Tomato bushy stunt virus (TBSV), a versatile platform for polyvalent display of antigenic epitopes and vaccine design

Virology

Volumn 388, Issue 1, 2009, Pages 185-190

  Kumar, Shantanu ^a   Ochoa, Wendy ^a   Singh, Pratik ^a   Hsu, Catherine ^a   Schneemann, Anette ^a   Manchester, Marianne ^a   Olson, Mark ^b   Reddy, Vijay ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

Capsid display; Ricin vaccine; Tomato bushy stunt virus; Vaccine design; Virus like particles

Indexed keywords

CAPSID PROTEIN; RICIN A; RICIN ANTIBODY; RICIN ANTIGEN; UNCLASSIFIED DRUG; VACCINE; VIRUS VECTOR;

ADAPTIVE IMMUNITY; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DRUG DESIGN; ELECTRON MICROSCOPY; IMAGE RECONSTRUCTION; MOUSE; NONHUMAN; PLANT VIRUS; PRIORITY JOURNAL; TOMATO BUSHY STUNT VIRUS; VIRUS ASSEMBLY; VIRUS CAPSID; VIRUS LIKE AGENT;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS; CAPSID; CELL LINE; EPITOPES; INSECTS; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; RICIN; TOMBUSVIRUS; VACCINES;

HEXAPODA; MIRIDAE; MUS; TOMATO BUSHY STUNT VIRUS;

EID: 67349205091     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2009.02.051     Document Type: Article

References (26)

1. Bachmann M.F., Rohrer U.H., Kundig T.M., Burki K., Hengartner H., and Zinkernagel R.M. The influence of antigen organization on B cell responsiveness. Science 262 5138 (1993) 1448-1451
2. Baker T.S., Drak J., and Bina M. Reconstruction of the three-dimensional structure of simian virus 40 and visualization of the chromatin core. Proc. Natl. Acad. Sci. U.S.A. 85 2 (1988) 422-426
3. Baker T.S., Newcomb W.W., Olson N.H., Cowsert L.M., Olson C., and Brown J.C. Structures of bovine and human papillomaviruses. Analysis by cryoelectron microscopy and three-dimensional image reconstruction. Biophys. J. 60 6 (1991) 1445-1456
4. Baker T.S., Olson N.H., and Fuller S.D. Adding the third dimension to virus life cycles: three-dimensional reconstruction of icosahedral viruses from cryo-electron micrographs. Microbiol. Mol. Biol. Rev. 63 4 (1999) 862-922 table of contents
5. Chackerian B., Durfee M.R., and Schiller J.T. Virus-like display of a neo-self antigen reverses B cell anergy in a B cell receptor transgenic mouse model. J. Immunol. 180 9 (2008) 5816-5825
6. Chackerian B., Lowy D.R., and Schiller J.T. Induction of autoantibodies to mouse CCR5 with recombinant papillomavirus particles. Proc. Natl. Acad. Sci. U.S.A. 96 5 (1999) 2373-2378
7. Dintzis H.M., Dintzis R.Z., and Vogelstein B. Molecular determinants of immunogenicity: the immunon model of immune response. Proc. Natl. Acad. Sci. U.S.A. 73 10 (1976) 3671-3675
8. Fokine A., Bowman V.D., Battisti A.J., Li Q., Chipman P.R., Rao V.B., and Rossmann M.G. Cryo-electron microscopy study of bacteriophage T4 displaying anthrax toxin proteins. Virology 367 2 (2007) 422-427
9. Fuller S.D. The T=4 envelope of Sindbis virus is organized by interactions with a complementary T=3 capsid. Cell 48 6 (1987) 923-934
10. Harrison S.C., Olson A.J., Schutt C.E., Winkler F.K., and Bricogne G. Tomato bushy stunt virus at 2.9 Å resolution. Nature 276 (1978) 368-373
11. Ho S.N., Hunt H.D., Horton R.M., Pullen J.K., and Pease L.R. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77 1 (1989) 51-59
12. Hsu C., Singh P., Ochoa W., Manayani D.J., Manchester M., Schneemann A., and Reddy V.S. Characterization of polymorphism displayed by the coat protein mutants of tomato bushy stunt virus. Virology 349 1 (2006) 222-229
13. Jegerlehner A., Tissot A., Lechner F., Sebbel P., Erdmann I., Kundig T., Bachi T., Storni T., Jennings G., Pumpens P., Renner W.A., and Bachmann M.F. A molecular assembly system that renders antigens of choice highly repetitive for induction of protective B cell responses. Vaccine 20 25-26 (2002) 3104-3112
14. Joelson T., Akerblom L., Oxelfelt P., Strandberg B., Tomenius K., and Morris T.J. Presentation of a foreign peptide on the surface of tomato bushy stunt virus. J. Gen. Virol. 78 Pt 6 (1997) 1213-1217
15. Khor I.W., Lin T., Langedijk J.P., Johnson J.E., and Manchester M. Novel strategy for inhibiting viral entry by use of a cellular receptor-plant virus chimera. J. Virol. 76 9 (2002) 4412-4419
16. Li Q., Shivachandra S.B., Zhang Z., and Rao V.B. Assembly of the small outer capsid protein, Soc, on bacteriophage T4: a novel system for high density display of multiple large anthrax toxins and foreign proteins on phage capsid. J. Mol. Biol. 370 5 (2007) 1006-1019
17. Ludwig C., and Wagner R. Virus-like particles-universal molecular toolboxes. Curr. Opin. Biotechnol. 18 6 (2007) 537-545
18. Manayani D.J., Thomas D., Dryden K.A., Reddy V., Siladi M.E., Marlett J.M., Rainey G.J., Pique M.E., Scobie H.M., Yeager M., Young J.A., Manchester M., and Schneemann A. A viral nanoparticle with dual function as an anthrax antitoxin and vaccine. PLoS Pathog. 3 10 (2007) 1422-1431
19. Manchester M., and Singh P. Virus-based nanoparticles (VNPs): platform technologies for diagnostic imaging. Adv. Drug Deliv. Rev. 58 14 (2006) 1505-1522
20. Milich D.R., Chen M., Schodel F., Peterson D.L., Jones J.E., and Hughes J.L. Role of B cells in antigen presentation of the hepatitis B core. Proc. Natl. Acad. Sci. U.S.A. 94 26 (1997) 14648-14653
21. Olson A.J., Bricogne G., and Harrison S.C. Structure of tomato busy stunt virus IV. The virus particle at 2.9 A resolution. J. Mol. Biol. 171 1 (1983) 61-93
22. Peabody D.S., Manifold-Wheeler B., Medford A., Jordan S.K., do Carmo Caldeira J., and Chackerian B. Immunogenic display of diverse peptides on virus-like particles of RNA phage MS2. J. Mol. Biol. 380 1 (2008) 252-263
23. Pettersen E.F., Goddard T.D., Huang C.C., Couch G.S., Greenblatt D.M., Meng E.C., and Ferrin T.E. UCSF Chimera-a visualization system for exploratory research and analysis. J. Comput. Chem. 25 13 (2004) 1605-1612
24. Porta C., Spall V.E., Loveland J., Johnson J.E., Barker P.J., and Lomonossoff G.P. Development of cowpea mosaic virus as a high-yielding system for the presentation of foreign peptides. Virology 202 2 (1994) 949-955
25. Shivachandra S.B., Li Q., Peachman K.K., Matyas G.R., Leppla S.H., Alving C.R., Rao M., and Rao V.B. Multicomponent anthrax toxin display and delivery using bacteriophage T4. Vaccine 25 7 (2007) 1225-1235
26. Stockley P.G., Kirsh A.L., Chow E.P., Smart J.E., and Harrison S.C. Structure of turnip crinkle virus. III. Identification of a unique coat protein dimer. J. Mol. Biol. 191 4 (1986) 721-725