The role of corneocytes in skin transport revised-a combined computational and experimental approach

Pharmaceutical Research

Volumn 26, Issue 6, 2009, Pages 1379-1397

  Hansen, Steffi ^a   Naegel, Arne ^b   Heisig, Michael ^b   Wittum, Gabriel ^b   Neumann, Dirk ^a   Kostka, Karl Heinz ^c   Meiers, Peter ^a   Lehr, Claus Michael ^a   Schaefer, Ulrich F ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c Caritas Hospital   (Germany)

Author keywords

Compartmental model; Dual sorption theory; Langmuir isotherm; Partition coefficient; Skin

Indexed keywords

CAFFEINE; FLUFENAMIC ACID; LIPID; TESTOSTERONE; WATER;

ARTICLE; BINDING AFFINITY; COMPARTMENT MODEL; DISSOLUTION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROPHILICITY; LANGMUIR BLODGETT FILM; LIPOPHILICITY; MATHEMATICAL ANALYSIS; PARTITION COEFFICIENT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; SKIN CELL; SKIN PERMEABILITY; STRATUM CORNEUM;

BIOLOGICAL TRANSPORT; CAFFEINE; EPIDERMIS; FEMALE; FLUFENAMIC ACID; HUMANS; KERATINS; LIPIDS; MODELS, BIOLOGICAL; PROTEIN BINDING; SKIN ABSORPTION; SOLUBILITY; TESTOSTERONE; WATER;

EID: 67349168478     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9849-7     Document Type: Article

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