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Volumn 135, Issue 1, 2009, Pages 128-130

The double-edged sword of statin immunomodulation

Author keywords

Cancer; Infectious diseases; Neurodegenerative disorders; Statins; Tregs

Indexed keywords

ATORVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PENICILLIN G; PRAVASTATIN;

EID: 67349193977     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2008.01.023     Document Type: Article
Times cited : (44)

References (31)
  • 1
    • 35549012363 scopus 로고    scopus 로고
    • Current questions regarding the use of statins in patients with coronary heart disease
    • Rallidis L.S., Lekakis J., and Kremastinos D.T. Current questions regarding the use of statins in patients with coronary heart disease. Int J Cardiol 122 (2007) 188-194
    • (2007) Int J Cardiol , vol.122 , pp. 188-194
    • Rallidis, L.S.1    Lekakis, J.2    Kremastinos, D.T.3
  • 2
    • 2542461241 scopus 로고    scopus 로고
    • Optimal low-density protein is 50 to 70 mg/dl: lower is better and physiologically normal
    • O'Keefe Jr. J.H., Cordain L., Harris W.H., Moe R.M., and Vogel R. Optimal low-density protein is 50 to 70 mg/dl: lower is better and physiologically normal. J Am Coll Cardiol 43 (2004) 2142-2146
    • (2004) J Am Coll Cardiol , vol.43 , pp. 2142-2146
    • O'Keefe Jr., J.H.1    Cordain, L.2    Harris, W.H.3    Moe, R.M.4    Vogel, R.5
  • 3
    • 34447627450 scopus 로고    scopus 로고
    • Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials
    • Alsheikh A.A., Maddukuri P.V., Han H., and Karas R.H. Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials. J Am Coll Cardiol 50 (2007) 409-418
    • (2007) J Am Coll Cardiol , vol.50 , pp. 409-418
    • Alsheikh, A.A.1    Maddukuri, P.V.2    Han, H.3    Karas, R.H.4
  • 4
    • 40949143105 scopus 로고    scopus 로고
    • The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells
    • Mausner-Fainberg K., Luboshits G., Mor A., et al. The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells. Atherosclerosis 197 (2008) 829-839
    • (2008) Atherosclerosis , vol.197 , pp. 829-839
    • Mausner-Fainberg, K.1    Luboshits, G.2    Mor, A.3
  • 5
    • 25444463325 scopus 로고    scopus 로고
    • Regulatory T cell responses: potential role in the control of atherosclerosis
    • Mallat Z., Ait-Oufella H., and Tedgui A. Regulatory T cell responses: potential role in the control of atherosclerosis. Curr Opin Lipidol 16 (2005) 518-524
    • (2005) Curr Opin Lipidol , vol.16 , pp. 518-524
    • Mallat, Z.1    Ait-Oufella, H.2    Tedgui, A.3
  • 6
    • 34447256838 scopus 로고    scopus 로고
    • Regulatory T lymphocytes: pivotal components of the host antitumor response
    • Yakirevich E., and Resnick M.B. Regulatory T lymphocytes: pivotal components of the host antitumor response. J Clin Oncol 25 (2007) 2506-2508
    • (2007) J Clin Oncol , vol.25 , pp. 2506-2508
    • Yakirevich, E.1    Resnick, M.B.2
  • 7
    • 34248194231 scopus 로고    scopus 로고
    • Tregs and rethinking cancer immunotherapy
    • Curiel T.J. Tregs and rethinking cancer immunotherapy. J Clin Invest 117 (2007) 1167-1174
    • (2007) J Clin Invest , vol.117 , pp. 1167-1174
    • Curiel, T.J.1
  • 8
    • 34247261531 scopus 로고    scopus 로고
    • Quantification or regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
    • Bates G.J., Fox S.B., Han C., et al. Quantification or regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J Clin Oncol 24 (2006) 5373-5380
    • (2006) J Clin Oncol , vol.24 , pp. 5373-5380
    • Bates, G.J.1    Fox, S.B.2    Han, C.3
  • 9
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel T.J., Coukos G., Zou L., et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 10 (2004) 942-949
    • (2004) Nat Med , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 10
    • 33847384529 scopus 로고    scopus 로고
    • FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis
    • Kobayashi N., Nobuyoshi H., Yamagami W., et al. FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis. Clin Cancer Res 13 (2007) 902-911
    • (2007) Clin Cancer Res , vol.13 , pp. 902-911
    • Kobayashi, N.1    Nobuyoshi, H.2    Yamagami, W.3
  • 11
    • 0342981862 scopus 로고    scopus 로고
    • The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
    • The Cholesterol and Recurrent Events Trial Investigators
    • The Cholesterol and Recurrent Events Trial Investigators. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med 335 (1996) 1001-1009
    • (1996) N Engl J Med , vol.335 , pp. 1001-1009
  • 12
    • 35248901000 scopus 로고    scopus 로고
    • Long-term follow-up of the West of Scotland Coronary Prevention Study
    • West of Scotland Coronary Prevention-Study Group
    • West of Scotland Coronary Prevention-Study Group. Long-term follow-up of the West of Scotland Coronary Prevention Study. N Engl J Med 357 (2007) 1477-1486
    • (2007) N Engl J Med , vol.357 , pp. 1477-1486
  • 13
    • 33750807427 scopus 로고    scopus 로고
    • CD4+CD25 high T cells are enriched in the tumor and peripheral blood of prostate cancer patients
    • Miller A.M., Lundberg K., Ozenci V., et al. CD4+CD25 high T cells are enriched in the tumor and peripheral blood of prostate cancer patients. J Immunol 177 (2006) 7398-7405
    • (2006) J Immunol , vol.177 , pp. 7398-7405
    • Miller, A.M.1    Lundberg, K.2    Ozenci, V.3
  • 15
    • 0037164314 scopus 로고    scopus 로고
    • Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial
    • The PROSPER Study Group
    • The PROSPER Study Group. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet 360 (2002) 1623-1630
    • (2002) Lancet , vol.360 , pp. 1623-1630
  • 16
    • 0035873251 scopus 로고    scopus 로고
    • Benefits of pravastatin on cardiovascular events and mortality in older patients with coronary heart disease are equal to or exceed those seen in younger patients: results from the LIPID trial
    • The LIPID Investigators
    • The LIPID Investigators. Benefits of pravastatin on cardiovascular events and mortality in older patients with coronary heart disease are equal to or exceed those seen in younger patients: results from the LIPID trial. Ann Intern Med 134 (2001) 931-940
    • (2001) Ann Intern Med , vol.134 , pp. 931-940
  • 17
    • 34447274822 scopus 로고    scopus 로고
    • Outcomes of using high- or low-dose atorvastatin in patients 65 years or older with stable coronary heart disease
    • The Treating to New Targets Study Steering Committee and Investigators
    • The Treating to New Targets Study Steering Committee and Investigators. Outcomes of using high- or low-dose atorvastatin in patients 65 years or older with stable coronary heart disease. Ann Intern Med 147 (2007) 1-9
    • (2007) Ann Intern Med , vol.147 , pp. 1-9
  • 18
    • 33845700951 scopus 로고    scopus 로고
    • Use of statins and outcome of BCG treatment for bladder cancer
    • Hoffmann P., Roumeguere T., and van Velthoven R. Use of statins and outcome of BCG treatment for bladder cancer. N Engl J Med 355 (2006) 2705-2707
    • (2006) N Engl J Med , vol.355 , pp. 2705-2707
    • Hoffmann, P.1    Roumeguere, T.2    van Velthoven, R.3
  • 19
    • 34249902026 scopus 로고    scopus 로고
    • Statins, neuromuscular degenerative disease and an amyotrophic lateral sclerosis-like syndrome: an analysis of individual case safety reports from Vigibase
    • Edwards I.R., Star K., and Kiuru A. Statins, neuromuscular degenerative disease and an amyotrophic lateral sclerosis-like syndrome: an analysis of individual case safety reports from Vigibase. Drug Saf 30 (2007) 515-525
    • (2007) Drug Saf , vol.30 , pp. 515-525
    • Edwards, I.R.1    Star, K.2    Kiuru, A.3
  • 21
    • 0036708987 scopus 로고    scopus 로고
    • Myelin specific Th1 cells are necessary for post-traumatic protective autoimmunity
    • Kipnis J., Yoles E., Mizrahi T., Ben-Nur A., and Schwartz M. Myelin specific Th1 cells are necessary for post-traumatic protective autoimmunity. J Neuroimmuno 130 (2002) 78-85
    • (2002) J Neuroimmuno , vol.130 , pp. 78-85
    • Kipnis, J.1    Yoles, E.2    Mizrahi, T.3    Ben-Nur, A.4    Schwartz, M.5
  • 22
    • 0037180556 scopus 로고    scopus 로고
    • Neuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system
    • Kipnis J., Mizrahi T., Hauben E., et al. Neuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system. PNAS 99 (2002) 15620-15625
    • (2002) PNAS , vol.99 , pp. 15620-15625
    • Kipnis, J.1    Mizrahi, T.2    Hauben, E.3
  • 23
    • 16844369607 scopus 로고    scopus 로고
    • Natural regulatory T cells in infectious disease
    • Belkaid Y., and Rouse B. Natural regulatory T cells in infectious disease. Nat Immunol 6 (2005) 353-360
    • (2005) Nat Immunol , vol.6 , pp. 353-360
    • Belkaid, Y.1    Rouse, B.2
  • 24
    • 4043102582 scopus 로고    scopus 로고
    • Regulatory cells and infectious agents: detentes cordiale and contraire
    • Rouse B.T., and Suvas S. Regulatory cells and infectious agents: detentes cordiale and contraire. J Immunol 173 (2004) 2211-2215
    • (2004) J Immunol , vol.173 , pp. 2211-2215
    • Rouse, B.T.1    Suvas, S.2
  • 25
    • 10744227590 scopus 로고    scopus 로고
    • Human CD4+CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens
    • Aandahl E.M., Michaelsson J., Moretto W.J., Hecht F.M., and Nixon D.F. Human CD4+CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens. J Virol 78 (2004) 2454-2459
    • (2004) J Virol , vol.78 , pp. 2454-2459
    • Aandahl, E.M.1    Michaelsson, J.2    Moretto, W.J.3    Hecht, F.M.4    Nixon, D.F.5
  • 26
    • 33847667461 scopus 로고    scopus 로고
    • Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals
    • Kitner A., McNally J., Riggin L., et al. Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals. PNAS 104 (2007) 3390-3395
    • (2007) PNAS , vol.104 , pp. 3390-3395
    • Kitner, A.1    McNally, J.2    Riggin, L.3
  • 27
    • 16244385911 scopus 로고    scopus 로고
    • Regulatory T-cells contribute to the impaired immune response in patients with chronic hepatitis B viral infection
    • Stoop J.N., van der Molen R.G., Baan C.C., et al. Regulatory T-cells contribute to the impaired immune response in patients with chronic hepatitis B viral infection. Hepatology 41 (2005) 771-778
    • (2005) Hepatology , vol.41 , pp. 771-778
    • Stoop, J.N.1    van der Molen, R.G.2    Baan, C.C.3
  • 28
    • 7044247947 scopus 로고    scopus 로고
    • An immunomodulatory role for CD4+CD25+ regulatory T lymphocytes in hepatitis C virus infection
    • Cabrera R., Tu Z., Xu Y., et al. An immunomodulatory role for CD4+CD25+ regulatory T lymphocytes in hepatitis C virus infection. Hepatology 40 (2004) 1062-1071
    • (2004) Hepatology , vol.40 , pp. 1062-1071
    • Cabrera, R.1    Tu, Z.2    Xu, Y.3
  • 29
    • 35848954757 scopus 로고    scopus 로고
    • A population-based study of the incidence and complication rates of herpes zoster before zoster vaccine introduction
    • Yawn B.P., Saddier P., Wollan P.C., et al. A population-based study of the incidence and complication rates of herpes zoster before zoster vaccine introduction. Mayo Clin Proc 82 (2007) 1341-1349
    • (2007) Mayo Clin Proc , vol.82 , pp. 1341-1349
    • Yawn, B.P.1    Saddier, P.2    Wollan, P.C.3
  • 30
    • 67349169052 scopus 로고    scopus 로고
    • Accessed November 18, 2007
    • Lipitor prescribing information, Table 8, http://www.pfizer.com/files/products/uspi_lipitor.pdf (Accessed November 18, 2007).
    • Lipitor prescribing information, Table 8
  • 31
    • 0029837212 scopus 로고    scopus 로고
    • The underused miracle drugs: the statin drugs are to atherosclerosis what penicillin was to infectious disease
    • Roberts W.C. The underused miracle drugs: the statin drugs are to atherosclerosis what penicillin was to infectious disease. Am J Cardiol 78 (1996) 377-378
    • (1996) Am J Cardiol , vol.78 , pp. 377-378
    • Roberts, W.C.1


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