essential for the parasite's survival

FEBS Letters

Volumn 583, Issue 9, 2009, Pages 1446-1450

  Sasaki, Narie ^a,b   Hirai, Makoto ^c   Maeda, Katsura ^b   Yui, Ryoko ^a   Itoh, Kie ^d   Namiki, Syoko ^a   Morita, Teppei ^a   Hata, Masayuki ^e   Murakami Murofushi, Kimiko ^b   Matsuoka, Hiroyuki ^c   Kita, Kiyoshi ^e   Sato, Shigeharu ^f  

^a NAGOYA UNIVERSITY   (Japan)

^b OCHANOMIZU UNIVERSITY   (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

DNA binding protein; HU; Knock out; Plasmodium berghei; Plasmodium falciparum; Plastid

Indexed keywords

HU PROTEIN;

ARTICLE; BACTERIAL GENOME; DNA BINDING; DNA SEQUENCE; ESCHERICHIA COLI; GENE TARGETING; NONHUMAN; PARASITE SURVIVAL; PLASMODIUM FALCIPARUM; PLASTID; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; DNA, PROTOZOAN; GENE KNOCKOUT TECHNIQUES; GENETIC COMPLEMENTATION TEST; PLASMODIUM FALCIPARUM; PLASTIDS; PROTOZOAN PROTEINS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM;

EID: 67349237428     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.03.071     Document Type: Article

References (20)

1. Wilson R.J.M., et al. Complete gene map of the plastid-like DNA of the malaria parasite Plasmodium falciparum. J. Mol. Biol. 261 (1996) 155-172
2. Ralph S.A., et al. Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast. Nat. Rev. Microbiol. 2 (2004) 203-216
3. Dahl E.L., and Rosenthal P.J. Apicoplast translation, transcription and genome replication: targets for antimalarial antibiotics. Trends Parasitol. 24 (2008) 279-284
4. Sato N., Terasawa K., Miyajima K., and Kabeya Y. Organization, developmental dynamics, and evolution of plastid nucleoids. Int. Rev. Cytol. 232 (2003) 217-262
5. Swinger K.K., and Rice P.A. IHF and HU: flexible architects of bent DNA. Curr. Opin. Struct. Biol. 14 (2004) 28-35
6. Pettijohn D.E. Histone-like proteins and bacterial chromosome structure. J. Biol. Chem. 263 (1988) 12793-12796
7. Bramhill D., and Kornberg A. A model for initiation at origins of DNA replication. Cell 54 (1988) 915-918
8. Aki T., and Adhya S. Repressor induced site-specific binding of HU for transcriptional regulation. EMBO J. 16 (1997) 3666-3674
9. Dri A.M., Moreau P.L., and Rouviere-Yaniv J. Role of the histone-like proteins OsmZ and HU in homologous recombination. Gene 120 (1992) 11-16
10. Kobayashi T., Takahara M., Miyagishima S.Y., Kuroiwa H., Sasaki N., Ohta N., Matsuzaki M., and Kuroiwa T. Detection and localization of a chloroplast-encoded HU-like protein that organizes chloroplast nucleoids. Plant Cell 14 (2002) 1579-1589
11. Wu H., and Liu X.Q. DNA binding and bending by a chloroplast-encoded HU-like protein overexpressed in Escherichia coli. Plant Mol. Biol. 34 (1997) 339-343
12. Ram E.V., Naik R., Ganguli M., and Habib S. DNA organization by the apicoplast-targeted bacterial histone-like protein of Plasmodium falciparum. Nucleic Acids Res. 36 (2008) 5061-5073
13. Singh D., Chaubey S., and Habib S. Replication of the Plasmodium falciparum apicoplast DNA initiates within the inverted repeat region. Mol. Biochem. Parasitol. 126 (2003) 9-14
14. Huisman O., Faelen M., Girard D., Jaffe A., Toussaint A., and Rouviere-Yaniv J. Multiple defects in Escherichia coli mutants lacking HU protein. J. Bacteriol. 171 (1989) 3704-3712
15. Dessens J.T., Beetsma A.L., Dimopoulos G., Wengelnik K., Crisanti A., Kafatos F.C., and Sinden R.E. CTRP is essential for mosquito infection by malaria ookinetes. EMBO J. 18 (1999) 6221-6227
16. Hirai M., et al. Male fertility of malaria parasites is determined by GCS1, a plant-type reproduction factor. Curr. Biol. 18 (2008) 607-613
17. Wada M., Kano Y., Ogawa T., Okazaki T., and Imamoto F. Construction and characterization of the deletion mutant of hupA and hupB genes in Escherichia coli. J. Mol. Biol. 204 (1988) 581-591
18. Patankar S., Munasinghe A., Shoaibi A., Cummings L.M., and Wirth D.F. Serial analysis of gene expression in Plasmodium falciparum reveals the global expression profile of erythrocytic stages and the presence of anti-sense transcripts in the malarial parasite. Mol. Biol. Cell 12 (2001) 3114-3125
19. Dri A.M., Rouviere-Yaniv J., and Moreau P.L. Inhibition of cell division in hupA hupB mutant bacteria lacking HU protein. J. Bacteriol. 173 (1991) 2852-2863
20. Guo L., Katayama T., Seyama Y., Sekimizu K., and Miki T. Isolation and characterization of novel cold-sensitive dnaA mutants of Escherichia coli. FEMS Microbiol. Lett. 176 (1999) 357-366