Oral desogestrel with testosterone pellets induces consistent suppression of spermatogenesis to azoospermia in both Caucasian and Chinese men

Human Reproduction

Volumn 17, Issue 6, 2002, Pages 1490-1501

  Kinniburgh, D ^a   Zhu, H ^b   Cheng, L ^b   Kicman, A T ^c   Baird, D T ^a   Anderson, R A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b Shanghai Institute of Family Planning Technical Instruction   (China)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Desogestrel; Male contraception; Progestogen; Spermatogenesis; Testosterone

Indexed keywords

DESOGESTREL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TESTOSTERONE; ANTISPERMATOGENIC AGENT; EPITESTOSTERONE; GONADOTROPIN; INHIBIN; LIPID; SEX HORMONE BINDING GLOBULIN;

ADULT; ARTICLE; AZOOSPERMIA; BODY WEIGHT DISORDER; CAUCASIAN; CHINESE; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG PELLET; DRUG WITHDRAWAL; GEOGRAPHIC DISTRIBUTION; HORMONAL CONTRACEPTION; HORMONE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PREVALENCE; PROSPECTIVE STUDY; RACE DIFFERENCE; RANDOMIZED CONTROLLED TRIAL; SEMEN ANALYSIS; SPERMATOGENESIS; WEIGHT GAIN; AFFECT; ASIAN; BLOOD; CHEMICALLY INDUCED DISORDER; DRUG IMPLANT; METABOLISM; MULTICENTER STUDY; OLIGOSPERMIA; ORAL DRUG ADMINISTRATION; SPERMATOZOON COUNT; URINE;

ADMINISTRATION, ORAL; ADULT; AFFECT; ASIAN CONTINENTAL ANCESTRY GROUP; DESOGESTREL; DRUG IMPLANTS; EPITESTOSTERONE; EUROPEAN CONTINENTAL ANCESTRY GROUP; GONADOTROPINS, PITUITARY; HUMANS; INHIBINS; LIPIDS; MALE; OLIGOSPERMIA; PROSPECTIVE STUDIES; SEX HORMONE-BINDING GLOBULIN; SPERM COUNT; SPERMATOGENESIS; SPERMATOGENESIS-BLOCKING AGENTS; TESTOSTERONE;

EID: 0035988399     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/17.6.1490     Document Type: Article

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