메뉴 건너뛰기




Volumn 13, Issue 2, 2008, Pages 143-155

Rapamycin conditionally inhibits Hsp90 but not Hsp70 mRNA translation in Drosophila: Implications for the mechanisms of Hsp mRNA translation

Author keywords

Heat shock; Hsp70; Hsp90; Rapamycin; Translation

Indexed keywords

HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; INITIATION FACTOR 4E BINDING PROTEIN; MESSENGER RNA; RAPAMYCIN; TARGET OF RAPAMYCIN KINASE;

EID: 67349200037     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-008-0024-6     Document Type: Article
Times cited : (10)

References (50)
  • 1
    • 9644275414 scopus 로고    scopus 로고
    • Translational Regulation of Hsp90 mRNA: AUG-proximal 5′¢ untranslated region elements essential for preferential heart shock translation
    • Ahmed R, Duncan RF (2004) Translational Regulation of Hsp90 mRNA: AUG-proximal 5′¢ untranslated region elements essential for preferential heart shock translation. J Biol Chem 279:49919-49930
    • (2004) J Biol Chem , vol.279 , pp. 49919-49930
    • Ahmed, R.1    Duncan, R.F.2
  • 3
    • 0030066934 scopus 로고    scopus 로고
    • Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation
    • Beretta L, Gingras A-C, Svitkin YV, Hall MN, Sonenberg N (1996) Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. EMBO J 15:658-664
    • (1996) EMBO J , vol.15 , pp. 658-664
    • Beretta, L.1    Gingras, A.-C.2    Svitkin, Y.V.3    Hall, M.N.4    Sonenberg, N.5
  • 4
    • 0037184089 scopus 로고    scopus 로고
    • Free poly(A) stimulates capped mRNA translation in vitro through the eIF4G-poly(A)-binding protein interaction
    • Borman AM, Michel YM, Malnou CE, Kean KM (2002) Free poly(A) stimulates capped mRNA translation in vitro through the eIF4G-poly(A)-binding protein interaction. J Biol Chem 277:36818-36824
    • (2002) J Biol Chem , vol.277 , pp. 36818-36824
    • Borman, A.M.1    Michel, Y.M.2    Malnou, C.E.3    Kean, K.M.4
  • 5
    • 0030598885 scopus 로고    scopus 로고
    • A signaling pathway to translational control
    • Brown EJ, Schreiber SL (1996) A signaling pathway to translational control. Cell 86:517-520
    • (1996) Cell , vol.86 , pp. 517-520
    • Brown, E.J.1    Schreiber, S.L.2
  • 6
    • 0032612322 scopus 로고    scopus 로고
    • Stress-induced activation of the heat-shock response: Cell and molecular biology of heat-shock factors
    • Cotto JJ, Morimoto RI (1999) Stress-induced activation of the heat-shock response: cell and molecular biology of heat-shock factors. Biochem Soc Symp 64:105-118
    • (1999) Biochem Soc Symp , vol.64 , pp. 105-118
    • Cotto, J.J.1    Morimoto, R.I.2
  • 7
    • 0025943409 scopus 로고
    • Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F
    • De Benedetti A, Joshi-Barve S, Rinker-Schaeffer C, Rhoads RE (1991) Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F. Mol Cell Biol 11:5435-5445
    • (1991) Mol Cell Biol , vol.11 , pp. 5435-5445
    • De Benedetti, A.1    Joshi-Barve, S.2    Rinker-Schaeffer, C.3    Rhoads, R.E.4
  • 8
    • 0028879416 scopus 로고
    • Cordycepin blocks recovery of non-heat shock mRNA translation following heat shock in Drosophila
    • Duncan RF (1995) Cordycepin blocks recovery of non-heat shock mRNA translation following heat shock in Drosophila. Eur J Biochem 233:784-792
    • (1995) Eur J Biochem , vol.233 , pp. 784-792
    • Duncan, R.F.1
  • 9
    • 0001892934 scopus 로고    scopus 로고
    • Translational control during heat shock
    • Hershey JWB, Mathews M, Sonenberg N (eds) Cold Spring Harbor Laboratory Press, New York
    • Duncan RF (1996) Translational control during heat shock. In: Hershey JWB, Mathews M, Sonenberg N (eds) Translational control. Cold Spring Harbor Laboratory Press, New York
    • (1996) Translational Control
    • Duncan, R.F.1
  • 10
    • 0021228666 scopus 로고
    • Heat-shock induced translational alterations in HeLa cells: Initiation factor modifications and the inhibition of translation
    • Duncan R, Hershey JWB (1984a) Heat-shock induced translational alterations in HeLa cells: initiation factor modifications and the inhibition of translation. J Biol Chem 259:11882-11889
    • (1984) J Biol Chem , vol.259 , pp. 11882-11889
    • Duncan, R.1    Hershey, J.W.B.2
  • 11
    • 0021418471 scopus 로고
    • Evaluation of isoelectric focusing running conditions during two-dimensional isoelectric focusing/sodium dodecyl sulfate-polyacrylamide gel electrophoresis: Variation of gel patterns with changing conditions and optimized isoelectric focusing conditions
    • Duncan R, Hershey JWB (1984b) Evaluation of isoelectric focusing running conditions during two-dimensional isoelectric focusing/sodium dodecyl sulfate-polyacrylamide gel electrophoresis: variation of gel patterns with changing conditions and optimized isoelectric focusing conditions. Anal Biochem 138:144-155
    • (1984) Anal Biochem , vol.138 , pp. 144-155
    • Duncan, R.1    Hershey, J.W.B.2
  • 12
    • 0033570071 scopus 로고    scopus 로고
    • Striking multiplicity of eIF4E-BP1 phosphorylated isoforms identified by 2D gel electrophoresis regulation by heat shock
    • Duncan RF, Song HJ (1999) Striking multiplicity of eIF4E-BP1 phosphorylated isoforms identified by 2D gel electrophoresis regulation by heat shock. Eur J Biochem 265:728-743
    • (1999) Eur J Biochem , vol.265 , pp. 728-743
    • Duncan, R.F.1    Song, H.J.2
  • 13
    • 0023124676 scopus 로고
    • Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control
    • Duncan R, Milburn SC, Hershey JWB (1987) Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. J Biol Chem 262:380-388
    • (1987) J Biol Chem , vol.262 , pp. 380-388
    • Duncan, R.1    Milburn, S.C.2    Hershey, J.W.B.3
  • 14
    • 0030934285 scopus 로고    scopus 로고
    • Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes
    • Fadden P, Haystead TA, Lawrence JC Jr (1997) Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes. J Biol Chem 272:10240-10247
    • (1997) J Biol Chem , vol.272 , pp. 10240-10247
    • Fadden, P.1    Haystead, T.A.2    Lawrence Jr., J.C.3
  • 15
    • 0036090023 scopus 로고    scopus 로고
    • Interplay between molecular chaperones and signaling pathways in survival of heat shock
    • Gabai VL, Sherman MY (2002) Interplay between molecular chaperones and signaling pathways in survival of heat shock. J Appl Physiol 92:1743-1748
    • (2002) J Appl Physiol , vol.92 , pp. 1743-1748
    • Gabai, V.L.1    Sherman, M.Y.2
  • 17
    • 0035312747 scopus 로고    scopus 로고
    • Regulation of translation initiation by FRAP/mTOR
    • Gingras AC, Raught B, Sonenberg N (2001a) Regulation of translation initiation by FRAP/mTOR. Genes Dev 15:807-826
    • (2001) Genes Dev , vol.15 , pp. 807-826
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 20
    • 0030832026 scopus 로고    scopus 로고
    • EIF4G dramatically enhances the binding of eIF4E to the mRNA 5′¢-cap structure
    • Haghihat A, Sonenberg N (1997) eIF4G dramatically enhances the binding of eIF4E to the mRNA 5′¢-cap structure. J Biol Chem 272:21677-21680
    • (1997) J Biol Chem , vol.272 , pp. 21677-21680
    • Haghihat, A.1    Sonenberg, N.2
  • 22
    • 0029955331 scopus 로고    scopus 로고
    • Sequence and structure determinants of Drosophila Hsp70 mRNA translation: 5′¢-UTR secondary structure specifically inhibits heat shock protein mRNA translation
    • Hess MA, Duncan RF (1996) Sequence and structure determinants of Drosophila Hsp70 mRNA translation: 5′¢-UTR secondary structure specifically inhibits heat shock protein mRNA translation. Nucleic Acids Res 24:2441-2449
    • (1996) Nucleic Acids Res , vol.24 , pp. 2441-2449
    • Hess, M.A.1    Duncan, R.F.2
  • 23
    • 27744569843 scopus 로고    scopus 로고
    • MTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
    • Holz MK, Ballif BA, Gygi SP, Blenis J (2005) mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. Cell 123:569-580
    • (2005) Cell , vol.123 , pp. 569-580
    • Holz, M.K.1    Ballif, B.A.2    Gygi, S.P.3    Blenis, J.4
  • 24
    • 0022474535 scopus 로고
    • Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22
    • Hultmark D, Klemenz R, Gehring WJ (1986) Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22. Cell 44:429-438
    • (1986) Cell , vol.44 , pp. 429-438
    • Hultmark, D.1    Klemenz, R.2    Gehring, W.J.3
  • 25
    • 0020442218 scopus 로고
    • Ecdysterone induces the transcription of four heat-shock genes in Drosophila S3 cells and imaginal discs
    • Ireland RC, Berger E, Sirotkin K, Yund MA, Osterbur D, Fristrom J (1982) Ecdysterone induces the transcription of four heat-shock genes in Drosophila S3 cells and imaginal discs. Dev Biol 93:498-507
    • (1982) Dev Biol , vol.93 , pp. 498-507
    • Ireland, R.C.1    Berger, E.2    Sirotkin, K.3    Yund, M.A.4    Osterbur, D.5    Fristrom, J.6
  • 26
    • 0025804510 scopus 로고
    • Heat shock impairs the interaction of cap-binding protein complex with 5′¢ mRNA cap
    • Lamphear BJ, Panniers R (1991) Heat shock impairs the interaction of cap-binding protein complex with 5′¢ mRNA cap. J Biol Chem 266:2789-2794
    • (1991) J Biol Chem , vol.266 , pp. 2789-2794
    • Lamphear, B.J.1    Panniers, R.2
  • 27
    • 0028306903 scopus 로고
    • Heat shock-induced repression of proteolysis:poly(A)-binding protein degradation patterns can illusorily suggest its specific loss during heat shock
    • Lefrere V, Duncan RF (1994) Heat shock-induced repression of proteolysis:poly(A)-binding protein degradation patterns can illusorily suggest its specific loss during heat shock. Nucleic Acids Res 22:1640-1642
    • (1994) Nucleic Acids Res , vol.22 , pp. 1640-1642
    • Lefrere, V.1    Duncan, R.F.2
  • 28
    • 0029069981 scopus 로고
    • Rapid turnover of heat shock protein 70 in Drosophila: Stabilization during heat shock, and consequent effects on accumulation
    • Li D, Duncan RF (1995) Rapid turnover of heat shock protein 70 in Drosophila: stabilization during heat shock, and consequent effects on accumulation. Eur J Biochem 231:454-465
    • (1995) Eur J Biochem , vol.231 , pp. 454-465
    • Li, D.1    Duncan, R.F.2
  • 29
    • 0019325433 scopus 로고
    • Varying patterns of protein synthesis in Drosophila during heat shock: Implications for regulation
    • Lindquist S (1980a) Varying patterns of protein synthesis in Drosophila during heat shock: implications for regulation. Dev Biol 77:463-479
    • (1980) Dev Biol , vol.77 , pp. 463-479
    • Lindquist, S.1
  • 30
    • 0019332234 scopus 로고
    • Translational efficiency of heat-induced messages in Drosophila melanogaster cells
    • Lindquist S (1980b) Translational efficiency of heat-induced messages in Drosophila melanogaster cells. J Mol Biol 137:151-158
    • (1980) J Mol Biol , vol.137 , pp. 151-158
    • Lindquist, S.1
  • 31
    • 0022555843 scopus 로고
    • The heat-shock response
    • Lindquist S (1986) The heat -shock response. Ann Rev Biochem 55:1151-1191
    • (1986) Ann Rev Biochem , vol.55 , pp. 1151-1191
    • Lindquist, S.1
  • 32
    • 0025659437 scopus 로고
    • Selective translation and degradation of heat-shock messenger RNAs in Drosophila
    • Lindquist S, Petersen R (1990) Selective translation and degradation of heat-shock messenger RNAs in Drosophila. Enzyme 44:147-166
    • (1990) Enzyme , vol.44 , pp. 147-166
    • Lindquist, S.1    Petersen, R.2
  • 33
    • 0022133046 scopus 로고
    • The preferential translation of Drosophila hsp70 mRNA requires sequences in the untranslated leader
    • McGarry TJ, Lindquist S (1985) The preferential translation of Drosophila hsp70 mRNA requires sequences in the untranslated leader. Cell 42:903-911
    • (1985) Cell , vol.42 , pp. 903-911
    • McGarry, T.J.1    Lindquist, S.2
  • 34
    • 0034976004 scopus 로고    scopus 로고
    • The translational inhibitor 4E-BP is an effector of PI(3) K/Akt signalling and cell growth in Drosophila
    • Miron M, Verdu J, Lachance PE, Birnbaum MJ, Lasko PF, Sonenberg N (2001) The translational inhibitor 4E-BP is an effector of PI(3) K/Akt signalling and cell growth in Drosophila. Nat Cell Biol 3:596-601
    • (2001) Nat Cell Biol , vol.3 , pp. 596-601
    • Miron, M.1    Verdu, J.2    Lachance, P.E.3    Birnbaum, M.J.4    Lasko, P.F.5    Sonenberg, N.6
  • 35
    • 0344629443 scopus 로고    scopus 로고
    • Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster
    • Miron M, Lasko PF, Sonenberg N (2003) Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster. Mol Cell Biol 23:9117-9126
    • (2003) Mol Cell Biol , vol.23 , pp. 9117-9126
    • Miron, M.1    Lasko, P.F.2    Sonenberg, N.3
  • 36
    • 0037031845 scopus 로고    scopus 로고
    • Phosphorylation of initiation factor (eIF) 4E is not required for de novo protein synthesis following recovery from hypertonic stress in human kidney cells
    • Morley SJ, Naegele S (2002) Phosphorylation of initiation factor (eIF) 4E is not required for de novo protein synthesis following recovery from hypertonic stress in human kidney cells. J Biol Chem 277:32855-32859
    • (2002) J Biol Chem , vol.277 , pp. 32855-32859
    • Morley, S.J.1    Naegele, S.2
  • 37
    • 0016711037 scopus 로고
    • High resolution two-dimensional electrophoresis of proteins
    • O'Farrell PH (1975) High resolution two-dimensional electrophoresis of proteins. J Biol Chem 250:4007-4021
    • (1975) J Biol Chem , vol.250 , pp. 4007-4021
    • O'Farrell, P.H.1
  • 38
    • 0022374761 scopus 로고
    • Mechanism of inhibition of polypeptide chain initiation in heat-shocked Ehrlich cells involves reduction of eukaryotic initiation factor 4F activity
    • Panniers R, Stewart EB, Merrick WC, Henshaw EC (1985) Mechanism of inhibition of polypeptide chain initiation in heat-shocked Ehrlich cells involves reduction of eukaryotic initiation factor 4F activity. J Biol Chem 260:9648-9653
    • (1985) J Biol Chem , vol.260 , pp. 9648-9653
    • Panniers, R.1    Stewart, E.B.2    Merrick, W.C.3    Henshaw, E.C.4
  • 39
    • 0027135501 scopus 로고
    • The function of heat -shock proteins in stress tolerance: Degradation and reactivation of damaged proteins
    • Parsell DA, Lindquist S (1993) The function of heat -shock proteins in stress tolerance: degradation and reactivation of damaged proteins. Annu Rev Genet 27:437-496
    • (1993) Annu Rev Genet , vol.27 , pp. 437-496
    • Parsell, D.A.1    Lindquist, S.2
  • 40
    • 0034141942 scopus 로고    scopus 로고
    • Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI
    • Raught B, Gingras AC, Gygi SP, Imataka H, Morino S, Gradi A, Aebersold R, Sonenberg N (2000) Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI. EMBO J 19:434-444
    • (2000) EMBO J , vol.19 , pp. 434-444
    • Raught, B.1    Gingras, A.C.2    Gygi, S.P.3    Imataka, H.4    Morino, S.5    Gradi, A.6    Aebersold, R.7    Sonenberg, N.8
  • 42
    • 0029116649 scopus 로고
    • Cap-independent translation of heat shock messenger RNAs
    • Rhoads RE, Lamphear BJ (1995) Cap-independent translation of heat shock messenger RNAs. Curr Top Microbiol Immunol 203:131-153
    • (1995) Curr Top Microbiol Immunol , vol.203 , pp. 131-153
    • Rhoads, R.E.1    Lamphear, B.J.2
  • 43
    • 34250561475 scopus 로고
    • A new puffing pattern induced by temperature shock and DNP in Drosophila
    • Ritossa FM (1962) A new puffing pattern induced by temperature shock and DNP in Drosophila. Experientia 18:571-573
    • (1962) Experientia , vol.18 , pp. 571-573
    • Ritossa, F.M.1
  • 44
    • 0028979963 scopus 로고
    • 7GpppG cap dependence for efficient translation of Drosophila HSP70 mRNA
    • 7GpppG cap dependence for efficient translation of Drosophila HSP70 mRNA. Eur J Biochem 232:778-788
    • (1995) Eur J Biochem , vol.232 , pp. 778-788
    • Song, H.-J.1    Gallie, D.R.2    Duncan, R.F.3
  • 45
    • 0019124238 scopus 로고
    • Translational control of protein synthesis in response to heat shock in D. melanogaster cells
    • Storti RV, Scott MP, Rich A, Pardue ML (1980) Translational control of protein synthesis in response to heat shock in D. melanogaster cells. Cell 22:825-834
    • (1980) Cell , vol.22 , pp. 825-834
    • Storti, R.V.1    Scott, M.P.2    Rich, A.3    Pardue, M.L.4
  • 46
    • 12644303224 scopus 로고    scopus 로고
    • Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G
    • Tarun SZ Jr., Sachs AB (1996) Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G. EMBO J 15:7168-7177
    • (1996) EMBO J , vol.15 , pp. 7168-7177
    • Tarun Jr., S.Z.1    Sachs, A.B.2
  • 47
    • 0016373748 scopus 로고
    • Protein synthesis in salivary glands of Drosophila melanogaster: Relation to chromosome puffs
    • Tissieres A, Mitchell HK, Tracy WM (1974) Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs. J Mol Biol 84:389-398
    • (1974) J Mol Biol , vol.84 , pp. 389-398
    • Tissieres, A.1    Mitchell, H.K.2    Tracy, W.M.3
  • 48
    • 0034090845 scopus 로고    scopus 로고
    • Translation by ribosome shunting on adenovirus and hsp70 mRNAs facilitated by complementarity to 18S rRNA
    • Yueh A, Schneider RJ (2000) Translation by ribosome shunting on adenovirus and hsp70 mRNAs facilitated by complementarity to 18S rRNA. Genes Dev 14:414-421
    • (2000) Genes Dev , vol.14 , pp. 414-421
    • Yueh, A.1    Schneider, R.J.2
  • 49
    • 0025936233 scopus 로고
    • Inactivation of mRNA cap-binding protein complex in Drosophila melanogaster embryos under heat shock
    • Zapata JM, Maroto FG, Sierra JM (1991) Inactivation of mRNA cap-binding protein complex in Drosophila melanogaster embryos under heat shock. J Biol Chem 266:16007-16014
    • (1991) J Biol Chem , vol.266 , pp. 16007-16014
    • Zapata, J.M.1    Maroto, F.G.2    Sierra, J.M.3
  • 50
    • 0028284411 scopus 로고
    • Purification and characterization of eukaryotic polypeptide chain initiation factor 4F from Drosophila melanogaster embryos
    • Zapata JM, Martinez MA, Sierra JM (1994) Purification and characterization of eukaryotic polypeptide chain initiation factor 4F from Drosophila melanogaster embryos. J Biol Chem 269:18047-18052
    • (1994) J Biol Chem , vol.269 , pp. 18047-18052
    • Zapata, J.M.1    Martinez, M.A.2    Sierra, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.