Overexpression of the transcription factor Hand1 causes predisposition towards arrhythmia in mice

Journal of Molecular and Cellular Cardiology

Volumn 47, Issue 1, 2009, Pages 133-141

  Breckenridge, Ross A ^a,b   Zuberi, Zia ^b   Gomes, John ^b   Orford, Robert ^a   Dupays, Laurent ^a   Felkin, Leanne E ^c   Clark, James E ^d   Magee, Anthony I ^f   Ehler, Elisabeth ^e   Birks, Emma J ^c,g   Barton, Paul J R ^c   Tinker, Andrew ^b   Mohun, Timothy J ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

^g HAREFIELD HOSPITAL   (United Kingdom)

Author keywords

Arrhythmogenesis; Connexin43; Hand1; Heart; Heart failure; Tet on; Transcription factor; Transgenic

Indexed keywords

BETA CATENIN; CONNEXIN 43; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HAND1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DISEASE PREDISPOSITION; HEART ARRHYTHMIA; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE TACHYCARDIA; HUMAN; HUMAN TISSUE; LIFE EXPECTANCY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; ARRHYTHMIAS, CARDIAC; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARDIOMEGALY; ELECTROPHYSIOLOGY; HEART FAILURE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, TRANSGENIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

MUS;

EID: 67349229548     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.04.007     Document Type: Article

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