Antisocial and borderline personality disorder symptomatologies are associated with decreased prepulse inhibition: The importance of optimal experimental parameters

Personality and Individual Differences

Volumn 47, Issue 5, 2009, Pages 439-443

  Franklin, Joseph C ^a   Heilbron, Nicole ^a   Guerry, John D ^a   Bowker, Kelly B ^b   Blumenthal, Terry D ^b  

^a University of North Carolina at Chapel Hill   (United States)

^b WAKE FOREST UNIVERSITY   (United States)

Author keywords

Alcohol dependence; Antisocial personality disorder; Blink; Borderline personality disorder; PPI; Prepulse inhibition; Signal to noise ratio; Startle

Indexed keywords

EID: 67349223267     PISSN: 01918869     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.paid.2009.04.016     Document Type: Article

References (40)

1. American Psychiatric Association. (1987). Diagnostic and statistical manual of mental disorders (3rd ed., rev.). Washington, DC: American Psychiatric Association.
2. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. (1994), American Psychiatric Association, Washington, DC
3. Blair J., Mitchell D., and Blair K. The psychopath: Emotion and the brain (2005), Blackwell Publishing, Malden, MA
4. Blumenthal T.D. Short lead interval modification. In: Dawson M.E., Schell A.M., and Boehmelt A.H. (Eds). Startle modification: Implications for neuroscience, cognitive science, and clinical science (1999), Cambridge University Press, Cambridge, UK 51-71
5. Blumenthal T.D., Cuthbert B.N., Filion D.L., Hackley S., Lipp O.V., and van Boxtel A. Committee report: Guidelines for human startle eyeblink electromyographic studies. Psychophysiology 42 (2005) 1-15
6. Blumenthal T.D., Elden A., and Flaten M.A. A comparison of several methods used to quantify prepulse inhibition of eyeblink responding. Psychophysiology 41 (2004) 326-332
7. Blumenthal T.D., and Franklin J.C. The startle eyeblink response. In: Harmon-Jones E., and Beer J.S. (Eds). Methods in social neuroscience (2009), Guilford Press, New York, NY 92-117
8. Blumenthal T.D., Noto J.V., Fox M.A., and Franklin J.C. Background noise decreased both prepulse elicitation and inhibition of acoustic startle blink responding. Biological Psychology 72 (2006) 173-179
9. Braff D.L., and Freedman R. The importance of endophenotypes in studies of the genetics of schizophrenia. In: Davis K.L., Charney D., Coyle J.T., and Nemeroff C. (Eds). Neuropsychopharmacology: The fifth generation of progress (2002), Lippincott, Williams & Wilkins, Baltimore, MD 703-716
10. Braff D.L., Geyer M.A., and Swerdlow N.A. Human studies of prepulse inhibition of startle: Normal subjects, patient groups, and pharmacological studies. Psychopharmacology 156 (2001) 234-258
11. Cadenhead K.S., Swerdlow N.R., Shafer K.M., Diaz M., and Braff D.L. Modulation of the startle response and startle laterality in relatives of schizophrenia patients and in subjects with schizotypal personality disorder: Evidence of inhibitory deficits. American Journal of Psychiatry 157 (2000) 1660-1668
12. Campbell L.E., Hughes M., Budd T.W., Cooper G., Fulham W.R., Karayanidis F., et al. European Journal of Neuroscience 26 (2007) 2327-2333
13. Castellanos F.X., Fine E.J., Kaysen D., Marsh W.L., Rapoport J.L., and Hallett M. Sensorimotor gating in boys with Tourette's syndrome and ADHD: Preliminary results. Biological Psychiatry 39 (1996) 33-41
14. Clark L.A. Assessment and diagnosis of personality disorder: Perennial issues and emerging conceptualization. Annual Review of Psychology 58 (2007) 227-258
15. Davis R.D., Wenger A., and Guzman A. Validation of the MCMI-III. In: Millon T. (Ed). The Millon inventories: Clinical and personality assessment (1997), Guilford Press, New York, NY, US 327-359
16. Duncan E.J., Bollini A.M., Lewison B., Keyes M., Jovanovic T., Gaytan O., et al. Medication status affects the relationship of symptoms to prepulse inhibition of acoustic startle in schizophrenia. Psychiatry Research 145 (2006) 137-145
17. Franklin J.C., Bowker K.B., and Blumenthal T.D. Anxiety and prepulse inhibition of acoustic startle in a normative sample: The importance of signal-to-noise ratio. Personality and Individual Differences 46 (2009) 369-373
18. Franklin J.C., Moretti N.A., and Blumenthal T.D. Impact of stimulus signal-to-noise ratio on prepulse inhibition of acoustic startle. Psychophysiology 44 (2007) 339-342
19. Grillon C., Morgan C.A., Southwick S.M., Davis M., and Charney D.S. Baseline startle amplitude and prepulse inhibition in Vietnam veterans with posttraumatic stress disorder. Psychiatry Research 64 (1996) 169-178
20. Grillon C., Sinha R., Ameli R., and O'Malley S.S. Effects of alcohol on baseline startle and prepulse inhibition in young men at risk for alcoholism and/or anxiety disorders. Journal of Studies on Alcohol 61 (2000) 46-54
21. Grootens K.P., van Luijtelaar G., Miller C., Smits T., Hummelen J.W., Buitelaar J.K., et al. Increased P50 gating but intact prepulse inhibition in borderline personality disorder. The Journal of Neuropsychiatry and Clinical Neurosciences 20 (2008) 348-356
22. Herpertz S.C., and Koetting K. Startle response in inpatients with borderline personality disorder vs. healthy control. Journal of Neural Transmission 112 (2005) 1097-1106
23. Hoenig K., Hochrein A., Quednow B.B., Maier W., and Wagner M. Impaired prepulse inhibition of acoustic startle in obsessive-compulsive disorder. Biological Psychiatry 57 (2005) 1153-1158
24. Hutchinson K.E., MGeary J., Wooden A., Blumenthal T.D., and Ito T. Startle magnitude and prepulse inhibition: Effects of alcohol and attention. Psychopharmacology 167 (2003) 235-241
25. Johnson P.A., Hurley R.A., Benkelfat C., Herpertz S.C., and Taber K.H. Understanding emotion regulation in borderline personality disorder: Contributions of neuroimaging. Journal of Neuropsychiatry and Clinical Neurosciences 15 (2003) 397-402
26. Keedwell P.A., Kumari V., Poon L., Marshall E.J., and Checkley S.A. Information processing deficits in withdrawing alcoholics. Addiction Biology 6 (2001) 239
27. Krueger R.F., Markon K.E., Patrick C.J., Benning S.D., and Kramer M.D. Linking antisocial behavior, substance use, and personality: An integrative quantitative model of the adult externalizing spectrum. Journal of Abnormal Psychology 116 (2007) 645-666
28. Kumari V., Antonova E., and Geyer M.A. Prepulse inhibition and "psychosis-proneness" in healthy individuals: An fMRI study. European Psychiatry 23 (2008) 274-280
29. Kumari V., Das M., Hodgins S., Zachariah E., Barkataki I., Howlett M., et al. Association between violent behavior and impaired prepulse inhibition of the startle response in antisocial personality disorder and schizophrenia. Behavioural Brain Research 158 (2005) 159-166
30. Linehan M.M. Cognitive behavioral treatment of borderline personality disorder (1993), Guilford Press, New York
31. Ludewig S., Geyer M.A., Ramseier M., Vollenweider F.X., Rechsteiner E., and Cattapan-Ludewig K. Information-processing deficits and cognitive dysfunction in panic disorder. Journal of Psychiatry and Neuroscience 30 (2005) 37-43
32. MacCallum R.C., Zhang S., Preacher K.J., and Rucker D.D. On the practice of dichotomization of quantitative variables. Psychological Methods 7 (2002) 19-40
33. McCann J.T., Flens J.R., Campagna V., Collman P., Lazzaro T., and Connor E. The MCMI-III in child custody evaluations: A normative study. Journal of Forensic Psychology Practice 1 (2001) 27-44
34. Millon T., Davis R.D., and Millon C. The Millon clinical multiaxial inventory-III manual (1996), National Computer System, Minnetonka, MN
35. Patrick C.J., Bradley M.M., and Lang P.J. Emotion in the criminal psychopath: Startle reflex modulation. Journal of Abnormal Psychology 102 (1993) 82-92
36. Strack S. Essentials of Millon inventories assessment (1999), John Wiley & Sons, Inc., Hobken, NJ, US
37. Strack S. Combined use of the PACL and MCMI-III to assess normal range personality styles. In: Craig R.J. (Ed). New directions in interpreting the Millon Clinical Multiaxial Inventory-III (2005), John Wiley & Sons, Inc., Hoboken, NJ, US 94-128
38. Stredny R.V., Archer R.P., and Mason J.A. MMPI-2 and MCMI-III characteristics of parental competency examinees. Journal of Personality Assessment 87 (2006) 113-115
39. Swerdlow N.R., Braff D.L., and Geyer M.A. Animal models of deficient sensorimotor gating: What we know, what we think we know, and what we hope to know soon. Behavioural Pharmacology 11 (2000) 185-204
40. Swerdlow N.R., Geyer M.A., and Braff D.L. Neural circuit regulation of prepulse inhibition of startle in the rat: Current knowledge and future challenges. Psychopharmacology 156 (2001) 194-215