Trials for development of once-a-month injectable, hormonal male contraceptive using dienogest plus testosterone undecanoate: dose standardization, efficacy and reversibility studies in rats

Contraception

Volumn 79, Issue 6, 2009, Pages 488-497

  Misro, Man M ^a   Chaki, Shankar P ^a   Kaushik, Mahesh C ^a   Nandan, Deoki ^a  

^a NATIONAL INSTITUTE OF HEALTH AND FAMILY WELFARE   (India)

Author keywords

Dienogest; Epididymal sperm; Fertility test; Spermatogenic arrest; Testosterone undecanoate; Toxicity

Indexed keywords

ALPHA GLUCOSIDASE; DIENOGEST; FOLLITROPIN; LUTEINIZING HORMONE; TESTOSTERONE UNDECANOATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE CALCULATION; DRUG MIXTURE; EPIDIDYMIS; FOLLITROPIN BLOOD LEVEL; HISTOLOGY; HORMONAL CONTRACEPTION; LITTER SIZE; LIVER TOXICITY; LUTEINIZING HORMONE BLOOD LEVEL; MALE; MALE FERTILITY; NONHUMAN; PROSTATE; RAT; RETE TESTIS; SEMINAL VESICLE; SPERMATOGENESIS; SPERMATOZOON COUNT; STANDARDIZATION;

ALPHA-GLUCOSIDASES; ANIMALS; APOPTOSIS; BLOOD CHEMICAL ANALYSIS; CONTRACEPTION; CONTRACEPTIVE AGENTS, MALE; EPIDIDYMIS; FEMALE; HISTOCYTOCHEMISTRY; IN SITU NICK-END LABELING; INJECTIONS, INTRAVENOUS; LITTER SIZE; MALE; NANDROLONE; PREGNANCY; RATS; RATS, WISTAR; SPERM COUNT; SPERMATOGENESIS; TESTIS; TESTOSTERONE;

EID: 67349231356     PISSN: 00107824     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.contraception.2009.01.003     Document Type: Article

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