The association of metal ion exposure with α-synuclein-like immunoreactivity in the central nervous system of fish, Catostomus commersoni

Aquatic Toxicology

Volumn 92, Issue 4, 2009, Pages 258-263

  Boudreau, Heather S ^a   Krol, Karmen M ^b   Eibl, Joseph K ^b   Williams, Linda D ^a   Rossiter, John P ^a   Palace, Vincent P ^c   Ross, Gregory M ^b  

^a QUEEN S UNIVERSITY   (Canada)

^b NORTHERN ONTARIO SCHOOL OF MEDICINE   (Canada)

^c FISHERIES AND OCEANS CANADA   (Canada)

Author keywords

Environmental toxicity; Metal ions; Parkinson's disease; Protein aggregation

Indexed keywords

ALPHA SYNUCLEIN; METAL ION; METALLOTHIONEIN;

CATION; CYPRINID; ECOTOXICOLOGY; ENVIRONMENTAL RISK; IMMUNE SYSTEM; NERVOUS SYSTEM DISORDER; PATHOLOGY; POLLUTION EXPOSURE; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANADA; CENTRAL NERVOUS SYSTEM; FISH; IMMUNOREACTIVITY; LONG TERM EXPOSURE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; WATER CONTAMINATION;

ALPHA-SYNUCLEIN; ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM; CYPRINIFORMES; IMMUNOHISTOCHEMISTRY; IONS; LIVER; METALS; PROTEIN BINDING; WATER POLLUTANTS, CHEMICAL;

CANADA; NORTH AMERICA; ONTARIO [CANADA]; RED LAKE [ONTARIO];

CATOSTOMUS COMMERSONI;

EID: 67349207088     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2009.02.011     Document Type: Article

References (37)

1. Binolfi A., Rasia R.M., Bertoncini C.W., Ceolin M., Zweckstetter M., Griesinger C., Jovin T.M., and Fernández C.O. Interaction of α-synuclein with divalent metal ions reveals key differences: a link between structure, binding specificity and fibrillation enhancement. J. Am. Chem. Soc. 128 (2006) 9893-9901
2. Binolfi A., Lamberto G.R., Duran R., Quintanar L., Bertoncini C.W., Souza J.M., Cervenansky C., Zweckstetter M., Griesinger C., and Frenandez C.O. Site-specific interactions of Cu(II) with α and β-synuclein: bridging the molecular gap between metal binding and aggregation. J. Am. Chem. Soc. 130 (2008) 11801-11812
3. Bush A.I. Metals and neuroscience. Curr. Opin. Chem. Biol. 4 (2000) 184-191
4. Cabin D.E., Shimazu K., Murphy D., Cole N.B., Gottschalk W., McIlwain K.L., Orrison B., Chen A., Ellis C.E., Paylor R., Lu B., and Nussbaum R.L. Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein. J. Neurosci. 22 (2002) 8797-8807
5. Chen Y., and Harvey H.H. Growth, abundance, and food supply of white sucker. Trans. Am. Fish Soc. 124 (1995) 262-271
6. Conway K.A., Harper J.D., and Lansbury P.T. Fibrils formed in vitro from alpha synuclein and two mutant forms linked to Parkinson's disease are typical β-amyloid. Biochemistry 30 (2000) 2552-2563
7. Cousins R.J. Absorption, transport, and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin. Physiol. Rev. 65 (1985) 238-309
8. Di Monte D.A., Lavasani M., and Manning-Bog A.B. Environmental factors in Parkinson's disease. Neurotoxicology 23 (2002) 487-502
9. Duffy P.E., and Tennyson V.M. Phase and electron microscopic observations of Lewy bodies and melanin granules in the substantia nigra and Locus caeruleus in Parkinson's disease. J. Neuropathol. Exp. Neurol. 24 (1965) 398-414
10. Gaeta A., and Hider R.C. The crucial role of metal ions in neurodegeneration: the basis for a promising therapeautic strategy. Br. J. Pharm. 146 (2005) 1041-1059
11. Gorell J.M., Johnson C.C., Rybicki B.A., Peterson E.L., Kortsha G.X., Brown G.G., and Richardson R.J. Occupational exposures to metals as risk factors for Parkinson's disease. Neurology 48 (1997) 650-658
12. Gorell J.M., Johnson C.C., Rybicki B.A., Peterson E.L., Kortsha G.X., Brown G.G., and Richardson R.J. Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease. Neurotoxicology 20 (1999) 239-247
13. Hamilton S.J., and Mehrle P.M. Metallothionein in fish: review of its importance in assessing stress from metal contaminants. Trans. Am. Fish Soc. 115 (1986) 596-609
14. Haux C., and Förlin L. Biochemical methods for detecting effects of contaminants on fish. Ambio 17 (1988) 376-380
15. Hogstrand C., and Haux C. Binding and detoxification of heavy metals in lower vertebrates with special reference to metallothionein. Comp. Physiol. Biochem. 100C (1991) 137-141
16. Hogstrand C., Lithner G., and Haux C. The importance of metallothionein for the accumulation of copper, zinc, and cadmium in environmentally exposed perch, Perca fluviatilis. Pharmacol. Toxicol. 68 (1992) 492-501
17. Klaverkamp J.F., Wautier K., and Baron C.L. A modified mercury saturation assay for measuring metallothionein. Aquat. Toxicol. 50 (2000) 13-25
18. Maldonado T.A., Jones R.E., and Norris D.O. Distribution of beta-amyloid and amyloid precursor protein in the brain of spawning (senescent) salmon: a natural, brain-aging model. Brain Res. 858 (2000) 237-251
19. Maldonado T.A., Jones R.E., and Norris D.O. Intraneuronal amyloid precursor protein (APP) and appearance of extracellular beta-amyloid peptide (abeta) in the brain of aging kokanee salmon. J. Neurobiol. 53 (2002) 11-20
20. Maldonado T.A., Jones R.E., and Norris D.O. Timing of neurodegeneration and beta-amyloid (Abeta) peptide deposition in the brain of aging kokanee salmon. J. Neurobiol. 53 (2002) 21-35
21. Maroteaux L., Campanelli J.T., and Scheller R.H. Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal. J. Neurosci. 8 (1988) 2804-2815
22. Okazaki H., Lipkin L.E., and Aronson S.M. Diffuse intracytoplasmic ganglionic inclusions (Lewy type) associated with progressive dementia and quadriparesis in flexion. J. Neuropathol. Exp. Neurol. 20 (1961) 237-244
23. Paik S.R., Shin H.J., Lee J.H., Chang C.S., and Kim J. Copper(II)-induced self-oligomerization of alpha-synuclein. Biochem. J. 340 (1999) 821-828
24. Palace V.P., Baron C.L., Evans R.E., Wautier K., Werner J., Kollar S., and Klaverkamp J.F. Metals, metalloids and metallothionein in tissues of fish from a Canadian freshwater system receiving gold mine effluents. J. Phys. IV France 107 (2003) 1009-1012
25. Perez R.G., and Hastings T.G. Could a loss of α-synuclein function put dopaminergic neurons at risk?. J. Neurochem. 89 (2004) 1318-1324
26. Perez R.G., Waymore J.C., Lin E., Liu J.J., Guo F., and Zigmond M.J. A role for α-synuclein in the regulation of dopamine synthesis. J. Neurosci. 22 (2002) 3090-3099
27. Powers K.M., Smith-Weller T., Franklin G.M., Longstreth Jr. W.T., Swanson P.D., and Checkoway H. Parkinson's disease risks associated with dietary iron, maganese, and other nutrient intake. Neurology 60 (2003) 1761-1766
28. Rasia R.M., Bertoncini C.W., Marsh D., Hoyer W., Cherny D., Zweckstetter M., Griesinger C., Jovin T.M., and Fernández C.O. Structural characterization of copper(II) binding to α-synuclein: insights into the bioinorganic chemistry of Parkinson's disease. PNAS 102 (2005) 4294-4299
29. Ryan R.W., Post J.I., Solc M., Hodson P.V., and Ross G.M. Catecholaminergic neuronal degeneration in rainbow trout assessed by skin color change: a model system for identification of environmental risk factors. Neurotoxicology 23 (2002) 545-551
30. Rybicki B.A., Johnson C.C., Uman J., and Gorell J.M. Parkinson's disease mortality and the industrial use of heavy metals in Michigan. Mov. Disord. 8 (1993) 87-92
31. Sayre L.M., Moreira P.A., Smith M.A., and Perry G. Metal ions and oxidative protein modification in neurological disease. Ann. Ist. Super Sanità 41 (2005) 143-164
32. Tabner B.J., Turnbull S., El-Agnaf O.M.A., and Allsop D. Formation of hydrogen peroxide and hydroxyl radiacals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease. Free Radic. Biol. Med. 32 (2002) 1076-1083
33. Uversky V.N., Li J., and Fink A.L. Metal-triggered structural transformations, aggregation, and fibrillation of human α-synuclein. J. Biol. Chem. 276 (2001) 44284-44296
34. Uversky V.N., Li J., Bower K., and Fink A.L. Synergistic effects of pesticides and metals on the fibrillation of alpha-synuclein: implications for Parkinson's disease. Neurotoxicology 23 (2002) 527-536
35. Weinreb P.H., Zhen W., Poon A., Conway K.A., and Lansbury Jr. P.T. NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. Biochemistry 35 (1996) 13709-13715
36. Werner J., Palace V., Shiu R., and Yarmil A. A real-time PCR method for the quantification of the two isoforms of metallothionein in lake trout (Salvelinus namaycush). Arch. Environ. Contam. Toxicol. 1 (2008) 84-91
37. Yu S., Ueda K., and Chan P. Alpha-synuclein and dopamine metabolism. Mol. Neurobiol. 31 (2005) 243-254