Postprandial changes in solubilizing capacity of human intestinal fluids for BCS class II drugs

Pharmaceutical Research

Volumn 26, Issue 6, 2009, Pages 1456-1466

  Clarysse, Sarah ^a   Psachoulias, Dimitrios ^b   Brouwers, Joachim ^a   Tack, Jan ^c   Annaert, Pieter ^a   Duchateau, Guus ^d   Reppas, Christos ^b   Augustijns, Patrick ^a  

^a DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^b UNIVERSITY OF ATHENS   (Greece)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^d UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

Author keywords

Human intestinal fluids; Poorly water soluble drugs; Postprandial; Simulated intestinal fluid; Solubilizing capacity

Indexed keywords

DANAZOL; DIAZEPAM; INDOMETACIN; KETOCONAZOLE; NIFEDIPINE;

ARTICLE; DRUG ABSORPTION; DRUG SOLUBILITY; DRUG STRUCTURE; FEMALE; FOOD COMPOSITION; FOOD INTAKE; HUMAN; HUMAN EXPERIMENT; INTESTINE FLUID; MALE; NORMAL HUMAN; NUTRITIONAL STATUS; PH; POSTPRANDIAL STATE; PRIORITY JOURNAL; SOLUBILIZATION;

DIET; DUODENUM; FEMALE; FOOD-DRUG INTERACTIONS; GASTROINTESTINAL CONTENTS; HUMANS; LINEAR MODELS; MALE; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; POSTPRANDIAL PERIOD; SOLUBILITY; TIME FACTORS;

EID: 67349204296     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9857-7     Document Type: Article

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