Effects of the β-amino acid antagonist TAG on thalamocortical inhibition

Neuropharmacology

Volumn 56, Issue 8, 2009, Pages 1097-1105

  Mathers, David A ^a   McCarthy, Sarah M ^a   Cooke, James E ^a   Ghavanini, Ahmad A ^a   Puil, Ernest ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

GABAA receptor; Glycine receptor; IPSC; Strychnine; TAG; Thalamus

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4; 6 AMINOMETHYL 3 METHYL 4H 1,2,4 BENZOTHIADIAZINE 1,1 DIOXIDE; BETA AMINO ACID; BETA AMINO ACID ANTAGONIST; BICUCULLINE; GLYCINE; GLYCINE RECEPTOR; STRYCHNINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; INHIBITORY POSTSYNAPTIC POTENTIAL; MEDIAL LEMNISCUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RECEPTOR UPREGULATION; SYNAPTIC INHIBITION; THALAMOCORTICAL TRACT;

ANIMALS; BENZOTHIADIAZINES; BETA-ALANINE; BICUCULLINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCINE; INHIBITORY POSTSYNAPTIC POTENTIALS; KYNURENIC ACID; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; PROTEIN SUBUNITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; RECEPTORS, GLYCINE; STRYCHNINE; TAURINE; THALAMIC NUCLEI;

EID: 67349213969     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2009.03.008     Document Type: Article

References (38)

1. Bamji S.X., Rico B., Kimes N., and Reichart L.F. BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin-β-catenin interactions. Journal of Cell Biology 174 (2006) 289-299
2. Billard J.M., and Batini C. Decreased sensitivity of cerebellar nuclei neurons to GABA and taurine: effects of long-term inferior olive destruction in the rat. Neuroscience Research 9 (1991) 246-256
3. Curtis D.R., Leah J.D., and Peet M.J. Lack of specificity of a 'taurine-antagonist'. Brain Research 244 (1982) 198-199
4. Dumoulin A., Rostaing P., Bedet C., Levi S., Isambert M.F., Henry J.P., Triller A., and Gasnier B. Presence of the vesicular inhibitory amino acid transporter in GABAergic and glycinergic terminal boutons. Journal of Cell Science 112 (1999) 811-823
5. Dumoulin A., Triller A., and Dieudonne S. IPSC kinetics at identified GABAergic and mixed GABAergic and glycinergic synapses onto cerebellar Golgi cells. Journal of Neuroscience 21 (2001) 6045-6057
6. Farrar S.J., Whiting P.J., Bonnert T.P., and McKernan R.M. Stoichiometry of a ligand-gated ion channel determined by fluorescence energy transfer. Journal of Biological Chemistry 274 (1999) 10100-10104
7. Frosini M., Sesti C., Dragoni S., Valoti M., Palmi M., Dixon H.B.F., Machetti F., and Sgaragli G. Interactions of taurine and structurally related analogues with the GABAergic system and taurine binding sites of rabbit brain. British Journal of Pharmacology 138 (2003) 1163-1171
8. Ghavanini A.A., Mathers D.A., and Puil E. Glycinergic inhibition in thalamus revealed by synaptic receptor blockade. Neuropharmacology 49 (2005) 338-349
9. Ghavanini A.A., Mathers D.A., Kim H.S., and Puil E. Distinctive glycinergic currents with fast and slow kinetics in thalamus. Journal of Neurophysiology 95 (2006) 3438-3448
10. Girard Y., Atkinson J.G., Haubrich D.R., Williams M., and Yarbrough G.G. Aminomethyl-1,2,4-benzothiadiazines as potential analogues of γ-aminobutyric acid. Unexpected discovery of a taurine antagonist. Journal of Medicinal Chemistry 25 (1982) 113-116
11. Han N.L., Haddrill J.L., and Lynch J.W. Characterization of a glycine receptor domain that controls the binding and gating mechanisms of the β-amino acid agonist, taurine. Journal of Neurochemistry 79 (2001) 636-647
12. Harris R.M. Morphology of physiologically identified thalamocortical relay neurons in the rat ventrobasal thalamus. Journal of Comparative Neurology 251 (1986) 491-505
13. Hussy N., Deleuze C., Pantaloni A., Desarmenien M.G., and Moos F. Agonist action of taurine on glycine receptors in rat supraoptic magnocellular neurons: possible role in osmoregulation. Journal of Physiology 502 (1997) 609-621
14. A receptor mediates tonic inhibition in thalamic VB neurons. Journal of Neurophysiology 94 (2005) 4491-4501
15. A receptors in the thalamus. Journal of Neuroscience 28 (2008) 106-115
16. Jiang Z., Krnjević K., Wang F., and Yeh J.H. Taurine activates strychnine-sensitive glycine receptors in neurons freshly isolated from nucleus accumbens of young rats. Journal of Neurophysiology 91 (2004) 248-257
17. Jonas P., Bischofberger J., and Sandkuhler J. Corelease of two fast neurotransmitters at a central synapse. Science 281 (1998) 360-361
18. 2S receptors. Journal of General Physiology 131 (2008) 163-181
19. 2 subunits. Neuroscience 109 (2002) 733-743
20. Lewin L., Rassin D.K., and Sellstrom A. Net taurine transport and its inhibition by a taurine antagonist. Neurochemical Research 19 (1994) 347-352
21. Lu T., Rubio M.E., and Trussell L.O. Glycinergic transmission shaped by the corelease of GABA in a mammalian auditory synapse. Neuron 57 (2008) 524-535
22. Magistretti J., Mantegazza M., de Curtis M., and Wanke E. Modalities of distortion of physiological voltage signals by patch-clamp amplifiers: a modeling study. Biophysical Journal 74 (1998) 831-842
23. Martin G.E., Bendesky R.J., and Williams W. Further evidence for selective antagonism of taurine by 6-aminomethyl-3-methyl-4H-1,2,4-benzothiadiazine-1,1-dioxide. Brain Research 299 (1981) 530-535
24. Mathers D.A. Effects of the benzothiadiazine TAG on channel activation at mammalian glycine receptors. Neuroscience Letters 149 (1993) 23-26
25. A receptors in neocortex. Neuropharmacology 52 (2007) 1160-1168
26. McCool B.A., and Botting S.K. Characterization of strychnine-sensitive glycine receptors in acutely isolated adult rat basolateral amygdala neurons. Brain Research 859 (2000) 341-351
27. Mori M., Gahwiler B.H., and Gerber U. β-Alanine and taurine as endogenous agonists at glycine receptors in rat hippocampus in vitro. Journal of Physiology 539 (2002) 191-200
28. Okamoto K., Kimura H., and Sakai Y. Evidence for taurine as an inhibitory neurotransmitter in cerebellar stellate interneurons: selective antagonism by TAG (6-aminomethyl-3-methyl-4H,1,2,4-benzothiadiazine-1,1-dioxide). Brain Research 265 (1983) 163-168
29. Ottersen O.P., Madsen S., Storm-Mathisen J., Somogyi P., Scopsi L., and Larsson L.I. Immunocytochemical evidence suggests that taurine is colocalized with GABA in the Purkinje cell terminals, but that the stellate cell terminals predominantly contain GABA: a light- and electronmicroscopic study of the rat cerebellum. Experimental Brain Research 72 (1988) 407-416
30. Padjen A.L., Mitsoglou G.M., and Hassessian H. Further evidence in support of taurine as a mediator of synaptic transmission in the frog spinal cord. Brain Research 488 (1989) 288-296
31. 3H taurine accumulation in the rat retina, pituitary, and brain. Glia 37 (2002) 153-168
32. Singer J.H., and Berger A.J. Contribution of single-channel properties to the time course and amplitude variance of quantal glycine currents recorded in rat motoneurons. Journal of Neurophysiology 81 (1999) 1608-1616
33. Sohal V.S., Pangratz-Fuehrer S., Rudolph U., and Huguenard J.R. Intrinsic and synaptic dynamics interact to generate emergent patterns of rhythmic bursting in thalamocortical neurons. Journal of Neuroscience 26 (2006) 4247-4255
34. Takahashi T., Momiyama A., Hirai K., Hishinuma F., and Akagi H. Functional correlation of fetal and adult forms of glycine receptors with developmental changes in inhibitory synaptic receptor channels. Neuron 9 (1992) 1155-1161
35. Turecek R., and Trussell L.O. Presynaptic glycine receptors enhance transmitter release at a mammalian central synapse. Nature 411 (2001) 587-590
36. 1 subunit of the inhibitory glycine receptor. Journal of Neurochemistry 73 (1999) 2158-2166
37. A and glycine receptors by β-alanine: inverse modulation by progesterone and 5α-pregnan-3α-ol-20-one. European Journal of Pharmacology 246 (1993) 239-246
38. Yarbrough G.G., Singh D.K., and Taylor D.A. Neuropharmacological characterization of a taurine antagonist. Journal of Pharmacology and Experimental Therapeutics 219 (1981) 604-613